DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Amnionless and amn

DIOPT Version :9

Sequence 1:	NP_001259813.1	Gene:	Amnionless / 33199	FlyBaseID:	FBgn0025686	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	XP_021330475.1	Gene:	amn / 793454	ZFINID:	ZDB-GENE-060810-59	Length:	538	Species:	Danio rerio

Alignment Length:	507	Identity:	113/507 - (22%)
Similarity:	198/507 - (39%)	Gaps:	83/507 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ALATKWYGGGMDFNDPTAWLDDHLPCAQDLVVFPEYYPALLPLPEDISIDGLVFPREGAILLAEE 82
            ||..:|. ...:|.:.|.|....:||..|.|.|.......:.:....:|.|:..|.:|.::||..
Zfish    82 ALYKQWI-PDTNFENATNWDKGSVPCGNDQVEFLANRKVSVYVETAHTITGMSLPVDGELILASG 145

  Fly    83 STITFGSDKQPSCESDENKAYLKPPKSSKWFDPGTWT------DKSKEFSTFTPELERIPCDDEQ 141
            :..|......|.|.|... |..|..:|.|||||..|.      |..:....|:...|.:||.::.
Zfish   146 AGFTVREGGDPGCGSGVT-AQFKDSESLKWFDPSLWVAATTIDDLHRGTFQFSVHEESVPCQNDD 209

  Fly   142 VIIKGHGPLAFDLENVQYLRLGQLILAGSSI-SKTYLEQLISRDLGQFLFYNAEYVQVEYYR-GE 204
            |:.:.......::.:...:.:..:.:.|... |.:...|.:|...|:..|:....:.:.... ||
Zfish   210 VVFRDATSFRVEISSDHDVPVKSVSVLGKKFTSSSEFSQYLSSSSGKLQFHGTATISISSSGCGE 274

  Fly   205 LCGCHKDFERLLEPVCHNVQEQCETPHCLSPVRPLGSCCLICGAI--LSTPTTHCTEGSRKELVA 267
            :.||..|..|..|.:|.||  :|:|..|..|:..||.||.:|||:  :...::...|..|:.|..
Zfish   275 ISGCICDNSRNREKICANV--RCDTLECKKPLHALGHCCNVCGALVYVQFSSSFNFESYRQRLQH 337

  Fly   268 QISNLISQESLK---DQIGLHVEFVGSQKFGNC--LQAVVTDRH------KYSERSLEFLQQNEH 321
            ...|.....|::   .::......:|...||..  :|.::.|:.      ..:|.....:.::.|
Zfish   338 LFLNTDKYRSVQMAMSKVSREQRLLGVIPFGATQEIQVLLLDQKTGLESGNLAETLARDIMKDVH 402

  Fly   322 NWNKTGTTLKVSGRPYNPNVSFSS---------IV--LILFCMALVGLVSVVILAHFMPENPYLN 375
            |   .|:.:.:|...:..:...||         :|  .:|.|:.::||::..||.:    ...:.
Zfish   403 N---HGSNVGISSAEFQASSGASSSDVAGNSAGVVAGAVLGCLVILGLLAGFILLY----RRGVV 460

  Fly   376 RIPQWIHDPRLWRWRHLGLRLRRNLLFNRFDNGGAEGGSSEGGASGVDRLGIMAYDPESGEVRER 440
            ::|:....|.|.:||:                     ||..|               |.|...:.
Zfish   461 KLPRMPSIPSLSKWRN---------------------GSDIG---------------ELGGPMDH 489

  Fly   441 AFDNPMFEQGGALEEAAKESQEQDEILSVPKMETGDLDARSVVDEQELTEIN 492
            .||||||::...:.| ..|....:.:.||...::|......|.||   |:.|
Zfish   490 GFDNPMFDKPTMMPE-QPELYGSETMNSVVLTKSGVHFVNPVYDE---TDFN 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Amnionless	NP_001259813.1	Amnionless	21..448	CDD:291494	100/458 (22%)
amn	XP_021330475.1	Amnionless	84..532	CDD:317263	107/495 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7373
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I5045
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D356731at33208
OrthoFinder	1	1.000	-	-		FOG0008021
OrthoInspector	1	1.000	-	-		oto41435
orthoMCL	1	0.900	-	-		OOG6_108642
Panther	1	1.100	-	-	LDO	PTHR14995
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5974
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.970