Sequence 1: | NP_523443.1 | Gene: | smo / 33196 | FlyBaseID: | FBgn0003444 | Length: | 1036 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_695217.1 | Gene: | Fzd9 / 266608 | RGDID: | 628817 | Length: | 592 | Species: | Rattus norvegicus |
Alignment Length: | 579 | Identity: | 134/579 - (23%) |
---|---|---|---|
Similarity: | 240/579 - (41%) | Gaps: | 98/579 - (16%) |
- Green bases have known domain annotations that are detailed below.
Fly 100 CFGSKLP------YELSSLDLTDFHTEK-ELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKC-E 156
Fly 157 KINGEDMVYLPSYEMCRITMEPCRILYNTTFFPKFLRC------------------NETLFPTKC 203
Fly 204 TNG-----------------ARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGVRCKDPLYTDDE 251
Fly 252 HRQIHKLIGWA---GSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFLIACVGWLLQFTSG 313
Fly 314 SREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFLTYAWHWRA---MGHVQDR 375
Fly 376 IDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINHSMRAGLLLGPLCGVILIGGY 440
Fly 441 FITRGMVMLFGLKHFANDIKSTSASN--KIHLIIMRMGVCALLTLVFILVAIACHVTEFRHADEW 503
Fly 504 -AQSFRQFIICKISSVFEEKSSCRIE--NRPSVGVLQLHLLCLFSSGIVMSTWCWTPSSIETWKR 565
Fly 566 --YIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDKGR--------LSITLYNTHTDP 614 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
smo | NP_523443.1 | CRD_SMO | 86..221 | CDD:143560 | 33/163 (20%) |
Frizzled | 246..568 | CDD:279827 | 87/334 (26%) | ||
Fzd9 | NP_695217.1 | CRD_FZ9 | 36..162 | CDD:143572 | 24/123 (20%) |
Required for Wnt-activated receptor activity. /evidence=ECO:0000269|PubMed:12138115 | 59..173 | 24/115 (21%) | |||
7tmF_FZD9 | 222..543 | CDD:320164 | 86/330 (26%) | ||
TM helix 1 | 232..256 | CDD:320164 | 7/23 (30%) | ||
TM helix 2 | 265..286 | CDD:320164 | 2/20 (10%) | ||
TM helix 3 | 315..337 | CDD:320164 | 9/21 (43%) | ||
TM helix 4 | 358..374 | CDD:320164 | 9/15 (60%) | ||
TM helix 5 | 396..419 | CDD:320164 | 6/22 (27%) | ||
TM helix 6 | 450..472 | CDD:320164 | 8/21 (38%) | ||
TM helix 7 | 504..529 | CDD:320164 | 6/24 (25%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 533..538 | 0/4 (0%) | |||
Required for CTNNB1 accumulation and TCF transcription factor activity. /evidence=ECO:0000269|PubMed:12138115 | 555..592 | 8/45 (18%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D509772at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.820 |