Protein Alignment Dus1 and DUS4L

DIOPT Version :10

• Sequence 1: NP_608507.1
• Gene: Dus1 / 33190
• FlyBaseID: FBgn0031238
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_853559.1
• Gene: DUS4L / 11062
• HGNCID: 21517
• Length: 317
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 106/302 - (35%)
• Similarity: 159/302 - (52%)
• Gaps: 25/302 - (8%)

  Fly    31 VVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQ 95
            |.||||..|:||:|.|.|:|..:|||:||..|..|....|.|.....|...|.|||:||..|||:
Human    30 VCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDAR 94

  Fly    96 QILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLAVP---VTCKI 157
            .:.|||.:...:.:.:|||.||||..|....||:.|.::.||:.::|..:..::..|   |:.||
Human    95 LLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKI 159

  Fly   158 RIFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQK-GPLTGVANWNYIKNVRQHIKIPMLANGNIL 221
            ||.:||::|:...:..||.|...:||||||.|:: .|:    :::.||.:::::.||::|||:|.
Human   160 RIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPV----HYDSIKIIKENMSIPVIANGDIR 220

  Fly   222 ALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPP----VWQMAHEYLELVQLHPCPSSFIRGH 282
            :|.:.......||.||||.|.|.|.|||:|.|....    :|......|||            |.
Human   221 SLKEAENVWRITGTDGVMVARGLLANPAMFAGYEETPLKCIWDWVDIALEL------------GT 273

  Fly   283 LFKLFH-HIMNIRQNSELRQYLATANQLVQFQAVVQQVRAKY 323
            .:..|| |:|.:.:....||.....|.|....|::..:...|
Human   274 PYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIIDYLTDHY 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dus1	NP_608507.1	DUS_like_FMN	29..259	CDD:239200	91/235 (39%)
DUS4L	NP_853559.1	DUS_like_FMN	28..257	CDD:239200	91/230 (40%)