Protein Alignment smo and Corin

DIOPT Version :10

• Sequence 1: NP_523443.1
• Gene: smo / 33196
• FlyBaseID: FBgn0003444
• Length: 1036
• Species: Drosophila melanogaster
• Sequence 2: XP_061506966.1
• Gene: Corin / 1277217
• VectorBaseID: AGAMI1_007116
• Length: 1432
• Species: Anopheles gambiae
• Alignment Length: 277
• Identity: 61/277 - (22%)
• Similarity: 94/277 - (33%)
• Gaps: 70/277 - (25%)

  Fly     6 FPRMPNIMMFLEVAILCLWVVADASASSAKFG----STTPASAQQSDVELEPINGTLNYRLYAKK 66
            |...|.| .|:...|....|.|....|||..|    |:.|||.....|...|....|:   .|..
Mosquito   770 FNAYPTI-KFVNQTITRTAVPASQPGSSAVGGSGAVSSVPASGSGQSVAGSPGRTALD---VAGG 830

  Fly    67 GRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTCFGSKLPYELSSL-DLTDFHTEKELNDKLNDY 130
            .|.|:....|:            |.|.  ....|...::||..:.. :......:.|...:::.:
Mosquito   831 FRGDRNPAPGV------------CLPV--IVKFCQQHRVPYNYTVFPNYIGHFGQPEAQIEIDLF 881

  Fly   131 YALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCRILYNT--TFFPKFLR 193
            .||..| :|:..:..|||::|.|||   ........|...:|..||..|...::.  ...|::||
Mosquito   882 EALVDV-QCYELVPLFLCSLFVPKC---GNSGATVPPCKSLCTETMRRCSFFFDVFGLELPEYLR 942

  Fly   194 CN-------------------ETLF----PTKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGI 235
            |:                   |::.    |..||......:     :|    :|.|.....:
Mosquito   943 CSIFNDAVSDQEECVGMAEYKESIIRSRRPMACTGFLCDKR-----RC----IPNDWKCDGH--- 995

  Fly   236 EGCGVRCKDPLYTDDEH 252
                |.|:|  .||:.|
Mosquito   996 ----VDCQD--QTDEAH 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smo	NP_523443.1	CRD_SMO	86..221	CDD:143560	31/160 (19%)
		7tmF_SMO_homolog	245..568	CDD:320158	3/8 (38%)
		TM helix 1	254..279	CDD:320158
		TM helix 2	289..310	CDD:320158
		TM helix 3	340..366	CDD:320158
		TM helix 4	382..398	CDD:320158
		TM helix 5	420..449	CDD:320158
		TM helix 6	471..498	CDD:320158
		TM helix 7	529..554	CDD:320158
Corin	XP_061506966.1	None