DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2af38 and U2AF1L4

DIOPT Version :9

Sequence 1:	NP_001259814.1	Gene:	U2af38 / 33201	FlyBaseID:	FBgn0017457	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_659424.2	Gene:	U2AF1L4 / 199746	HGNCID:	23020	Length:	202	Species:	Homo sapiens

Alignment Length:	157	Identity:	84/157 - (53%)
Similarity:	95/157 - (60%)	Gaps:	41/157 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGS 65
            |||||||||||||||||||||||||.|||||||||:||||||||
Human     1 MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQ--------------------- 44

  Fly    66 HLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAAN 130
                                :||.|.::|||||||||||||||||||||||:|||.|.|.|:|..
Human    45 --------------------EVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVA 89

  Fly   131 DLNNRWFGGRPVYSELSPVTDFREACC 157
            :|:||||.|:.|:..:..|.......|
Human    90 ELSNRWFNGQAVHGNVPEVASATSCIC 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2af38	NP_001259814.1	zf-CCCH	13..39	CDD:279036	23/25 (92%)
		RRM_U2AF35	43..148	CDD:240982	42/104 (40%)
		zf-CCCH	151..177	CDD:279036	1/7 (14%)
U2AF1L4	NP_659424.2	zf-CCCH	13..39	CDD:279036	23/25 (92%)
U2AF1L4	NP_659424.2	RRM_SF	<41..102	CDD:302621	43/101 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147840
Domainoid	1	1.000	94	1.000	Domainoid score	I7476
eggNOG	1	0.900	-	-		E1_KOG2202
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1692
OMA	1	1.010	-	-		QHG56320
OrthoDB	1	1.010	-	-		D1340384at2759
OrthoFinder	1	1.000	-	-		FOG0002537
OrthoInspector	1	1.000	-	-		otm41715
orthoMCL	1	0.900	-	-		OOG6_101418
Panther	1	1.100	-	-	O	PTHR12620
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.670