DRSC/TRiP Functional Genomics Resources

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Protein Alignment BIRC5 and Diap2

DIOPT Version :9

Sequence 1:NP_001012271.1 Gene:BIRC5 / 332 HGNCID:593 Length:165 Species:Homo sapiens
Sequence 2:NP_477127.1 Gene:Diap2 / 36748 FlyBaseID:FBgn0015247 Length:498 Species:Drosophila melanogaster


Alignment Length:94 Identity:25/94 - (26%)
Similarity:39/94 - (41%) Gaps:29/94 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    14 LKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIGPGT 78
            |:.:|:.|||:||   ....||:.:|:|||.:.   |..|..:|.:|...:..||.:|:..    
  Fly   112 LEANRLVTFKDWP---NPNITPQALAKAGFYYL---NRLDHVKCVWCNGVIAKWEKNDNAF---- 166

Human    79 VAYACNTSTLGGRGGRITREEHKKHSSGC 107
                               ||||:....|
  Fly   167 -------------------EEHKRFFPQC 176

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BIRC5NP_001012271.1 BIR 18..110 CDD:279047 24/90 (27%)
Diap2NP_477127.1 BIR 12..78 CDD:237989
BIR 112..181 CDD:197595 25/94 (27%)
BIR 213..281 CDD:237989
UBA_IAPs 320..363 CDD:270506
zf-C3HC4_3 447..492 CDD:290631
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165140729
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R141
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.770

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