DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11601 and AIG1

DIOPT Version :9

Sequence 1:	NP_001285545.1	Gene:	CG11601 / 33197	FlyBaseID:	FBgn0031244	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_001353273.1	Gene:	AIG1 / 51390	HGNCID:	21607	Length:	285	Species:	Homo sapiens

Alignment Length:	285	Identity:	84/285 - (29%)
Similarity:	130/285 - (45%)	Gaps:	69/285 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LLAAAQFSY-GIYFHYFRVHWPTDLLDEDELKARWGGKFKYLTFLDV------------------ 91
            |..|...|| .|..:|..:..|:        ...:||.:|:|||:|:
Human     9 LRMAILLSYCSILCNYKAIEMPS--------HQTYGGSWKFLTFIDLMESHSVTRLECSGTISAH 65

  Fly    92 -----------------------------ILQAIYHSLALLNDLF-----GDNNVSGDSK-SMLR 121
                                         ::||::..:.:|.||.     |..|...:.: ..|.
Human    66 CNLCLLCSSYSPASASRVAGTTGVCHHARVIQAVFFGICVLTDLSSLLTRGSGNQEQERQLKKLI 130

  Fly   122 SVRDYVFAAFAFPVAHNVCLSFWVIYVWDRELIFPSALDAIFPSWLNHVVHTNVALLAIMDLFTC 186
            |:||::.|..||||...|...||:||.:|||:|:|..||...|.||||.:||.|....::::.|.
Human   131 SLRDWMLAVLAFPVGVFVVAVFWIIYAYDREMIYPKLLDNFIPGWLNHGMHTTVLPFILIEMRTS 195

  Fly   187 FRRYPSRLAGITGNVSFILLYIIWLHIVRYFSGEWVYPILEVLPAYLRYVFL---ALLVGFNLVC 248
            ..:||||.:|:|...:|.:.||:|:..|.:.:|.||||.||.:....|.:|.   .:|:.|   .
Human   196 HHQYPSRSSGLTAICTFSVGYILWVCWVHHVTGMWVYPFLEHIGPGARIIFFGSTTILMNF---L 257

  Fly   249 YLLGEFANNVVWGPEFKLLNQQKLK 273
            |||||..||.:|..: |.:.::|.|
Human   258 YLLGEVLNNYIWDTQ-KSMEEEKEK 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11601	NP_001285545.1	Far-17a_AIG1	40..257	CDD:282588	78/267 (29%)
AIG1	NP_001353273.1	Far-17a_AIG1	12..266	CDD:309749	77/264 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156795
Domainoid	1	1.000	167	1.000	Domainoid score	I3862
eggNOG	1	0.900	-	-		E1_KOG3989
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4081
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49430
OrthoDB	1	1.010	-	-		D1482757at2759
OrthoFinder	1	1.000	-	-		FOG0001424
OrthoInspector	1	1.000	-	-		otm40630
orthoMCL	1	0.900	-	-		OOG6_102603
Panther	1	1.100	-	-	O	PTHR10989
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X992
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770