DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13693 and ccdc96

DIOPT Version :9

Sequence 1:	NP_608505.1	Gene:	CG13693 / 33187	FlyBaseID:	FBgn0031235	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001122170.1	Gene:	ccdc96 / 559167	ZFINID:	ZDB-GENE-081022-156	Length:	479	Species:	Danio rerio

Alignment Length:	512	Identity:	104/512 - (20%)
Similarity:	199/512 - (38%)	Gaps:	129/512 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LKTDT--QSRRSVKSHPSKLHVFEY-----AAPQDLDVVAIIYKFYLEDFRNFTEEERQLRLSSL 66
            |:|||  ::.::::.......|.|.     .||.:.:.|               ||::..:|.:.
Zfish    16 LETDTLMENTKTLEGPADAEQVMEEETEEPEAPNNPEAV---------------EEDKAEQLLTE 65

  Fly    67 DAIDMLHTIEQVHNDVATLRLENHIMVEFLEKNDPKLLLGLRQRRTSILRKLQTKRG-----SAQ 126
            |. .:..|.||   ....:::|.|::.|    .||.:           ...|:...|     |.:
Zfish    66 DT-SVPETSEQ---QTGEIQIEQHLITE----EDPLM-----------NETLEDTEGPETEPSLE 111

  Fly   127 GSHGVNSRHSSSKRSIPMSVNQLVSISGISAPEKRRG--MDYKLN---FKAKAEMAEKRAAEVEK 186
            .|..........:.|:|....:  :...||.||:.:.  .|.:::   .|.|.|:..|..:|.||
Zfish   112 DSEDEEEEEEDEENSLPAPEPE--NERSISPPEEPQAHTEDEEVDPSIIKEKMELLHKLQSENEK 174

  Fly   187 RVADIERNAMTEV-KQLRAKIEELRFRSEETIETENNF-------------MLHF--LRDE--ND 233
             :..|.:...|.: :....|..:...:.:|.|..:..:             .|||  |..|  .|
Zfish   175 -LNKINQQLQTRIAEHFSKKKGDQHVKLDEDISEQEQYEKYMQLIADMKEQQLHFSKLHQERMED 238

  Fly   234 VAFLESATERQIERKLRKFTSNWFKNA--RALLG--------------------------TMKLT 270
            :....|...:|:|::||.|.:..::..  .:|.|                          .::|.
Zfish   239 LHLQSSEKLKQVEQELRFFAALKYETVMKASLTGKVGKQETLAKVELLKAEELKQEDKLVCVRLN 303

  Fly   271 IVSLQETCQQHRADLITKSDLSGILTAVDFEKLIIKRTELVNQLEEKN--IHMAGLKGVTGKTSL 333
            .:.|:....::...|.:|.:|...|..:|||:|..:....:::|||::  :|....|..:....:
Zfish   304 NIKLKNKISKYERALRSKRELVDGLLLMDFEQLKTENQSFMDKLEERSEELHRLKKKVASSVQGI 368

  Fly   334 AMTEEKQAMMNLETEMR-TVLNRTDEVTRAIQKLEKEVAAVQMHNTKDYVTLDELRAQ------- 390
            :..:||...|.:|.:.: |.|.:||    .:..|::|| ..:....:|.:..|.|:.|
Zfish   369 SHVKEKLHFMQMENKAKHTQLAQTD----TLVALKREV-LTRTRQVRDGLRTDNLKLQQRSGLMG 428

  Fly   391 ----LQDYEAPSVSEYIERKEEAHVLEKEEKMLQRKIYILNMKLNNAIR--RRNRLE 441
                |||||        |:.:.:..|:::.:||::....|:||.....|  :.:|||
Zfish   429 NTTLLQDYE--------EKMDTSENLQQKLEMLKKHHAELSMKCAGVQRKIKDSRLE 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13693	NP_608505.1	DUF4201	258..432	CDD:290581	44/215 (20%)
ccdc96	NP_001122170.1	DUF4201	290..466	CDD:290581	42/188 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28MPJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.860