Protein Alignment kis and MOM

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_001322007.1
• Gene: MOM / 837322
• AraportID: AT1G08060
• Length: 2002
• Species: Arabidopsis thaliana
• Alignment Length: 2502
• Identity: 460/2502 - (18%)
• Similarity: 782/2502 - (31%)
• Gaps: 865/2502 - (34%)

  Fly  1503 RTPPPSPPPDSEMDS-NKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASN-- 1564
            |:...|.|...|.:: ..|||||.|...|.|....   :..::..|..||....||......|
plant    17 RSLAASIPASVEQETPGLRRSSRGTPSTKVITPAS---ATRKSERLAPSPASVSKKSGGIVKNST 78

  Fly  1565 ------SNAGSDVEKTEPQSGAE-----GDAAQEVGEEKSNLPLDESSQ-----LEASSSTSAVA 1613
                  ||.|......:...|::     ||.:.::.:.|.:  ::||:.     :.|.|..:...
plant    79 PSSLRRSNRGKTEVSLQSSKGSDNSIRKGDTSPDIEQRKDS--VEESTDKIKPIMSARSYRALFR 141

  Fly  1614 EKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQ-DEE 1677
            .|.::     :.|.:.:.||       :|:.:||.....:..|..::   :.|...|.|.. ..:
plant   142 GKLKE-----SEALVDASPN-------EEELVVVGCSRRIPAGNDDV---QGKTDCPPPADAGSK 191

  Fly  1678 KSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKD 1742
            :..:||.:.||  |.: |..     |.:|::|:..|::|.:     .|:..|....|..:|.:..
plant   192 RLPVDETSLDK--GTD-FPL-----KSVTETEKIVLDASPI-----VETGDDSVIGSPSENLETQ 243

  Fly  1743 KMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKAND 1807
            |:    :.||:|.......:|:|:...|.|                       ||| |..:|..|
plant   244 KL----QDGKTDCSPPANAESKTLPVGETS-----------------------LEK-EYPQKFQD 280

  Fly  1808 DQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKP 1872
            |             :||...|..|             |.:|:..||.|::|:.|...::..|...
plant   281 D-------------NTDCLPPANA-------------ESKRLPVGETSLEKDTDFPLKSTTETGK 319

  Fly  1873 EPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQ 1937
            ..::...   .|:.|:.|.: |...|..|                   :|:|.:         ::
plant   320 MVLYASP---IVETRDDSVI-CSPSTNLE-------------------TQKLLV---------SK 352

  Fly  1938 DFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEED----VDNDKIEQYLRFNKIP 1998
            ...|.|.||.:....|                      |.|:|.|    |.|...........||
plant   353 TGLETDIVLPLKRKRD----------------------TAEIELDACATVANGDDHVMSSDGVIP 395

  Fly  1999 QRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQ 2063
            ..|..|:..|  ||:....:|.....|....|               :..:||
plant   396 SPSGCKNDNR--PEMCNTCKKRQKVNGDCQNR---------------SVCSCI------------ 431

  Fly  2064 SLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTES 2128
                               :.|:....|..:      ||...   |.|||:    :||...:.:.
plant   432 -------------------VQPVEESDNVTQ------DMKET---GPVTSR----EYEENGQIQH 464

  Fly  2129 GKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLL 2193
            ||
plant   465 GK--------------------------------------------------------------- 466

  Fly  2194 SGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKS 2258
                                    ||..:|.|                                |
plant   467 ------------------------SSDPKFYS--------------------------------S 475

  Fly  2259 LAPKEETIIEVELTNIQ-KKYYRGILEQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNGA 2322
            :.|  |..:.|:|:::| ::|.:.:..::.|.  ...:..::..|..|:..:||.|.|||:::.:
plant   476 VYP--EYWVPVQLSDVQLEQYCQTLFSKSLSL--SSLSKIDLGALEETLNSVRKTCDHPYVMDAS 536

  Fly  2323 EEQIQYDFKSQHGEDPESYYKNL---------ILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRC 2378
            .:|:              ..|||         |.::||:.|:||:|..:|.||.:.::|.|....
plant   537 LKQL--------------LTKNLELHEILDVEIKASGKLHLLDKMLTHIKKNGLKAVVFYQQATQ 587

