| Sequence 1: | NP_523443.1 | Gene: | smo / 33196 | FlyBaseID: | FBgn0003444 | Length: | 1036 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_742032.2 | Gene: | Fzd2 / 64512 | RGDID: | 71012 | Length: | 570 | Species: | Rattus norvegicus |
| Alignment Length: | 529 | Identity: | 124/529 - (23%) |
|---|---|---|---|
| Similarity: | 217/529 - (41%) | Gaps: | 120/529 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 118 HTEKE-LNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCRI 181
Fly 182 LYNTTFF--PKFLRCNE-------------------------TLFPTKCTNGARG---------- 209
Fly 210 ------------------------MKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDD 250
Fly 251 EHRQIHK-LIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSGS 314
Fly 315 REDIVCR----KDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRA---MGHV 372
Fly 373 QDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILI 437
Fly 438 GGYFITRGMVMLFG----LKHFANDIKSTSASNKIHLIIMRMGVCALLTLVFILVAIACHVTEFR 498
Fly 499 HADEWAQSF-RQFIICKISSV-----FEEKSSCRIENRPSVGVLQLHLLCLFSSGIVMSTWCWTP 557
Fly 558 SSIETWKRY 566 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| smo | NP_523443.1 | CRD_SMO | 86..221 | CDD:143560 | 31/164 (19%) |
| Frizzled | 246..568 | CDD:279827 | 90/339 (27%) | ||
| Fzd2 | NP_742032.2 | CRD_FZ2 | 40..166 | CDD:143573 | 22/101 (22%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 166..194 | 5/27 (19%) | |||
| 7tmF_FZD2 | 239..568 | CDD:320373 | 90/354 (25%) | ||
| TM helix 1 | 249..273 | CDD:320373 | 6/24 (25%) | ||
| TM helix 2 | 282..303 | CDD:320373 | 2/20 (10%) | ||
| TM helix 3 | 333..355 | CDD:320373 | 7/21 (33%) | ||
| TM helix 4 | 376..392 | CDD:320373 | 10/15 (67%) | ||
| TM helix 5 | 414..437 | CDD:320373 | 7/22 (32%) | ||
| TM helix 6 | 468..490 | CDD:320373 | 8/21 (38%) | ||
| TM helix 7 | 519..544 | CDD:320373 | 6/30 (20%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 548..553 | 0/4 (0%) | |||
| PDZ-binding | 568..570 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||