DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment smo and SFRP4

DIOPT Version :9

Sequence 1:NP_523443.1 Gene:smo / 33196 FlyBaseID:FBgn0003444 Length:1036 Species:Drosophila melanogaster
Sequence 2:NP_003005.2 Gene:SFRP4 / 6424 HGNCID:10778 Length:346 Species:Homo sapiens


Alignment Length:147 Identity:37/147 - (25%)
Similarity:59/147 - (40%) Gaps:25/147 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 VRRARCYPTSNATNTCFGSKLPYELSSLDLTDFH-TEKELNDKLNDYYALKHVPKCWAAIQPFLC 148
            ||.|.|    .|........:|:.::.:.....| |::.....:..|..|..| .|.|.::.|||
Human    19 VRGAPC----EAVRIPMCRHMPWNITRMPNHLHHSTQENAILAIEQYEELVDV-NCSAVLRFFLC 78

  Fly   149 AVFKPKCEKINGEDMVYLPSYEMC---RITMEPCRILYNTTFFPKFLRCNETLFPTKCTNGARGM 210
            |::.|.|......|.: .|...:|   |...||...:||.: :|:.|.|:|             :
Human    79 AMYAPICTLEFLHDPI-KPCKSVCQRARDDCEPLMKMYNHS-WPESLACDE-------------L 128

  Fly   211 KFNGTGQCLSP-LVPTD 226
            .....|.|:|| .:.||
Human   129 PVYDRGVCISPEAIVTD 145

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
smoNP_523443.1 CRD_SMO 86..221 CDD:143560 32/138 (23%)
Frizzled 246..568 CDD:279827
SFRP4NP_003005.2 CRD_FZ 20..146 CDD:321937 36/146 (25%)
NTR_like 188..296 CDD:321963
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 292..346
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.