  Fly  2379 L-------DILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLT 2436
            .       :||||::..|..| :..:..|..:.:..||:.::|. |...|.||.|:|....|.|.
plant   588 TPEGLLLGNILEDFVGQRFGP-KSYEHGIYSSKKNSAINNFNKE-SQCCVLLLETRACSQTIKLL 650

  Fly  2437 AADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQS 2501
            .||..|::.|..||.:|::...:.......:..||:||....|.|             :||::.:
plant   651 RADAFILFGSSLNPSHDVKHVEKIKIESCSERTKIFRLYSVCTVE-------------EKALILA 702

  Fly  2502 MNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVM----------------DDDNAGDKFCEEDIDSI 2550
            ..       |.:|  .|.:|:|.:...:..:|                :..::|..|.:..:|.:
plant   703 RQ-------NKRQ--NKAVENLNRSLTHALLMWGASYLFDKLDHFHSSETPDSGVSFEQSIMDGV 758

  Fly  2551 LKRRTQVITMESEKGS--------TFSKASFAASGNRSDITIDDPD------------FWTK--- 2592
            :...:.::   |.||.        ...:|..|.....||.|:...|            ||:|
plant   759 IHEFSSIL---SSKGGEENEVKLCLLLEAKHAQGTYSSDSTLFGEDHIKLSDEESPNIFWSKLLG 820

  Fly  2593 -----WAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYGHEDVMELNSEESSNENSDEEGGIGL 2652
                 |....|                 .|:|..:..:|       ....|:|.:..|  ||
plant   821 GKNPMWKYPSD-----------------TPQRNRKRVQY-------FEGSEASPKTGD--GG--- 856

  Fly  2653 RSRRRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSEL 2717
            .:::||        |..:|...||..|
plant   857 NAKKRK--------KASDDVTDPRVTD-------------------------------------- 875

  Fly  2718 LELGQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNL 2782
                                                        .|.:|.|.:...:||.|.
plant   876 --------------------------------------------PPVDDDERKASGKDHMGA--- 893

  Fly  2783 VPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDK---DSGGINASAVAAAVT 2844
                       .||..|.|......|....|         .|||:|.   .|.|.:.|.:...:.
plant   894 -----------LESPKVITLQSSCKSSGTDG---------TLDGNDAFGLYSMGSHISGIPEDML 938

  Fly  2845 SIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISE 2909
            :..|   |.|... ::...|....|..:.:     |.:|..|......::|:|::.:.:|..|.|
plant   939 ASQD---WGKIPD-ESQRRLHTVLKPKMAK-----LCQVLHLSDACTSMVGNFLEYVIENHRIYE 994

  Fly  2910 LPIRPPPT--PDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLA 2972
               .|..|  ..|:..||...:...:.|     .|...:.|                  |..:||
plant   995 ---EPATTFQAFQIALSWIAALLVKQIL-----SHKESLVR------------------ANSELA 1033

  Fly  2973 VTSLPINEDDANS----------KHDDGDEVDDDGTTTTKDSDSTK-----LTGGDNKDSLLDPE 3022
            .....:..|...|          :|..|.:.|..||.:.:...|||     |:|...:|..::
plant  1034 FKCSRVEVDYIYSILSCMKSLFLEHTQGLQFDCFGTNSKQSVVSTKLVNESLSGATVRDEKIN-- 1096

  Fly  3023 RPSSSGKSSSENASGGNDK------TESENDATTVS--ESSYKSEVLPGKGSDLDVSVAQQDALS 3079
              :.|.::|||:.....:|      |.:.:...|:|  :..||.:          |....|:...
plant  1097 --TKSMRNSSEDEECMTEKRCSHYSTATRDIEKTISGIKKKYKKQ----------VQKLVQEHEE 1149

  Fly  3080 ATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAG---KAQGTGVQTGDAGELD-------- 3133
            ...||.|....|..|.:.            |.|.|||.   ....|..|.||...||
plant  1150 KKMELLNMYADKKQKLET------------SKSVEAAVIRITCSRTSTQVGDLKLLDHNYERKFD 1202

  Fly  3134 -IESEKKDNEKETKESTGDAPAVEAKKDSAAIARAE--GDKTESCT-----NN----ATTNISTT 3186
             |:|||.:..|..::....|....|:.::..|.|.:  ..|.:.|.     ||    .::|||..
plant  1203 EIKSEKNECLKSLEQMHDVAKKKLAEDEACWINRIKSWAAKLKVCVPIQSGNNKHFSGSSNISQN 1267

