DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment U2af38 and U2af1

DIOPT Version :9

Sequence 1:	NP_001259814.1	Gene:	U2af38 / 33201	FlyBaseID:	FBgn0017457	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001037756.1	Gene:	U2af1 / 687575	RGDID:	1584190	Length:	239	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	186/253 - (73%)
Similarity:	202/253 - (79%)	Gaps:	16/253 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGS 65
            |||||||||||||||||||||||||||||||||||:|||||||||:.|.|:|.|||||::||||
  Rat     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADG- 64

  Fly    66 HLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAAN 130
             |...|||.|||||||.|||:||.|.|:||||:||||||||||||||||||:|||.|.|||||..
  Rat    65 -LRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVI 128

  Fly   131 DLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRRRAR 195
            |||||||.|:|:::|||||||||||||||||||||||.|||||||||||||||||.||.|||: :
  Rat   129 DLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRK-K 192

  Fly   196 SRSRSPGRRRGSRSRSRSPGRRGGGRGDGVGGGNYLNNERDNMRGNDRGNDRDRRKGG 253
            .||||..|.|.||||.|.   ||||.|.|.|||          |..||...|||.:.|
  Rat   193 HRSRSRSRERRSRSRDRG---RGGGGGGGGGGG----------RERDRRRSRDRERSG 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	24/25 (96%)
		RRM_U2AF35	43..148	CDD:240982	75/104 (72%)
		zf-CCCH	151..177	CDD:279036	24/25 (96%)
U2af1	NP_001037756.1	zf-CCCH	13..39	CDD:395517	24/25 (96%)
		RRM_U2AF35	43..146	CDD:409954	75/104 (72%)
		zf-CCCH	149..175	CDD:395517	24/25 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341698
Domainoid	1	1.000	94	1.000	Domainoid score	I7297
eggNOG	1	0.900	-	-		E1_KOG2202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14345
Inparanoid	1	1.050	374	1.000	Inparanoid score	I2031
OMA	1	1.010	-	-		QHG56320
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	1	1.000	-	-		FOG0002537
OrthoInspector	1	1.000	-	-		otm45845
orthoMCL	1	0.900	-	-		OOG6_101418
Panther	1	1.100	-	-	LDO	PTHR12620
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.810