Sequence 1: | NP_523443.1 | Gene: | smo / 33196 | FlyBaseID: | FBgn0003444 | Length: | 1036 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001155966.1 | Gene: | Fzd6 / 14368 | MGIID: | 108474 | Length: | 709 | Species: | Mus musculus |
Alignment Length: | 679 | Identity: | 157/679 - (23%) |
---|---|---|---|
Similarity: | 260/679 - (38%) | Gaps: | 153/679 - (22%) |
- Green bases have known domain annotations that are detailed below.
Fly 138 KCWAAIQPFLCAVFKPKC-EKINGEDMVYLPSYEMCRITMEPCRILYNT--TFFPKFLRCN---- 195
Fly 196 -------------ETLFPTK------------C-----TNGARGMKFNGTGQCLSPLVPTDTSAS 230
Fly 231 YYPGIEGCGVRCKDPLYTDDEHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYI 295
Fly 296 NLCFLIACVGWLLQFTSGSREDIVCRK-DGTLRHSEPT--AGENLSCIVIFVLVYYFLTAGMVWF 357
Fly 358 VFLTYAW------HWRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVG 416
Fly 417 YINHSMRAGLLLGPLCGVILIGGYFITRGMVMLFGLKHFANDIKSTSAS-NKIHLIIMRMGVCAL 480
Fly 481 LTLVFILVAIACHVTEFRHADEWAQSF-----RQFIICKISSVFEEKSSCRIENRPSVGVLQLHL 540
Fly 541 LCLFSSGIVMSTWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDKGRLSI 605
Fly 606 TLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMALTGAATGNSSSHGPR------ 664
Fly 665 KNSLDSEISVSVRHVSVESRRNSVDSQVSVK--IAEMKTKVASRSR--GKHGGSSS------NRR 719
Fly 720 TQRRRDYIAAATGKSSRRRESSTSVESQV 748 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
smo | NP_523443.1 | CRD_SMO | 86..221 | CDD:143560 | 32/119 (27%) |
Frizzled | 246..568 | CDD:279827 | 86/336 (26%) | ||
Fzd6 | NP_001155966.1 | CRD_FZ6 | 20..146 | CDD:143559 | 22/81 (27%) |
7tmF_FZD6 | 188..508 | CDD:320160 | 86/337 (26%) | ||
TM helix 1 | 198..222 | CDD:320160 | 8/23 (35%) | ||
TM helix 2 | 231..252 | CDD:320160 | 3/20 (15%) | ||
TM helix 3 | 283..305 | CDD:320160 | 10/21 (48%) | ||
TM helix 4 | 326..342 | CDD:320160 | 8/15 (53%) | ||
TM helix 5 | 364..387 | CDD:320160 | 5/22 (23%) | ||
TM helix 6 | 418..440 | CDD:320160 | 8/21 (38%) | ||
TM helix 7 | 469..494 | CDD:320160 | 5/28 (18%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 498..503 | 0/4 (0%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 583..709 | 23/89 (26%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |