DRSC/TRiP Functional Genomics Resources

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Protein Alignment Stip1 and sti-1

DIOPT Version :9

Sequence 1:NP_477354.1 Gene:Stip1 / 33202 FlyBaseID:FBgn0024352 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_001367444.1 Gene:sti-1 / 178587 WormBaseID:WBGene00019983 Length:320 Species:Caenorhabditis elegans


Alignment Length:312 Identity:176/312 - (56%)
Similarity:239/312 - (76%) Gaps:0/312 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 EKELGNAAYKKKDFETALKHYHAAIEHDPTDITFYNNIAAVHFERKEYEECIKQCEKGIEVGRES 242
            ||:|||||||:||||.|..||..|||.||::||||||.|||:||.|::.||::.|||.:|||||:
 Worm     8 EKDLGNAAYKQKDFEKAHVHYDKAIELDPSNITFYNNKAAVYFEEKKFAECVQFCEKAVEVGRET 72

  Fly   243 RADFKLIAKSFARIGNTYRKLENYKQAKVYYEKAMSEHRTPEIKTSLSEVEAKIKEEERMAYINP 307
            |||:|||||:.:|.||.::|..:...|..::.:::||.|.||:...:.|:|.::|..||:|||||
 Worm    73 RADYKLIAKAMSRAGNAFQKQNDLSLAVQWFHRSLSEFRDPELVKKVKELEKQLKAAERLAYINP 137

  Fly   308 EKAEEEKEQGNLFFKKGDYSTAVKHYTEAIKRNPDDPKLYSNRAACYTKLAAFDLGLKDCDTCIK 372
            |.|:|||.:||.:||||||.||::||.||:||:|::..||||||||.|||..|...|.||||||:
 Worm   138 ELAQEEKNKGNEYFKKGDYPTAMRHYNEAVKRDPENAILYSNRAACLTKLMEFQRALDDCDTCIR 202

  Fly   373 LDEKFIKGYIRKGKILQGMQQQSKAQAAYQKALELDPNNAEAIEGYRQCSMNFQRNPQEVLKNAM 437
            ||.|||||||||...|..|::.||||.||:.||::||:|.||.||.|.|..:...:|::..:.::
 Worm   203 LDSKFIKGYIRKAACLVAMREWSKAQRAYEDALQVDPSNEEAREGVRNCLRSNDEDPEKAKERSL 267

  Fly   438 SDPEIQQILKDPAMRMILEQMQSDPNAVKEHLQNPAIADKIMKLLESGIIQI 489
            :|||:|:||:||.||||||||.:||.||:|||:||.|..|:|||.::|:||:
 Worm   268 ADPEVQEILRDPGMRMILEQMSNDPGAVREHLKNPEIFQKLMKLRDAGVIQM 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Stip1NP_477354.1 TPR_11 6..69 CDD:290150
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR_11 40..103 CDD:290150
TPR repeat 72..100 CDD:276809
TPR_11 175..237 CDD:290150 38/58 (66%)
TPR repeat 175..203 CDD:276809 17/24 (71%)
TPR_1 181..208 CDD:278916 19/26 (73%)
TPR_12 205..278 CDD:290160 37/72 (51%)
TPR repeat 208..238 CDD:276809 17/29 (59%)
TPR repeat 250..278 CDD:276809 7/27 (26%)
TPR_1 250..>276 CDD:278916 7/25 (28%)
TPR_11 309..375 CDD:290150 41/65 (63%)
TPR repeat 310..338 CDD:276809 18/27 (67%)
TPR_1 <317..343 CDD:278916 17/25 (68%)
TPR repeat 343..373 CDD:276809 19/29 (66%)
TPR_1 378..411 CDD:278916 19/32 (59%)
TPR repeat 378..406 CDD:276809 16/27 (59%)
STI1 439..478 CDD:128966 26/38 (68%)
sti-1NP_001367444.1 3a0801s09 <5..>241 CDD:273380 135/232 (58%)
TPR repeat 5..33 CDD:276809 17/24 (71%)
TPR repeat 38..68 CDD:276809 17/29 (59%)
TPR repeat 80..108 CDD:276809 7/27 (26%)
TPR repeat 140..168 CDD:276809 18/27 (67%)
TPR repeat 173..203 CDD:276809 19/29 (66%)
TPR repeat 208..236 CDD:276809 16/27 (59%)
STI1 259..311 CDD:407696 29/51 (57%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160159896
Domainoid 1 1.000 71 1.000 Domainoid score I6204
eggNOG 1 0.900 - - E2759_KOG0548
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H4965
Inparanoid 1 1.050 376 1.000 Inparanoid score I1211
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53129
OrthoDB 1 1.010 - - D387926at33208
OrthoFinder 1 1.000 - - FOG0001589
OrthoInspector 1 1.000 - - oto17632
orthoMCL 1 0.900 - - OOG6_102012
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1407
SonicParanoid 1 1.000 - - X2280
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1413.740

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