Protein Alignment U2af38 and U2AF1

DIOPT Version :9

• Sequence 1: NP_001259814.1
• Gene: U2af38 / 33201
• FlyBaseID: FBgn0017457
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001020374.1
• Gene: U2AF1 / 7307
• HGNCID: 12453
• Length: 240
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 190/254 - (74%)
• Similarity: 206/254 - (81%)
• Gaps: 17/254 - (6%)

  Fly     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGS 65
            |||||||||||||||||||||||||||||||||||:|||||||||:|:||:|.||||||::||||
Human     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQTADGS 65

  Fly    66 HLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAAN 130
            |..  |||.|||||||.|||:||.|.|:||||:||||||||||||||||||:|||.|.|||||..
Human    66 HCA--VSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVI 128

  Fly   131 DLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRRRA- 194
            |||||||.|:|:::|||||||||||||||||||||||.|||||||||||||||||.||.|||:.
Human   129 DLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKH 193

  Fly   195 RSRSRSPGRRRGSRSRSRSPGRRGGGRGDGVGGGNYLNNERDNMRGNDRGNDRDRRKGG 253
            ||||||    |..|||||..||.|||.|.|.|||          |..||...|||.:.|
Human   194 RSRSRS----RERRSRSRDRGRGGGGGGGGGGGG----------RERDRRRSRDRERSG 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	24/25 (96%)
		RRM_U2AF35	43..148	CDD:240982	77/104 (74%)
		zf-CCCH	151..177	CDD:279036	24/25 (96%)
U2AF1	NP_001020374.1	zf-CCCH	13..39	CDD:395517	24/25 (96%)
		RRM_U2AF35	43..146	CDD:409954	77/104 (74%)
		zf-CCCH	149..175	CDD:395517	24/25 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147842
Domainoid	1	1.000	94	1.000	Domainoid score	I7476
eggNOG	1	0.900	-	-		E1_KOG2202
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	377	1.000	Inparanoid score	I2090
Isobase	1	0.950	-	0	Normalized mean entropy	S1692
OMA	1	1.010	-	-		QHG56320
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	1	1.000	-	-		FOG0002537
OrthoInspector	1	1.000	-	-		otm41715
orthoMCL	1	0.900	-	-		OOG6_101418
Panther	1	1.100	-	-	LDO	PTHR12620
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4380
SonicParanoid	1	1.000	-	-		X1660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.750