Protein Alignment CG17075 and app

DIOPT Version :10

• Sequence 1: NP_608508.1
• Gene: CG17075 / 33191
• FlyBaseID: FBgn0031239
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 930
• Identity: 179/930 - (19%)
• Similarity: 278/930 - (29%)
• Gaps: 354/930 - (38%)

  Fly    90 SNIADVQH--RK-----GRR---LHGLQLPLHPLQIFGWLVLLLFGVASYW------VLIPAFHA 138
            ||:|..|.  ||     ||.   ..||.:......:|....:|:.|.::.:      .|..:.:.
  Fly    10 SNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP 74

  Fly   139 RIQGPLYGLITGLYLVHIASHLTALLTDP------ADKELRRVHR-----NDRIVPEF---DRSK 189
            .|  |:.|.:  ||...::|.|....|||      ::.|...:.:     |....|.:   .|:|
  Fly    75 AI--PIVGAV--LYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTK 135

  Fly   190 HSHVIENGR------CHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVV 248
              .|:..|:      |..|.| ....|..|||:|:.||.:|||||.|:.:|:|.|||..|.:.:|
  Fly   136 --EVLVKGQTVKLKYCFTCKI-FRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLV 197

  Fly   249 SAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITLSLSNGTMMLIEQHTS 313
            |.....:.|.:..|..:|                                      :::.::|
  Fly   198 SLAFLAVFIFSCSVTHLV--------------------------------------LLMKKEH-- 222

  Fly   314 EEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQPVVTGIGLNETIFMF 378
                  |:::      .|...|     ||.|:
  Fly   223 ------EVFN------VIKAAP-----FTVIV--------------------------------- 237

  Fly   379 LLGVLGLLAAVSAGLLLHLCFFHIY--ISFLGLTTYEYIRNHRQAQDAKTKQLLEGAPGVRAP-K 440
                            :.:|||.|:  |...|..||....:....:|.|.....:|.|..:.| .
  Fly   238 ----------------VFICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYS 286

  Fly   441 NGNVHFSASLPEPHNPSKSLPGGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFHQSG 505
            .||:                        |                      |:||
  Fly   287 RGNI------------------------C----------------------LNCC---------- 295

  Fly   506 QAIYVCSLLEEAVPQIQVEPDTLSSFH-CCSSFAASSLQRRVSLAKGSLI-----SAEPRH---- 560
                                      | .|.....|.:.|| .:|....|     .:.|||
  Fly   296 --------------------------HILCGPMTPSLIDRR-GIATDEFIQQMQHQSSPRHALSD 333

  Fly   561 LRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSS-----------STRTLTSQTGGSS 614
            :..|:::..|.|..:...     .|.|.|.:|...|.||:.           |:.||....|..:
  Fly   334 VLSASHMVTTSQPMMGGL-----GGGGIGGAGGGISIGGAELKPRFYDESNPSSSTLEGNGGAIN 393

  Fly   615 ASATAAGNISKHQRWRRKWNCCAAVPDSPDLPND-----------LLAALTFRESEEAAAAAKLN 668
            ......||...|.            |.|.||..:           .|..|....:::...|:|..
  Fly   394 GHGNGHGNGFDHP------------PPSYDLVQNGKSRKHHQQRCSLQTLLPASAQQQFKASKHK 446

  Fly   669 AQELPIQFIRTLNGGLDQELPLKATTATPTPPRSSRLR-------YMLRLLGRYRRP------RC 720
            .::|....:..       ||........|.|...|.||       |.|.|......|      ..
  Fly   447 HKQLKQHLVAA-------ELQQHEGGPGPGPNSPSLLRSPATSSSYRLNLKRSLHLPLTPSYDDV 504

  Fly   721 RHG----AHHGIAAKEHQNIG-----GSAIKQNQIRPLQLQAAGRGYANSTATPTPPASSPSRSS 776
            ||.    .||.:.|::...||     .:|:.............|.|.::|:||.|.|.|
  Fly   505 RHSPLPLLHHHVHAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTTAPTS------ 563

  Fly   777 LESSDLSTSTSPSCGKK--ELMLLPTSVIRDDSVTTYTL-TLPPALPPPTRRKMNQTTQELAELA 838
             .|..|:|:..|...::  .|.|..:..|...:.|..|: |..|..|.||..|
  Fly   564 -VSVSLATAPPPLAPRRPSTLQLQASGAISASNSTLTTIHTTAPQAPAPTDFK------------ 615

  Fly   839 ETLGFASNLQHSQHNSQTN-SRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLR 902
                    ....|.::.:| .|..| |....|..||:   .|.|.....::.:|.    .|.|:|
  Fly   616 --------YYSPQRSTDSNLMRNYP-FPKAARGMRRQ---STMSVDSQKVNIAGY----QPLPMR 664

  Fly   903 --HHHQNLANSNSNPAKAMS 920
              :.||.:.....:|...::
  Fly   665 KPYKHQEVMFELKSPTNRLT 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_608508.1	DHHC	199..>282	CDD:396215	27/82 (33%)
app	NP_648561.2	DHHC	146..270	CDD:396215	43/230 (19%)