DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stip1 and CG6980

DIOPT Version :9

Sequence 1:	NP_477354.1	Gene:	Stip1 / 33202	FlyBaseID:	FBgn0024352	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_651289.1	Gene:	CG6980 / 42955	FlyBaseID:	FBgn0039228	Length:	250	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	48/156 - (30%)
Similarity:	74/156 - (47%)	Gaps:	12/156 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 ENYKQAKVYYEKAMSEHRTPEIKTSLSEVEAKIKEEERMAYINPEKAEEEKEQGNLFFKKGDYST 328
            :|.||.|...:|:..|...   |.:....||:.|.|        .:||.::.|||..|:...|..
  Fly    93 DNEKQVKDMNQKSFMEQVE---KDANDRAEARAKAE--------YEAELQRSQGNEAFRSQKYEK 146

  Fly   329 AVKHYTEAIKRNPDDPKLYSNRAACYTKLAAFDLGLKDCDTCI-KLDEKFIKGYIRKGKILQGMQ 392
            |:.||.:||.:..|....|.|||.||.||..:...||||...: ||.|..::.::.:....:|::
  Fly   147 AILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEKLQESNLRAWLYQAHAYKGLK 211

  Fly   393 QQSKAQAAYQKALELDPNNAEAIEGY 418
            |..|.:.:..||.|.:|.....|:.|
  Fly   212 QDDKFEESVVKAREHNPKQLAYIDKY 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stip1	NP_477354.1	TPR_11	6..69	CDD:290150
		TPR repeat	7..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR_11	40..103	CDD:290150
		TPR repeat	72..100	CDD:276809
		TPR_11	175..237	CDD:290150
		TPR repeat	175..203	CDD:276809
		TPR_1	181..208	CDD:278916
		TPR_12	205..278	CDD:290160	5/13 (38%)
		TPR repeat	208..238	CDD:276809
		TPR repeat	250..278	CDD:276809	5/13 (38%)
		TPR_1	250..>276	CDD:278916	4/11 (36%)
		TPR_11	309..375	CDD:290150	27/66 (41%)
		TPR repeat	310..338	CDD:276809	11/27 (41%)
		TPR_1	<317..343	CDD:278916	9/25 (36%)
		TPR repeat	343..373	CDD:276809	12/30 (40%)
		TPR_1	378..411	CDD:278916	7/32 (22%)
		TPR repeat	378..406	CDD:276809	5/27 (19%)
		STI1	439..478	CDD:128966
CG6980	NP_651289.1	TPR_11	127..190	CDD:290150	25/62 (40%)
		TPR repeat	128..156	CDD:276809	11/27 (41%)
		TPR repeat	161..192	CDD:276809	12/30 (40%)
		TPR_1	162..190	CDD:278916	12/27 (44%)
		TPR repeat	197..225	CDD:276809	5/27 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0548
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810