DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2af38 and CG3294

DIOPT Version :9

Sequence 1:	NP_001259814.1	Gene:	U2af38 / 33201	FlyBaseID:	FBgn0017457	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_608857.2	Gene:	CG3294 / 33677	FlyBaseID:	FBgn0031628	Length:	456	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	67/279 - (24%)
Similarity:	123/279 - (44%)	Gaps:	32/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAK-------S 61
            :|..:..|..::..|.|:.:...||:|..|:..|.:|...:.:|:::.:.:.....:       |
  Fly   156 HLLRVMETHPEERACEFFSRTNCCRYGHACTFNHRRPMLGRILLIRHFFNHSMLQKRCTHKEYAS 220

  Fly    62 ADGSHLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAE 126
            |: .||  .:::::::..||.||.||..|.. |:|.|.......|..:||.|:|::::.||..|.
  Fly   221 AE-EHL--ELTEQDLRHDYDEFFNDVVEELR-KFGTIVNFRTVRNTLEHLRGHVFVEYTNERSAL 281

  Fly   127 KAANDLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHL--KP---ISRELRRY 186
            :|..:|..|::..:.:..|.|.:..:|.|.|......:|.:...|.::||  .|   .:.|| .|
  Fly   282 RAFTNLQGRYYASKRLNVEFSNLRTWRGAVCGLSLTRKCPKGNDCGYLHLFGNPNNLFNTEL-EY 345

  Fly   187 LYSRRRRARSRSRSPGRRRGSRSRSRSPGRR-----------GGGRGDGVGGGNYLNNERDNMRG 240
            ....|...|| |::|..:..|.......||.           ...:..|..|.:..||::.|...
  Fly   346 TSGPRSERRS-SQTPTAKTPSWDEHSEHGRNWRWSASPEVELENSKDLGNRGRDLKNNQQRNHHS 409

  Fly   241 ---NDRGNDRDRRKGGGGG 256
               :||.:.|.:|:....|
  Fly   410 RSRSDRSSVRSKREHSSSG 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	7/25 (28%)
		RRM_U2AF35	43..148	CDD:240982	27/111 (24%)
		zf-CCCH	151..177	CDD:279036	7/27 (26%)
CG3294	NP_608857.2	tolA_full	<28..>123	CDD:274303
CG3294	NP_608857.2	RRM_SF	197..303	CDD:302621	27/109 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2202
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1692
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800