Protein Alignment kis and RAD5

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_197667.1
• Gene: RAD5 / 832338
• AraportID: AT5G22750
• Length: 1029
• Species: Arabidopsis thaliana
• Alignment Length: 1124
• Identity: 236/1124 - (20%)
• Similarity: 393/1124 - (34%)
• Gaps: 386/1124 - (34%)

  Fly  1619 ISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRE------LILDKPKEKAPEPKQDEE 1677
            :.|..::..:|:..:.|..:..|.|     ::.|:.|...:      :|.|.|....|
plant     1 MGTKVSDDLVSTVRSVVGSDYSDMD-----IIRALHMANHDPTAAINIIFDTPSFAKP------- 53

  Fly  1678 KSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKD 1742
                 :..|..|.|....|......|..|..     :|.::..:.:.|.|.:......|::...:
plant    54 -----DVATPTPSGSNGGKRVDSGLKGCTFG-----DSGSVGANHRVEEENESVNGGGEESVSGN 108

  Fly  1743 KMEVDDEVGKSD-------KESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKME 1800
            :...   ||.|:       |..|.:...|.|.|..:||.:               :|||...|..
plant   109 EWWF---VGCSELAGLSTCKGRKLKSGDELVFTFPHSKGL---------------KPETTPGKRG 155

  Fly  1801 VDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKE----------GEES 1855
            ...    .:.|:..|......||.||                 ||..|:..          .::.
plant   156 FGR----GRPALRGASDIVRFSTKDS-----------------GEIGRIPNEWARCLLPLVRDKK 199

  Fly  1856 VKKENDEKTEADMENKPEPVFIDVEEY-----FVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRR 1915
            ::.|...|:..:..:..:.:.:.|..|     |.|:...|:.......||.:.
plant   200 IRIEGSCKSAPEALSIMDTILLSVSVYINSSMFQKHSATSFKTASNTAEESMF------------ 252

  Fly  1916 FQQKQSQQLNIFENIEDEPFN------QDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYED 1974
                 ....|:|..:...||.      :||....|.|...   |.::..|:...|.|.|:
plant   253 -----HPLPNLFRLLGLIPFKKAEFTPEDFYSKKRPLSSK---DGSAIPTSLLQLNKVKN----- 304

  Fly  1975 CTWELEEDVDNDKIEQYL------RFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQ 2033
                :.:|.:.|:.||.:      ....:...|..|..:.||..|.:             |||||
plant   305 ----MNQDANGDENEQCISDGDLDNIVGVGDSSGLKEMETPHTLLCE-------------LRPYQ 352

  Fly  2034 LEGLNWLKFSWYNTHNC------------------------------------------------ 2050
            .:.|:|:  :.....||
plant   353 KQALHWM--TQLEKGNCTDEAATMLHPCWEAYCLADKRELVVYLNSFTGDATIHFPSTLQMARGG 415

  Fly  2051 ILADEMGLGKTIQ--SLTFVHS-----------VYE----------------------YGI---- 2076
            ||||.||||||:.  ||...||           .||                      .|.
plant   416 ILADAMGLGKTVMTISLLLAHSWKAASTGFLCPNYEGDKVISSSVDDLTSPPVKATKFLGFDKRL 480

  Fly  2077 --------RGPFLVIAPLSTIPNWQREFEGWT---DMNVVVYHGSVTSKQMIQDYEYYYKTESGK 2130
                    .|..|::.|::.:..|:.|.|...   .::|.|::|....|             ..|
plant   481 LEQKSVLQNGGNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYGQSRPK-------------DAK 532

  Fly  2131 VLKEPIKFNVLITTFEMIVT--------DYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNL 2187
            :|.:.   :|:|||:.::.:        |:..:.|..|...|:||||.:||...::......|..
plant   533 LLSQS---DVVITTYGVLTSEFSQENSADHEGIYAVRWFRIVLDEAHTIKNSKSQISLAAAALVA 594

  Fly  2188 EHRVLLSGTPLQNNISELFSLLNFLEPSQFSS--------QEEFMSEFGSLRTEEEVNKLQALLK 2244
            :.|..|:|||:|||:.:|:|||.||....:.:        |:.|  |.|.   |..:..:|::||
plant   595 DRRWCLTGTPIQNNLEDLYSLLRFLRIEPWGTWAWWNKLVQKPF--EEGD---ERGLKLVQSILK 654

  Fly  2245 PMMLRRLKDDVEKS------LAPKEETIIEVELTNIQKKYYRGILEQN----FSFLKKGTTSANI 2299
            |:||||.|...::.      |.|.:..:|..||:..::.:|..:.:::    ..|:::|....|.
plant   655 PIMLRRTKSSTDREGRPILVLPPADARVIYCELSESERDFYDALFKRSKVKFDQFVEQGKVLHNY 719

  Fly  2300 PNLMNTMMELRKCCIHPYL--------------------LNG-----------------AEEQIQ 2327
            .:::..::.||:||.||:|                    |:|                 .:|.::
plant   720 ASILELLLRLRQCCDHPFLVMSRGDTAEYSDLNKLSKRFLSGKSSGLEREGKDVPSEAFVQEVVE 784

  Fly  2328 YDFKSQHGEDP----------------------------------------------------ES 2340
            ...|.:.||.|                                                    ||
plant   785 ELRKGEQGECPICLEALEDAVLTPCAHRLCRECLLASWRNSTSGLCPVCRNTVSKQELITAPTES 849

  Fly  2341 YY-----KNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRI 2400
            .:     ||.:.|:....|::: |..|:::|.:.::|||....||:|:..|....:.|.|:||.:
plant   850 RFQVDVEKNWVESSKITALLEE-LEGLRSSGSKSILFSQWTAFLDLLQIPLSRNNFSFVRLDGTL 913

  Fly  2401 RGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQ 2465
            ....|::.:..:|:.|| ..|.|:..||||:|||||||....:.|..|||..:.||..|.|||||
plant   914 SQQQREKVLKEFSEDGS-ILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMRIHRIGQ 977

  Fly  2466 RKMVKIYRLLCRNTYEREM 2484
            .|.|||.|.:.:.|.|..|
plant   978 TKEVKIRRFIVKGTVEERM 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	53/331 (16%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	9/81 (11%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	13/63 (21%)
		PLN03142	2029..>2606	CDD:215601	161/674 (24%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
RAD5	NP_197667.1	UBA_like_SF	9..48	CDD:473871	8/43 (19%)
		HIRAN	116..224	CDD:400928	23/143 (16%)
		HepA	<339..1011	CDD:440319	164/696 (24%)
		RING_Ubox	789..842	CDD:473075	3/52 (6%)