DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17075 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	257	Identity:	55/257 - (21%)
Similarity:	91/257 - (35%)	Gaps:	96/257 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 RKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWV----LIPAFHARIQGPLYGLIT-GLYLVHIA 157
            ||.:.|..|.|.|..|   |::         |:|    ::|  ..|:......|:| ||.|:.:|
Mouse   128 RKEQTLFFLSLGLFSL---GYM---------YYVFLREVVP--QGRVGPTQLALLTCGLLLILLA 178

  Fly   158 SHLTALLTDPADKELRRVHRNDRIVPEFDRSKHSHVIE----------------------NGRCH 200
                          |.|..:|...:.. |:|..:..||                      |.|..
Mouse   179 --------------LYRAKKNPGYLSN-DKSPSNSQIECPVKKGQEKTKGFPGTDASGSLNNRTL 228

  Fly   201 LCNIRTSSN-----------------------RTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVA 242
            ..::|.||.                       |..||.:|..||.:.||||.|:|.|:|..|:.|
Mouse   229 KDDVRGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQA 293

  Fly   243 FLMCVVSAVVATLVIVAAVVAQIVFYYIQPD---WLSFYWCPTESSHTIESGDFINITLSLS 301
            |::     .::..::.:.....:....|..|   :.:.::||         |.:.|.:.:||
Mouse   294 FIL-----ALSIFLLTSVYGISLTLNTICRDRSLFTALFYCP---------GVYANYSSALS 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	23/108 (21%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	25/108 (23%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900