DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17075 and si:ch211-223a10.1

DIOPT Version :9

Sequence 1:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	XP_009305694.1	Gene:	si:ch211-223a10.1 / 101884554	ZFINID:	ZDB-GENE-090313-86	Length:	544	Species:	Danio rerio

Alignment Length:	386	Identity:	81/386 - (20%)
Similarity:	130/386 - (33%)	Gaps:	150/386 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ISTAGLTES---HSESPAKGVVTPVRKPHSLGSED-----------SPENI---------IPGEQ 69
            |:|..|.|:   |...|....|||:....|.|:.|           |||.:         :..|:
Zfish   119 IATQYLWETRMFHFSDPDNYQVTPLHLAASTGNTDVVRYLLRANRCSPEAVDHQGATALHVAAEK 183

  Fly    70 A---------------------ETNKKPLHLCRLSQLVSYQ--SNIADVQHRKGRRLHGLQLPLH 111
            .                     .|...||.||.......:|  |.|.....::.:.|    :|..
Zfish   184 GMIEVCWLLLKSAGLHILHMTNHTGLTPLDLCNQGNTFRHQQLSKILTDFSQQPKNL----IPKD 244

  Fly   112 PLQIFGWLVLL--LFGVA---------SYW-----VLIP--------AFH-----ARIQGP---- 143
            ...::.|::||  |.|||         .|.     ||.|        .:|     .|:..|
Zfish   245 SYVMYFWMLLLPSLSGVAVLVIAAALGEYGGIFSAVLFPFMAKTILSQYHRLSSFQRLPNPVYLG 309

  Fly   144 -------------LYGLITGLYLVHIASHLT-------------ALLTDPADKELRRVHRNDRIV 182
                         ||.:|...:..|...||:             .|...|.  :|:....:.|.
Zfish   310 TLTAGLIHSTVCFLYKIIPSFWPAHTLLHLSLVHFCVLAGLFWKVLKQSPG--QLKDADTDSRF- 371

  Fly   183 PEFDRSKHSHVIENGR-----CHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVA 242
                 |....::|.|:     |..|.:....| .|||.:|:.|:..:||||.::|.|:|..|:..
Zfish   372 -----SSIGDLMEAGQSPDRFCIYCELIQVEN-CKHCRLCDMCIKDYDHHCLFINQCVGRENHRT 430

  Fly   243 FLMCVVSAVVATLVIVAAVVAQIVFYYIQ------PDW------------------LSFYW 279
            |::.::|.|:|.|:.   :::.|.:.|::      .||                  ||.:|
Zfish   431 FILFLMSMVMAHLIF---ILSAIFYLYLKVSGLQLSDWGSVAGREAWVLLLTLLNLLSLFW 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	28/105 (27%)
si:ch211-223a10.1	XP_009305694.1	ANK repeat	7..36	CDD:293786
		Ank_2	9..102	CDD:289560
		ANK	39..159	CDD:238125	12/39 (31%)
		ANK repeat	39..69	CDD:293786
		ANK repeat	71..102	CDD:293786
		Ank_2	76..162	CDD:289560	12/42 (29%)
		ANK repeat	138..170	CDD:293786	9/31 (29%)
		Ank_4	139..192	CDD:290365	10/52 (19%)
		zf-DHHC	384..509	CDD:279823	28/109 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810