DRSC/TRiP Functional Genomics Resources

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Protein Alignment Stip1 and zgc:123010

DIOPT Version :9

Sequence 1:NP_477354.1 Gene:Stip1 / 33202 FlyBaseID:FBgn0024352 Length:490 Species:Drosophila melanogaster
Sequence 2:XP_005169572.1 Gene:zgc:123010 / 641500 ZFINID:ZDB-GENE-051120-15 Length:501 Species:Danio rerio


Alignment Length:303 Identity:74/303 - (24%)
Similarity:135/303 - (44%) Gaps:28/303 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   163 EDMTEEQKNKYFARKEKELGNAAYKKKDFETALKHYHAAIEHDPTDITFYNNIAAVHFERKEYEE 227
            |.::||:|.:..|.:.|.......::|..|...|......|.:..:.....:.|....|..|.||
Zfish    50 EGLSEEEKARRKAERRKAKRKRQRQRKKLERVKKDESTEQEEEEEEEEEEEDDAGPDSELDESEE 114

  Fly   228 CIKQCEKGIEVGRESRADFKLIAKSFA----RIGNTYRKLENYKQAK---------VYYEKAMSE 279
              .:.|: :.|.:.......|:.||.:    ..||...:.:..:..:         .:...|:| 
Zfish   115 --SELEE-VVVSKVEEKPVALLNKSPSGPPLASGNKSNRQQGARSGEEDPGWDVNSAFVANAVS- 175

  Fly   280 HRTPEIKTSLSEVEAKIKEEERMAYINPEKAEEEK-----EQGNLFFKKGDYSTAVKHYTEAIKR 339
            |..|:.|:.....|.|..|......|...:|:.::     |:|..|.::|.|:.||..:|||||.
Zfish   176 HIRPKAKSKGKSKENKENESRPAEVIGFSEAKTKRSASLVEKGIRFVQEGQYTQAVSLFTEAIKC 240

  Fly   340 NPDDPKLYSNRAACYTKLAAFDLGLKDCDTCIKLDEKFIKGYIRKGKILQGMQQQSKAQAAYQKA 404
            :|.|.:.:.||:.||..|..:.|.|.|.:..|::...:.|||.|:|..|.|:::.|:|:.|.::.
Zfish   241 DPKDYRFFGNRSYCYCCLEQYALALADAEKSIQMAPDWPKGYYRRGSALMGLKRYSEAEKAMEQV 305

  Fly   405 LELDPNNAEAIEGYRQCSMNFQRNPQEVLKNAMSDPEIQQILK 447
            |:||.:..||:.....|.:      |::.:....:.:..|:|:
Zfish   306 LKLDGDCEEAVNDLLYCKV------QQLTELGYDEEQSIQLLE 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Stip1NP_477354.1 TPR_11 6..69 CDD:290150
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR_11 40..103 CDD:290150
TPR repeat 72..100 CDD:276809
TPR_11 175..237 CDD:290150 12/61 (20%)
TPR repeat 175..203 CDD:276809 5/27 (19%)
TPR_1 181..208 CDD:278916 4/26 (15%)
TPR_12 205..278 CDD:290160 13/85 (15%)
TPR repeat 208..238 CDD:276809 6/29 (21%)
TPR repeat 250..278 CDD:276809 5/40 (13%)
TPR_1 250..>276 CDD:278916 4/38 (11%)
TPR_11 309..375 CDD:290150 24/70 (34%)
TPR repeat 310..338 CDD:276809 11/32 (34%)
TPR_1 <317..343 CDD:278916 12/25 (48%)
TPR repeat 343..373 CDD:276809 10/29 (34%)
TPR_1 378..411 CDD:278916 13/32 (41%)
TPR repeat 378..406 CDD:276809 10/27 (37%)
STI1 439..478 CDD:128966 2/9 (22%)
zgc:123010XP_005169572.1 TPR_11 214..276 CDD:290150 23/61 (38%)
TPR repeat 214..239 CDD:276809 10/24 (42%)
TPR repeat 244..274 CDD:276809 10/29 (34%)
TPR_11 250..309 CDD:290150 20/58 (34%)
TPR_2 279..309 CDD:285020 11/29 (38%)
TPR repeat 279..307 CDD:276809 10/27 (37%)
TPR_11 282..343 CDD:290150 17/67 (25%)
TPR repeat 313..343 CDD:276809 6/36 (17%)
RRM <364..>438 CDD:223796
RRM 370..436 CDD:214636
zf-CCCH 471..492 CDD:279036
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001589
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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