Protein Alignment smo and fz2

DIOPT Version :9

• Sequence 1: NP_523443.1
• Gene: smo / 33196
• FlyBaseID: FBgn0003444
• Length: 1036
• Species: Drosophila melanogaster
• Sequence 2: NP_001262037.1
• Gene: fz2 / 40090
• FlyBaseID: FBgn0016797
• Length: 806
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 138/581 - (23%)
• Similarity: 242/581 - (41%)
• Gaps: 138/581 - (23%)

  Fly   100 CFGSKLPYELSSL-DLTDFHTEKELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDM 163
            |.|  :.|.::|. :..:..|:.|...:::.::.|..: ||...::.|||:::.|.|.    ||
  Fly    72 CRG--IGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEI-KCSPDLKFFLCSMYTPICL----ED- 128

  Fly   164 VYLPSYEMCRITMEPCR-----ILYNTTF-FPKFLRCNE-----------------TLFPTKCTN 205
             |.....:||...|..|     |:...:| :|:.:.|..                 |...:..::
  Fly   129 -YHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSS 192

  Fly   206 GARGMKFNGTG----------------------------------------------------QC 218
            |..|...:|:|                                                    .|
  Fly   193 GGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSC 257

  Fly   219 LSPLV----------PTDTSASYYP-------------GIEGCGVRCKDPLYTDDEHRQIHKLIG 260
            .|||:          .:.....::|             |:..||:.||.|.:::||.......|.
  Fly   258 RSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIA 322

  Fly   261 -WAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWL----LQFTSGSREDIVC 320
             |:| :|..|.|..::||.||.:.. |||...:.:::.|:.:..||:|    ||     .|:|.|
  Fly   323 LWSG-LCFCSTLMTLTTFIIDTERF-KYPERPIVFLSACYFMVAVGYLSRNFLQ-----NEEIAC 380

  Fly   321 RKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRA-MGHVQDRIDKKGSYFH 384
              ||.|.....|...  ||.::|:|.|:|..|..:|:|.|::.|...| :....:.|.|...|||
  Fly   381 --DGLLLRESSTGPH--SCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFH 441

  Fly   385 LVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGYFITRGMVML 449
            |.||.:|.|.::..:..|.|||:.|:|||:||.:|.......:|.||...::||..|:..|.|.|
  Fly   442 LAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSL 506

  Fly   450 FGLKHFANDIKSTSA---SNKIHLIIMRMGVCALLTLVFILVAIACHVTEFRHADEWAQSFRQFI 511
            |.::..........|   ::|:..:::|:|:.::|..|...:.|.|::.|..:.::|.::    :
  Fly   507 FRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKA----L 567

  Fly   512 ICKISSVFEEKSSCRIENRPSVGVLQLHLLCLFSSGIVMSTWCWTPSSIETWKRYIRKKCG 572
            .|..:.|   |...:   :|...||.|......:.||....|.|:..::|:|:|:.|:..|
  Fly   568 ACPCAQV---KGPGK---KPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLG 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smo	NP_523443.1	CRD_SMO	86..221	CDD:143560	31/196 (16%)
		Frizzled	246..568	CDD:279827	95/330 (29%)
fz2	NP_001262037.1	CRD_FZ5_like	63..182	CDD:143565	25/118 (21%)
		Frizzled	308..618	CDD:279827	95/330 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438648
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509772at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11309
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850