DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17075 and zdhhc8b

DIOPT Version :10

Sequence 1:NP_608508.1 Gene:CG17075 / 33191 FlyBaseID:FBgn0031239 Length:968 Species:Drosophila melanogaster
Sequence 2:NP_840089.3 Gene:zdhhc8b / 352941 ZFINID:ZDB-GENE-030407-3 Length:751 Species:Danio rerio


Alignment Length:976 Identity:183/976 - (18%)
Similarity:284/976 - (29%) Gaps:404/976 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 PHSLGSEDSPENIIPGEQAETNKKPLHLCRLSQLVSYQSNIADVQHRKGRRLHGLQLPLHPLQIF 116
            |:|:|....|...||...|.|                                            
Zfish     2 PNSVGKRFKPTKYIPVSTAAT-------------------------------------------- 22

  Fly   117 GWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGL-YLVHIASHLTALLTDPA-----------D 169
                ||:.....::|....:..:...|:..|..|: :|..:|:...|...||.           |
Zfish    23 ----LLVGSTTLFFVFTCPWLTKAVSPVVPLYNGIVFLFVLANFSMATFMDPGVFPRADEDEDKD 83

  Fly   170 KELRR-VHRNDRIVPEFDRSKHSHVIENGRCHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNH 233
            .:.|. :::|..|.....|.|.        |..|:..... |..|||||:.||.:|||||.|:|:
Zfish    84 DDFRAPLYKNVEIKGIQVRMKW--------CATCHFYRPP-RCSHCSVCDNCVEEFDHHCPWVNN 139

  Fly   234 CIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITL 298
            |||.|||..|.:.::|.                                 |.|.:  |.|     
Zfish   140 CIGRRNYRYFFLFLLSL---------------------------------SVHMV--GVF----- 164

  Fly   299 SLSNGTMMLIEQHTSEEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQ 363
              |.|.:.::.        |.|         |:|.|.|.:   |.::..                
Zfish   165 --SFGLLFVLH--------HLE---------TLSALHTTV---TLVVMC---------------- 191

  Fly   364 PVVTGIGLNETIFMFLLGVLGLLAAVSAGLLLHLCFFHIYISFLGLTTYEYIRNH---------- 418
              |||        :|.:.|:||..            ||:.:...|.||.|.:...          
Zfish   192 --VTG--------LFFIPVMGLTG------------FHMVLVARGRTTNEQVTGKFRGGVNPFTR 234

  Fly   419 ----------------RQAQDAKTKQLLEGAPGVRAPKNGNVHFSASLPEP-------HNPSK-S 459
                            |...|.:.|..:...|....|...|.|.|..:.:.       .:.|| |
Zfish   235 GCGGNVKHVLCSPLAPRYIADPRKKIPVTVTPPFLRPDLSNRHISVKVSDNGIHSNILRSKSKTS 299

  Fly   460 LPGGQQLYCCSSAPHP------SQHSQESVGQTEQSLRLHCCASSR------------------- 499
            |.|.......:..|.|      :|...:.....|.||      ||:                   
Zfish   300 LNGMDDKSIDAQPPLPPKADRYNQIKSQLTSSEESSL------SSKPTNPSTPAMFKYRPSFGTM 358

  Fly   500 ---EFHQSGQAIYVC------SLLEEAVPQIQVEPDT--------------LSSFHCCSSFAASS 541
               .:|.:|:.|.:|      ::|||.....:.||:.              .||.....||:.:|
Zfish   359 PKVHYHATGEKIVMCENGNPSAVLEERSHDYRSEPNLDLPDYRSAPLHRTYQSSPFQLDSFSTTS 423

  Fly   542 LQRRVSLAKGSLISAEPRHLRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSSSTRTL 606
              |..||.:|.       :....|.|..|:..|:.:...|     |..|.|.:|....|.|..:|
Zfish   424 --RSFSLKQGV-------NRADCTPLGGTKHETITSTPHR-----GVFSPGTLSGRNSSLSYDSL 474

  Fly   607 TSQTGGSSASATAAGNISKHQRWRRKWNCCAAVP-------DSPDLPNDLLAALTFRESEEAAAA 664
                    .:.:.|.:|.:          |||.|       .||.||..:.          ....
Zfish   475 --------LTPSVAPSIGE----------CAAHPGVPSMGFHSPYLPTKMC----------HVRG 511

  Fly   665 AKLNAQELPIQFIRTLNGGL-DQELPL-KATTATPTPPRSSRLRYMLRLLGRYRRPRCRHGAHHG 727
            .:|.....|..:.....|.: .::.|| :.....|:|.|...|...:                  
Zfish   512 PELQRHAGPPSYSPVHIGAMYGRQSPLSRERERDPSPVRYDNLSKTI------------------ 558

  Fly   728 IAAKEHQNIGGSAIKQNQIRPLQLQAAGRGYANSTAT-----------PTPPASSPSRSSLESSD 781
            :|:.:.:       |:.:.|...:....:||||.:..           |..|....||.      
Zfish   559 MASIQER-------KEFEEREKLMHRHVQGYANDSGVFDTAYGLPHGYPDGPRGPASRE------ 610

  Fly   782 LSTSTSPSCGKKE-LMLLP--TSVIRDDSVTTYTLTLPPALPPPTRRKMNQTTQELAELAETLGF 843
               .|.|.|..:: ||..|  |.|:|..                                     
Zfish   611 ---PTPPVCASRDNLMGYPPRTPVLRSS------------------------------------- 635

  Fly   844 ASNLQHSQHNSQTNSRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLRHHHQNL 908
            ||:|..:...|.|:..|  ..|.:.|....::        .||:|:|..|..:.|:...:.||.:
Zfish   636 ASSLVRAPRTSTTSLHT--DGGGMNRTAELQY--------RSPVHQSHQSPTSVPRSPSYAHQKV 690

  Fly   909 A 909
            |
Zfish   691 A 691

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17075NP_608508.1 DHHC 199..>282 CDD:396215 25/82 (30%)
zdhhc8bNP_840089.3 DHHC 99..224 CDD:396215 53/233 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 293..346 13/58 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 437..461 7/28 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 633..659 8/64 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 666..685 6/18 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 703..736
Blue background indicates that the domain is not in the aligned region.

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