DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2af38 and ATU2AF35A

DIOPT Version :9

Sequence 1:	NP_001259814.1	Gene:	U2af38 / 33201	FlyBaseID:	FBgn0017457	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_174086.1	Gene:	ATU2AF35A / 839657	AraportID:	AT1G27650	Length:	296	Species:	Arabidopsis thaliana

Alignment Length:	286	Identity:	140/286 - (48%)
Similarity:	178/286 - (62%)	Gaps:	38/286 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQ--NSAKSAD 63
            |||:||||||||||:|||.||||||||||||||||:||:||.|.|:||.|:|..|.  .....|.
plant     1 MAEHLASIFGTEKDRVNCPFYFKIGACRHGDRCSRLHNRPTISPTLLLSNMYQRPDMITPGVDAQ 65

  Fly    64 GSHLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKA 128
            |..|    ...::|||:::||||:|.|. .|:||||.:|:||||.||::||||::|:.|..|..|
plant    66 GQPL----DPRKIQEHFEDFFEDLFEEL-GKFGEIESLNICDNLADHMIGNVYVQFKEEDQAAAA 125

  Fly   129 ANDLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRRR 193
            ...|..|::.|||:.::.|||||||||.|||||...|.|.|:|||||:|.:||||||.|:.|.||
plant   126 LQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRR 190

  Fly   194 ARSRSRSPGRRRGSRSRSRS-----PGRRGGGRGDGVGGGNYLNNERD--------NMRGNDRGN 245
            :        .||||||||||     ..:|...|.| .....:.:.:||        ..|.::| :
plant   191 S--------YRRGSRSRSRSRSISPRNKRDNDRRD-PSHREFSHRDRDREFYRHGSGKRSSER-S 245

  Fly   246 DRDRRKGGGG--------GGGGGGGR 263
            :|..|.|..|        ||..||||
plant   246 ERQERDGSRGRRQASPKRGGSPGGGR 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	22/25 (88%)
		RRM_U2AF35	43..148	CDD:240982	44/106 (42%)
		zf-CCCH	151..177	CDD:279036	18/25 (72%)
ATU2AF35A	NP_174086.1	zf-CCCH	13..39	CDD:395517	22/25 (88%)
		RRM_U2AF35B	44..145	CDD:409955	43/105 (41%)
		ZnF_C3H1	148..174	CDD:214632	18/25 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I3566
eggNOG	1	0.900	-	-		E1_KOG2202
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I975
OMA	1	1.010	-	-		QHG56320
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	1	1.000	-	-		FOG0002537
OrthoInspector	1	1.000	-	-		otm3367
orthoMCL	1	0.900	-	-		OOG6_101418
Panther	1	1.100	-	-	O	PTHR12620
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840