DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stip1 and sugt1

DIOPT Version :9

Sequence 1:	NP_477354.1	Gene:	Stip1 / 33202	FlyBaseID:	FBgn0024352	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001016156.1	Gene:	sugt1 / 548910	XenbaseID:	XB-GENE-919559	Length:	330	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	68/344 - (19%)
Similarity:	121/344 - (35%)	Gaps:	76/344 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TEAIALDDQNHVLYSNRSAAFAKAGKFQEALEDAEKTIQLNPTWPKGYSRKGAAAAGLNDFMKAF 92
            |:||.........|..|:.|......:.:|:.||:::::|.|.....:.|||.|...|.::..|.
Frog    29 TKAIEEKSDCAEYYCQRAYAHILLQNYNDAVLDAKRSLELQPNNASAFLRKGEAEFHLQNYSSAE 93

  Fly    93 EAYNEGLKYD------PTNAILLQGRMETTASALSFMQSQGDIPMDVDPQQARSRRAPSPPPAKP 151
            |::.:|...|      ||...|.:.::..:....|....|..:....|..|..|...
Frog    94 ESFKKGQILDASTPTFPTWIKLCEEKLNVSTEGQSSNNQQTSVKYRHDWYQTESHII-------- 150

  Fly   152 AEPPKPAEPRVEDMTEE-QKNKY---FARKEKELGNAAYKKKDFETALKHYHAAIEHDPTDITFY 212
                      :..|.:. |||..   |:.:|..:..:....:::...|...||.:   |....|
Frog   151 ----------ITVMIKNVQKNNVHIRFSERELTVNMSLPSGENYSLNLHLLHAIV---PDQSIF- 201

  Fly   213 NNIAAVHFERKEYEECIKQCEKGIEVGRESRADFKLIAKSFARIGNTYRKLENYKQAKVYYEKAM 277
             .:.:...|.|     :|:.|.......|.:||.::  |.|     |...:..|..
Frog   202 -KVLSTKVEIK-----LKKTEAMRWETLEGKADSQV--KHF-----TQESMHKYPS--------- 244

  Fly   278 SEHRTPEIKTSLSEVEAKIKEEERMAYINPEKA-------------EEEKEQGNLFFKKGDYSTA 329
            |.|.|    .:..::..:|||||:...:..:.|             :|.|...|..|.:...:..
Frog   245 SSHYT----KNWDKLVGQIKEEEKNEKLEGDAALNQLFQQIYSDGNDEVKRAMNKSFMESGGTVL 305

  Fly   330 VKHYTEAIKRN-----PDD 343
            ..::|:..|:.     |||
Frog   306 STNWTDVGKKKVDVNPPDD 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stip1	NP_477354.1	TPR_11	6..69	CDD:290150	10/40 (25%)
		TPR repeat	7..32	CDD:276809	2/3 (67%)
		TPR repeat	37..67	CDD:276809	6/29 (21%)
		TPR_11	40..103	CDD:290150	17/68 (25%)
		TPR repeat	72..100	CDD:276809	8/27 (30%)
		TPR_11	175..237	CDD:290150	10/61 (16%)
		TPR repeat	175..203	CDD:276809	4/27 (15%)
		TPR_1	181..208	CDD:278916	4/26 (15%)
		TPR_12	205..278	CDD:290160	13/72 (18%)
		TPR repeat	208..238	CDD:276809	5/29 (17%)
		TPR repeat	250..278	CDD:276809	4/27 (15%)
		TPR_1	250..>276	CDD:278916	4/25 (16%)
		TPR_11	309..375	CDD:290150	10/53 (19%)
		TPR repeat	310..338	CDD:276809	6/40 (15%)
		TPR_1	<317..343	CDD:278916	5/30 (17%)
		TPR repeat	343..373	CDD:276809	1/1 (100%)
		TPR_1	378..411	CDD:278916
		TPR repeat	378..406	CDD:276809
		STI1	439..478	CDD:128966
sugt1	NP_001016156.1	PLN03088	15..330	CDD:330826	68/344 (20%)
		TPR repeat	38..68	CDD:276809	6/29 (21%)
		TPR repeat	73..98	CDD:276809	7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910