DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11601 and Aig1

DIOPT Version :9

Sequence 1:	NP_001285545.1	Gene:	CG11601 / 33197	FlyBaseID:	FBgn0031244	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_079722.1	Gene:	Aig1 / 66253	MGIID:	1913503	Length:	262	Species:	Mus musculus

Alignment Length:	227	Identity:	79/227 - (34%)
Similarity:	122/227 - (53%)	Gaps:	25/227 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LLAAAQFSY-GIYFHYFRVHWPTDLLDEDELKARWGGKFKYLTFLDVILQAIYHSLALLNDLF-- 107
            |..|...|| .|..:|..:..|:        ...:||.:|:|||:|:::||::..:.:|.||.
Mouse     9 LRVAILLSYCSILCNYKAIEMPS--------HQTYGGSWKFLTFIDLVIQAVFFGICVLTDLSSL 65

  Fly   108 ---GDNNVSGDSKSMLR---SVRDYVFAAFAFPVAHNVCLSFWVIYVWDRELIFPSALDAIFPSW 166
               |..|  .:.:..||   |:||:..|..||||...|...||.||.:|||:|:|..||...|.|
Mouse    66 LTRGSGN--QEQERQLRKLISLRDWTLAVLAFPVGVFVVAVFWTIYAYDREMIYPRLLDNFIPGW 128

  Fly   167 LNHVVHTNVALLAIMDLFTCFRRYPSRLAGITGNVSFILLYIIWLHIVRYFSGEWVYPILEVLPA 231
            |||.:||.|....::::.|...:||||.:|:....:|.:.||:|:..:.:.:|.||||.||.:.:
Mouse   129 LNHGMHTTVLPFILIEMRTSHHQYPSRSSGLAAICTFSVGYILWVCWIHHVTGMWVYPFLEHIGS 193

  Fly   232 YLRYVFL---ALLVGFNLVCYLLGEFANNVVW 260
            ..|.:|.   .:|:.|   .|||||..|:.:|
Mouse   194 GARIIFFGSTTILMNF---LYLLGEVLNSYIW 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11601	NP_001285545.1	Far-17a_AIG1	40..257	CDD:282588	77/222 (35%)
Aig1	NP_079722.1	Far-17a_AIG1	12..219	CDD:368096	76/219 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847207
Domainoid	1	1.000	166	1.000	Domainoid score	I3859
eggNOG	1	0.900	-	-		E1_KOG3989
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I4084
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49430
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001424
OrthoInspector	1	1.000	-	-		otm42705
orthoMCL	1	0.900	-	-		OOG6_102603
Panther	1	1.100	-	-	O	PTHR10989
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X992
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760