DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17075 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_001034432.1	Gene:	Zdhhc14 / 499014	RGDID:	1565877	Length:	489	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	123/536 - (22%)
Similarity:	193/536 - (36%)	Gaps:	156/536 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 PLHLCRLSQLVSYQSNIADVQHRK-------------GRR---LHGLQLPLHPLQIFGWLVLLLF 124
            |:..|..||:.::.|:..:..|:|             ||.   .:|..:......:| :|.|:|.
  Rat     8 PMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVF-YLTLILI 71

  Fly   125 GVASYWVLIPAFHARIQG-------PLYGLITGLYLVHIASHLTALLTDP-----------ADKE 171
            .|.|  .|..||..|...       |:.|.|  |:...:.:.|....:||           ||.|
  Rat    72 LVTS--GLFFAFDCRYLAEKITPAIPVVGGI--LFFFVMGTLLRTSFSDPGVLPRATPDEAADLE 132

  Fly   172 LRRVHRND------RIVPEFDRSKHSHVIENGR------CHLCNIRTSSNRTKHCSVCNKCVGKF 224
            .:....|.      |..|   |:|  .||.||:      |..|.| ....|..|||:|:.||.:|
  Rat   133 RQIDIANGTSSGGYRPPP---RTK--EVIINGQTVKLKYCFTCKI-FRPPRASHCSLCDNCVEQF 191

  Fly   225 DHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWL-SFYWCPTESSHTI 288
            ||||.|:.:|:|.|||..|.|.::|....|:.|.|.|:..::....|..:| :....|......:
  Rat   192 DHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVIHRSQQKGFLDALKDSPASVLEAV 256

  Fly   289 ESGDFINITLSLSN-GTMMLIEQHTSEEDVHQEMWDEEQ--------------ANMTISTL---- 334
            .....:...:.||. .|.::....|:.||: :..|..::              .|..::..
  Rat   257 ICFFSVWSIIGLSGFHTYLISSNQTTNEDI-KGSWSNKRGKENYNPYSYGNIFTNCCVALCGPIS 320

  Fly   335 PTLLENFTAIIEASATRP-----GISPTNHTETQPVVTGIG--LNETIFMFLLGVLGLLAAVSAG 392
            |:|::. ...|:....:|     ||:....|::|..:....  :..|.|        :|.|.:..
  Rat   321 PSLIDR-RGYIQPDTPQPAAPSNGITMYGATQSQSDMCDQDQCIQSTKF--------VLQAAATP 376

  Fly   393 LLLHLCFFHIYISFLGLTTYEYIRNHRQAQDAKTKQLLE--GAPGVRAPKNGNVHFSASLPEPHN 455
            ||                         |::.:.|.:.|.  |.||:..|     ..|.:|.:|..
  Rat   377 LL-------------------------QSEPSLTSEELHMPGKPGLGTP-----CASLTLGQPTP 411

  Fly   456 PSKSLP------------------GGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFH 502
            || |:|                  ||.|......||.|.:    .:|....      .|.||..|
  Rat   412 PS-SMPNLATEATLSDIMPLKDEHGGHQFLTPDEAPSPPR----MLGAGSP------LAHSRTMH 465

  Fly   503 QSGQAIYVCSLLEEAV 518
            ..|.|.. .||.|::|
  Rat   466 MLGLASQ-DSLHEDSV 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	30/83 (36%)
Zdhhc14	NP_001034432.1	DHHC	164..287	CDD:396215	37/124 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810