DRSC/TRiP Functional Genomics Resources

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Protein Alignment Stip1 and HIP

DIOPT Version :9

Sequence 1:NP_477354.1 Gene:Stip1 / 33202 FlyBaseID:FBgn0024352 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_570074.3 Gene:HIP / 318211 FlyBaseID:FBgn0260484 Length:377 Species:Drosophila melanogaster


Alignment Length:262 Identity:64/262 - (24%)
Similarity:106/262 - (40%) Gaps:61/262 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDKVNELKEKGNQALSAEKFDEAVAAYTEAIALDDQNHVLYSNRSAAFAKAGKFQEALEDAEKTI 65
            :::.:||:.:...|...:|||||:|.||:||.|...|.:.::.|..||.|..|....:.|.:..:
  Fly   123 VEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVAL 187

  Fly    66 QLNPTWPKGYSRKGAAAAGLNDFMKAFEAYNEGLKYD---PTNAILLQGRMETTASALSFMQSQG 127
            :||.....||..:|.|...|.||..|.....:..|.|   .|:..|    .|.|.:|        
  Fly   188 ELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWL----KEVTPNA-------- 240

  Fly   128 DIPMDVDPQQARSRRAPSPPPAKPAEPPKPAEPRVEDMTEEQKNKYFARKEKELGNAAY------ 186
               ..::..:.:..|             :.||.:::   |.|:::..||||:|..||:.      
  Fly   241 ---KKIEQHRLKQER-------------RQAERKIK---ERQRDQRRARKEQEKHNASSGGSSGE 286

  Fly   187 ---------KKKDFETALK--HYHAAIE---HDPTDITFYNNIAAVHFERKEYEECIKQCEKGIE 237
                     ...|...|:.  ...|||:   .:|.:||.|.:...::       ..||:...|.:
  Fly   287 FSGGNPGNGNMSDILGAMSDPEVSAAIQDILSNPGNITKYASNPKIY-------NLIKKIVPGGD 344

  Fly   238 VG 239
            ||
  Fly   345 VG 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Stip1NP_477354.1 TPR_11 6..69 CDD:290150 22/62 (35%)
TPR repeat 7..32 CDD:276809 11/24 (46%)
TPR repeat 37..67 CDD:276809 7/29 (24%)
TPR_11 40..103 CDD:290150 18/65 (28%)
TPR repeat 72..100 CDD:276809 8/27 (30%)
TPR_11 175..237 CDD:290150 19/81 (23%)
TPR repeat 175..203 CDD:276809 11/44 (25%)
TPR_1 181..208 CDD:278916 8/46 (17%)
TPR_12 205..278 CDD:290160 9/35 (26%)
TPR repeat 208..238 CDD:276809 6/29 (21%)
TPR repeat 250..278 CDD:276809
TPR_1 250..>276 CDD:278916
TPR_11 309..375 CDD:290150
TPR repeat 310..338 CDD:276809
TPR_1 <317..343 CDD:278916
TPR repeat 343..373 CDD:276809
TPR_1 378..411 CDD:278916
TPR repeat 378..406 CDD:276809
STI1 439..478 CDD:128966
HIPNP_570074.3 Hip_N 10..47 CDD:271228
TPR_11 125..190 CDD:290150 21/64 (33%)
TPR_2 126..159 CDD:285020 14/32 (44%)
TPR repeat 126..154 CDD:276809 12/27 (44%)
TPR repeat 159..189 CDD:276809 7/29 (24%)
TPR repeat 194..222 CDD:276809 8/27 (30%)
STI1 299..336 CDD:128966 9/43 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45462457
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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