  Fly  3187 TTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSM 3251
            .....|.|..    |..:..|::|......|.     :.|.|:..|    |::.  .:|.....|
plant  1268 APDVQICNNA----NVEATYADTNCMASKVNQ-----VPEAENTLG----TMSG--GSTQQVHEM 1317

  Fly  3252 QDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGS 3316
            .|:.......::|..|    |:|...|..:..::  :.|.:.:|.....:...:.:.........
plant  1318 VDVRNDETMDVSALSR----EQLTKSQSNEHASI--TVPEILIPADCQEEFAALNVHLSEDQNCD 1376

  Fly  3317 GIGSSA-QHDASGR------SLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAM 3374
            .|.|:| ..|.|.|      ||:.|..|...|.:...|...:..    ..:..||.
plant  1377 RITSAASDEDVSSRVPEVSQSLENLSASPEFSLNREEALVTTEN----RRTSHVGF--------- 1428

  Fly  3375 PTAADISLMLSILNTTDVNQLANLD---INKLAMYLVSMNNKMERQGKME--------------L 3422
                |...:|...|..|    .:||   .::|||.:..:.:.:|.:|..|              |
plant  1429 ----DTDNILDQQNRED----CSLDQEIPDELAMPVQHLASVVETRGAAESDQYGQDICPMPSSL 1485

  Fly  3423 AAKE------RESQRL-QLIPKKWNRREEYEFLRVLTGYGVDLHVSTPMASS-NGSSLSPDWTKF 3479
            |.|:      .||:.| :.|..:....|..|.......:..| .|:.|:.|| .|:..:|:
plant  1486 AGKQPDPAANTESENLEEAIEPQSAGSETVETTDFAASHQGD-QVTCPLLSSPTGNQPAPE---- 1545

  Fly  3480 KQMAHLERKSDETLT-------------DYYKVFVAMCKRQAGLKLSESERGLEGII-EEIEKEH 3530
               |::|.::..|..             ||..:.......|....|.....|.:..: ..||.::
plant  1546 ---ANIEGQNINTSAEPHVAGPDAVESGDYAVIDQETMGAQDACSLPSGSVGTQSDLGANIEGQN 1607

  Fly  3531 ----AKLILDRLEVLAKLREVARNPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKHGLYRS 3591
                |:|..|..:.:.    ...:|:.::    |.::|.......||.|..   |||...||..:
plant  1608 VTTVAQLPTDGSDAVV----TGGSPVSDQ----CAQDASPMPLSSPGNHPD---TAVNIEGLDNT 1661

  Fly  3592 ETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAE 3656
            ..   .:|:.|..::.:..|.|...|::|:.....|:....|..|.......:.....||:.|.:
plant  1662 SV---AEPHISGSDACEMEISEPGPQVERSTFANLFHEGGVEHSAGVTALVPSLLNNGTEQIAVQ 1723

  Fly  3657 KAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEESTKIK 3721
            ....:...|  .:|..:.....:::||      |..|.....:|......||.|.::.:...:.|
plant  1724 PVPQIPFPV--FNDPFLHELEKLRRES------ENSKKTFEEKKSILKAELERKMAEVQAEFRRK 1780

  Fly  3722 GKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKC 3786
            ..|      .|.|....:|.:.|||:                       |.:...........||
plant  1781 FHE------VEAEHNTRTTKIEKDKN-----------------------LVIMNKLLANAFLSKC 1816

  Fly  3787 SDAEDKKFSEEKPSSPAVPDGKVSEMEADEAA 3818
            :|        :|.|....|.||:.:: |..||
plant  1817 TD--------KKVSPSGAPRGKIQQL-AQRAA 1839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	88/439 (20%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	12/66 (18%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	11/61 (18%)
		PLN03142	2029..>2606	CDD:215601	107/637 (17%)
		PTZ00341	<3662..3887	CDD:173534	30/157 (19%)
		BRK	4568..4611	CDD:462196
MOM	NP_001322007.1	PLN03142	<523..>851	CDD:215601	83/392 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	553..667	CDD:476819	36/115 (31%)
		PRK04654	1741..1964	CDD:135173	28/143 (20%)
		PHA03247	<1859..1963	CDD:223021