Protein Alignment kis and CHR24

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_201200.2
• Gene: CHR24 / 836516
• AraportID: AT5G63950
• Length: 1090
• Species: Arabidopsis thaliana
• Alignment Length: 1241
• Identity: 300/1241 - (24%)
• Similarity: 497/1241 - (40%)
• Gaps: 368/1241 - (29%)

  Fly  1641 DEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDL 1705
            ||::....:.||   |:|.|....|||              |||             :|....||
plant    41 DEETKKSMIKLA---GRRRLCKALPKE--------------DEA-------------DGYDDPDL 75

  Fly  1706 TD-----SEETKLESSAM--EVDSKEESEPDDSKKSDEDN--------------KDKDKME---- 1745
            .|     ..||.|:|:.:  :..|.:||:..:::.:.|.|              |.|::|:
plant    76 VDFYSPVKGETSLDSAGIGNKFTSWDESKEANTELAGEPNFSIITDFCSPSPQLKQKEEMQGDGG 140

  Fly  1746 -------VDD---EVGKSDKESKPEEQSET-----VKTEENSKAIEEDKSSTVLTADHAKEPETV 1795
                   :||   ::|....:.|.:.||..     ||::.:....|:.|||..|.:|.:|
plant   141 RNEIMGILDDLTSKLGTMSIQKKKDSQSNDFDACGVKSQVDKFDFEDAKSSFSLLSDLSK----- 200

  Fly  1796 LEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKEN 1860
                                          |:|:..||               ...|..|:|.:.
plant   201 ------------------------------SSPDVVTT---------------YNAGVNSIKDKQ 220

  Fly  1861 DEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLN 1925
            .:...|..|.:..             :.||.   ||  ||.:....::.:...|.|.
plant   221 GKSGFAIREEQTS-------------KEFSR---EW--EERISNVGKQNSYSGRHFD-------- 259

  Fly  1926 IFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLV--KWKSLPYEDCT--WELEEDVDND 1986
              :|.||   |:....:||........|: |.:||:|..|  |.:::...:..  .:|:||.|:|
plant   260 --DNSED---NRQGYNLDRGKSQCKEVDQ-SMKTTRHIEVSEKIRTVGRSNAAKLRDLDEDDDDD 318

  Fly  1987 -------KIEQYLRFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGN-----------SLRPYQ 2033
                   |....::.|| |.|| :.:|:..:.|...:.|.:....|.|           .|.|:|
plant   319 DCLILSGKKAAEMKINK-PARS-YNAKRHGYDERSLEDEGSITLTGLNLSYTLPGKIATMLYPHQ 381

  Fly  2034 LEGLNWLKFSWYNTH----NCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQR 2094
            .||||||    ::.|    ..||.|:||||||:|..:|:..::...:....||:||.:.:|:|.:
plant   382 REGLNWL----WSLHTQGKGGILGDDMGLGKTMQICSFLAGLFHSKLIKRALVVAPKTLLPHWMK 442

  Fly  2095 EFE--GWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMI--------- 2148
            |..  |.:.| ...|:|:.|.   .::|:.::..: ||        .:|:||::::
plant   443 ELATVGLSQM-TREYYGTSTK---AREYDLHHILQ-GK--------GILLTTYDIVRNNTKALQG 494

  Fly  2149 ---VTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLN 2210
               .||..|.....|...::||.|.:||.|.:..:.|.::...||:::||||:|||:.||::|.|
plant   495 DDHYTDEDDEDGNKWDYMILDEGHLIKNPNTQRAKSLLEIPSSHRIIISGTPIQNNLKELWALFN 559

  Fly  2211 FLEPSQFSSQEEFMSEFGS--LR------TEEE-------VNKLQALLKPMMLRRLKDDV----- 2255
            |..|.....:..|...:..  ||      |:.|       ...|:..::|..|||||.:|
plant   560 FSCPGLLGDKNWFKQNYEHYILRGTDKNATDREQRIGSTVAKNLREHIQPFFLRRLKSEVFGDDG 624

  Fly  2256 -EKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLL 2319
             ...|:.|:|.::.:.||..|::.|...|....      ..||...:.:..:..|:|.|.||.||
plant   625 ATSKLSKKDEIVVWLRLTACQRQLYEAFLNSEI------VLSAFDGSPLAALTILKKICDHPLLL 683

  Fly  2320 N--------------------GAEEQIQY---------DFKSQHGEDPESYYKNLILSAGKMVLI 2355
            .                    |..|::..         ||::::  |..|...:.|:|     |:
plant   684 TKRAAEDVLEGMDSTLTQEEAGVAERLAMHIADNVDTDDFQTKN--DSISCKLSFIMS-----LL 741

  Fly  2356 DKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRF 2420
            :.|:|:    |||||||||..:.|::::|.|....|.|.||||..:...|.:.::.:.: |....
plant   742 ENLIPE----GHRVLIFSQTRKMLNLIQDSLTSNGYSFLRIDGTTKAPDRLKTVEEFQE-GHVAP 801

  Fly  2421 VFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMF 2485
            :|||.::.||||:.||.||.||:.|..|||..|.|:..|.:||||.|.|.:|||:...|.|.:::
plant   802 IFLLTSQVGGLGLTLTKADRVIVVDPAWNPSTDNQSVDRAYRIGQTKDVIVYRLMTSATVEEKIY 866

  Fly  2486 DKASMKLGLDKAVLQSMNTQGSKDGNNKQL---SKKEIEDL--LKKGA--------------YGA 2531
            .|...|.||.|...:          :.:|:   |::::.:|  |.||.              |..
plant   867 RKQVYKGGLFKTATE----------HKEQIRYFSQQDLRELFSLPKGGFDVSPTQQQLYEEHYNQ 921

  Fly  2532 VMDDDNAGD--KFCEE------DIDSILKRRT---QVITMESEK------GSTFSKASFAASGNR 2579
            :..|:....  ||.|.      ...|:|..:|   |.|..:.|:      .....:||.:.|
plant   922 IKLDEKLESHVKFLETLGIAGVSHHSLLFSKTAPIQAIQKDEEEQIRRETALLLGRASASIS--- 983

  Fly  2580 SDITIDDPDFWTK-----WAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYGHEDVMELNSEES 2639
            .|..|:..|:..|     ..|:::|.|       .:|..|||...:.::.|.    .|.|.::.:
plant   984 QDTVINGADYAFKPKDVNLDKRINISP-------VDDKELSESVIKARLNRL----TMLLQNKGT 1037

  Fly  2640 SNENSDEEGGIGLRSR----RRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECF 2700
            .:...|  ||..::.:    .|:.|..:|.|:....:.|..|.|...
plant  1038 VSRLPD--GGAKIQKQIAELTRELKDMKAAERINMPQVIDLEEDISR------------------ 1082

  Fly  2701 KVEKGL 2706
            |::|||
plant  1083 KMQKGL 1088

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	61/321 (19%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	13/66 (20%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	15/68 (22%)
		PLN03142	2029..>2606	CDD:215601	189/685 (28%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
CHR24	NP_201200.2	PLN03142	323..>872	CDD:215601	169/585 (29%)
		DEXHc_ERCC6L	377..614	CDD:350759	73/253 (29%)