DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17075 and zdhhc17

DIOPT Version :9

Sequence 1:	NP_001245821.1	Gene:	CG17075 / 33191	FlyBaseID:	FBgn0031239	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_001121854.1	Gene:	zdhhc17 / 100148543	ZFINID:	ZDB-GENE-070424-194	Length:	620	Species:	Danio rerio

Alignment Length:	243	Identity:	61/243 - (25%)
Similarity:	91/243 - (37%)	Gaps:	101/243 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LQIFGWLVLLLFGV--ASYWVLIP---------AFHARIQGPLY------GLITGLY-----LVH 155
            |.|..||:.   ||  |..|:::.         :.|:.:...:|      ..||..|     |..
Zfish   311 LDIDSWLIK---GVMYAVMWLVVQFLSKSFFDHSMHSALPLGIYLATKFWMYITWFYWFWNDLPF 372

  Fly   156 IASHLTALL--------------TDPADKELRRVHRNDRIVPEFDRSKHSHVIENGR-------- 198
            :..||..||              :||.            |:...:..|...::|...
Zfish   373 VTIHLPFLLNSLALFYNFGKSWKSDPG------------IIKASEEQKKKTIVELAETGSLDLSI 425

  Fly   199 -CHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRN------YVAFLMCVVSAVVATLV 256
             |..|.|| ...|:|||:|||:|:.||||||.|:.:|:||.|      |:.||:|::.
Zfish   426 FCSTCLIR-KPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRYFMGYLFFLLCMIC------- 482

  Fly   257 IVAAVVAQIVFYYIQPDWLSF----YW---CPTESSHTIESGDFINIT 297
                             |:.:    ||   |.|  |:| :.|.:|.||
Zfish   483 -----------------WMMYGCICYWRIHCAT--SYT-KDGFWIYIT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17075	NP_001245821.1	zf-DHHC	199..>282	CDD:279823	31/95 (33%)
zdhhc17	NP_001121854.1	PHA02874	<59..>253	CDD:165205
		ANK repeat	77..108	CDD:293786
		ANK 1. /evidence=ECO:0000255	77..106
		ANK repeat	110..142	CDD:293786
		ANK 2. /evidence=ECO:0000255	111..140
		ANK repeat	144..175	CDD:293786
		ANK 3. /evidence=ECO:0000255	144..173
		Ank_2	150..243	CDD:403870
		ANK repeat	177..209	CDD:293786
		ANK 4. /evidence=ECO:0000255	177..207
		ANK repeat	212..243	CDD:293786
		ANK 5. /evidence=ECO:0000255	212..241
		ANK 6. /evidence=ECO:0000255	245..274
		DHHC	426..556	CDD:396215	38/113 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900