Protein Alignment CG17075 and Zdhhc1

DIOPT Version :10

• Sequence 1: NP_608508.1
• Gene: CG17075 / 33191
• FlyBaseID: FBgn0031239
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: NP_780369.1
• Gene: Zdhhc1 / 70796
• MGIID: 1918046
• Length: 484
• Species: Mus musculus
• Alignment Length: 556
• Identity: 169/556 - (30%)
• Similarity: 239/556 - (42%)
• Gaps: 165/556 - (29%)

  Fly    94 DVQHRKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGLYLVHIAS 158
            ::|.::.|| :|...|.|||||..||:.|.|.|..:.||:|..........|..:..::..|:..
Mouse    30 ELQGQRSRR-NGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVV 93

  Fly   159 HLTALLTDPADKELRRVHRNDRI----VPEFDRSKHSHVIENGRCHLCNIRTSSNRTKHCSVCNK 219
            ||||:..||||..:|     |:.    :|.|:||:|:||||:..|:||::..|: |:||||.|||
Mouse    94 HLTAVSIDPADANVR-----DKSYSGPLPIFNRSQHAHVIEDLHCNLCDVDVSA-RSKHCSACNK 152

  Fly   220 CVGKFDHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTES 284
            ||..|||||||||:|:|.|||..||..|.||::..|::|  :||..||       :.|
Mouse   153 CVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLV--LVATYVF-------VEF------- 201

  Fly   285 SHTIESGDFINITLSLSNGTMMLIEQHTSEEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASA 349
                    |:|.....:|....:::.||       ::|                  |..:
Mouse   202 --------FVNPMRLRTNQHFEVLKNHT-------DVW------------------FVFL----- 228

  Fly   350 TRPGISPTNHTETQ-PVVTGIGLNETIFMFLLGVLGLLAAVSAGLLLHLCFFHIYISFLGLTTYE 413
                  |....||| |.:..:..       ||.:||||   |..||.||..||||:.:..|||||
Mouse   229 ------PAAPVETQAPAILALAA-------LLILLGLL---STALLGHLLCFHIYLMWHKLTTYE 277

  Fly   414 YIRNHRQAQDAK-TKQLLEGAP-GVRAPKNGNVH---FSASLPEPH----------NPSKSLPGG 463
            ||..||.||:|| |.:.||..| .||:.:....:   ||...|||.          |||:.|...
Mouse   278 YIVQHRPAQEAKETHKELESCPRKVRSIQEMEFYMRTFSHVRPEPSGQARTAALNANPSQFLATQ 342

  Fly   464 QQLYCCSSAPHPSQHSQESVG-------QTEQSLRLHCCASSREFHQSGQAIYVCSLLEEAVPQI 521
            .|:    ..|.||  |.:::.       |.::..|::      ...:||       :|:..:|..
Mouse   343 GQV----EPPLPS--SSDTLALPPRIQPQKKRKRRVY------RLPRSG-------VLDRELPLP 388

  Fly   522 QV-EPDTLSSFHCCSSFAASSLQRRVSLAKGSLISAEPRHLRPATYLQYTEQCTLCTFRLRRGSG 585
            :: |..|.|              ||.|.:..| .||.|.|
Mouse   389 RLRETGTPS--------------RRSSSSSDS-TSASPVH------------------------- 413

  Fly   586 PGTGSSGAVSSAGGSSSTRTLTSQTGGSSASATAAG 621
             ..||:||..||...|......:||...||:..|.|
Mouse   414 -AGGSAGAYYSASAESMEEIPVAQTRLGSAALGAPG 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_608508.1	DHHC	199..>282	CDD:396215	40/82 (49%)
Zdhhc1	NP_780369.1	Mediates interaction with STING1. /evidence=ECO:0000250|UniProtKB:Q8WTX9	1..268		105/314 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		1/7 (14%)
		DHHC	126..281	CDD:396215	78/225 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..415		22/133 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..484		2/5 (40%)