DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2af38 and Zrsr1

DIOPT Version :9

Sequence 1:	NP_001259814.1	Gene:	U2af38 / 33201	FlyBaseID:	FBgn0017457	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_035793.1	Gene:	Zrsr1 / 22183	MGIID:	98885	Length:	428	Species:	Mus musculus

Alignment Length:	269	Identity:	85/269 - (31%)
Similarity:	134/269 - (49%)	Gaps:	33/269 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGSHLVANV--SDE 74
            ||.:.:|.||.|.||||.|:||||.|:.||.|.|:|:::::..........|.....||:  |:|
Mouse   157 EKYRPSCPFYNKTGACRFGNRCSRKHDFPTSSPTLLVKSMFTTFGMEQCRRDDYDSDANLEYSEE 221

  Fly    75 EMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAANDLNNRWFGG 139
            |..:.:.:|:.||..|.:: .|::.:..|..||..||.||||:::::|.:.:.|.:..|.||:.|
Mouse   222 ETYQQFLDFYHDVLPEFKN-VGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAG 285

  Fly   140 RPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHL--KPIS--RELRRYLY------------ 188
            |.:..|..|||.::.|.|..:||.:|.:...|||:|:  .|.:  ||..|.:|
Mouse   286 RQLQCEFCPVTRWKVAICGLFEMQKCPKGKHCNFLHVFRNPNNEFREANRDIYMSPPAWTGSSGK 350

  Fly   189 --SRRRR--------ARSRSRSPGRRRGSRSRSRSPGRRGGGRGDGVGGGNYLNNERDNMRGNDR 243
              .||.|        ::|||...|....|: |:|...|:...|..........::||.:.|   |
Mouse   351 NSDRRERKDHHEEYYSKSRSYHSGSYHSSK-RNRESERKSPHRWKKSHKQTTKSHERHSSR---R 411

  Fly   244 GNDRDRRKG 252
            |.:.|...|
Mouse   412 GREEDSSPG 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	15/25 (60%)
		RRM_U2AF35	43..148	CDD:240982	31/106 (29%)
		zf-CCCH	151..177	CDD:279036	9/27 (33%)
Zrsr1	NP_035793.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51
		zf-CCCH	158..183	CDD:279036	14/24 (58%)
		RRM_U2AFBPL	190..294	CDD:240984	30/104 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..428		19/86 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820