Protein Alignment kis and CHR40

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_189077.1
• Gene: CHR40 / 822023
• AraportID: AT3G24340
• Length: 1132
• Species: Arabidopsis thaliana
• Alignment Length: 1255
• Identity: 284/1255 - (22%)
• Similarity: 465/1255 - (37%)
• Gaps: 325/1255 - (25%)

  Fly  1440 DPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLS-------------------AKALKKRR 1485
            |..|..:||.|.|:.:......|..:|.|..:...||.                   :...||||
plant     2 DMTSCVARRTRSRTESYLNSILNKSKGISGEEEDQSLGCVNSRTEKRRVNMRDACSPSPRKKKRR 66

  Fly  1486 NRGRIVPESDGEDDTLDRTPPPSPPPDSEMDSNKRRSSRNTQRKKY-IDDVMLRFSDDENSLLVA 1549
            .|     :.|.:|....||..|....|   |.|...:|.|.|.|.: ..|.:..|..|:.:|
plant    67 RR-----KDDDDDVVFVRTEYPEGKRD---DENVGSTSGNLQSKSFDFGDRVCDFDADDRNL--- 120

  Fly  1550 SPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGE-EKSNLPLDESSQLEASSSTSAVA 1613
                   .....|||.|...|           .|....||. ::.|..:::...:.::|..|
plant   121 -------GCEEKASNFNPIDD-----------DDDVVFVGTVQRENDHVEDDDNVGSASVIS--- 164

  Fly  1614 EKERQISTDAANAAMSSKPNYVYINTGDEDSMVV--------QLVLAMRMGKR--ELILDKPKEK 1668
              .|....|..:|.:|.|.|  .::..|:|.:|.        |.|..:..|..  :::||....:
plant   165 --PRVCDFDEDDAKVSGKEN--PLSPDDDDDVVFLGTIAGENQHVEDVNAGSEVCDILLDDANLR 225

  Fly  1669 APE------------PKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVD 1721
            ..|            ...|:|:..|:|..||..|     :..||.:    ||.|:.::..|.:.|
plant   226 GEEKTYVSDEVVSLSSSSDDEEDPLEELGTDSRE-----EVSGEDR----DSGESDMDEDANDSD 281

  Fly  1722 SKE-ESEPDDSKKSDEDNKDKDKMEVDDEVG--KSDK--ESKPEE------QSETVKTEENSKAI 1775
            |.: ..|..||  ||.::.|.|.:..:||.|  :.|.  |..|.|      :|.|.:.:.|...|
plant   282 SSDYVGESSDS--SDVESSDSDFVCSEDEEGGTRDDATCEKNPSEKVYHHKKSRTFRRKHNFDVI 344

  Fly  1776 EEDKSSTVLTADHAKEPETVLEKM-EVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATT-EKNKE 1838
            .....|.:.:.|..||.....:|: |||.:    :..|.: |.|.||..:...|.|..: .:.:|
plant   345 NLLAKSMLESKDVFKEDIFSWDKIAEVDSR----EDPVVR-ESSSEKVNEHGKPRERRSFHRVRE 404

  Fly  1839 SLEIEGEK----ERVKEGEESVKKENDEKTEADME-NKPEPVFIDVEEYFVKYRNFSYLHCEWRT 1898
            ...:.||.    |::.:|||::....::....::. ...|||.|:                  :|
plant   405 KNHLNGESFYGGEKLCDGEETINYSTEDSPPLNLRFGCEEPVLIE------------------KT 451

  Fly  1899 EEELLKGDRRVAAKIRRFQQKQS--QQLNIFENIEDEPFNQDFTEVDRVLDMSVH---TDETSGE 1958
            |||               ::..|  :.:|:...:|....:......|.:.....|   .|:..|.
plant   452 EEE---------------KELDSLWEDMNVALTLEGMHSSTPDKNGDMLCSKGTHDFVLDDEIGL 501

  Fly  1959 TTKHYLVKWKSLPYEDCTWELEEDVD----NDKIEQYLRFNK---------IPQRSEWKSKKRPH 2010
            ...|            |.:...|..|    .||....:..||         :|.|.|:.:.   .
plant   502 KCVH------------CAYVAVEIKDISPAMDKYRPSVNDNKKCSDRKGDPLPNRLEFDAS---D 551

  Fly  2011 PE------------LWKKLEKTPVYKGG--NSLRPYQLEGLNWLKFSWYN--------------- 2046
            |.            :|:       |..|  ::|.|:|.||   .:|.|.|
plant   552 PSSFVAPLDNIEGTVWQ-------YVPGIKDTLYPHQQEG---FEFIWKNLAGTTKINELNSVGV 606

  Fly  2047 --THNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVY-- 2107
              :..||::.:.|.|||..::.|:.|..:.......:||||.:.:..|:.|...| ::|:..|
plant   607 KGSGGCIISHKAGTGKTRLTVVFLQSYLKRFPNSHPMVIAPATLMRTWEDEVRKW-NVNIPFYNM 670

  Fly  2108 ----------------------HGSVTSKQMIQ----------DYEYYYKTESGKVLKEPIKFNV 2140
                                  |.|:...:::.          .|..|.|..:.|..:....|..
plant   671 NSLQLSGYEDAEAVSRLEGNRHHNSIRMVKLVSWWKQKSILGISYPLYEKLAANKNTEGMQVFRR 735

  Fly  2141 LITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISEL 2205
            ::          ::|..    |.|:||.|..:|::..:.:.|.::..|.|:.||||..|||..||
plant   736 ML----------VELPG----LLVLDEGHTPRNQSSLIWKVLTEVRTEKRIFLSGTLFQNNFKEL 786

  Fly  2206 FSLLNFLEPSQ---FSSQEEFMS------EFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAP 2261
            .::|....|:.   .||:...:|      |.|.:..|..:..|:|::...:.......:::||..
plant   787 SNVLCLARPADKDTISSRIHELSKCSQEGEHGRVNEENRIVDLKAMIAHFVHVHEGTILQESLPG 851

  Fly  2262 KEETIIEVELTNIQKKYYRGI-LEQN-FSFLKKGTTSANIPNLMNTMMELRKCC---------IH 2315
            ..:.::.:.....|||....| ..|| |.|..|.:..:..|:|.       .||         |.
plant   852 LRDCVVVLNPPFQQKKILDRIDTSQNTFEFEHKLSAVSVHPSLY-------LCCNPTKKEDLVIG 909

  Fly  2316 PYLLNGAEEQIQYDFKSQHGEDPESYYKNLILSAGKMVLIDKLLPKLKANG---HRVLIFSQMVR 2377
            |..|                    ...|.|.|...:.|....|:..::.:|   .:||::||.:.
plant   910 PATL--------------------GTLKRLRLKYEEGVKTKFLIDFIRISGTVKEKVLVYSQYID 954

  Fly  2378 CLDILEDYLVYRKYPFE-----RIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTA 2437
            .|.::.:.|:......|     .:.|::....||..||.::||.|...|.|..|||...||:|..
plant   955 TLKLIMEQLIAECDWTEGEQILLMHGKVEQRDRQHMIDNFNKPDSGSKVLLASTKACSEGISLVG 1019

  Fly  2438 ADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSM 2502
            |..|:|.|..|||..:.||.:|..||||::.|.||.|:.::|.|...:.|.|.|..:.:.|..|.
plant  1020 ASRVVILDVVWNPSVESQAISRAFRIGQKRAVFIYHLMVKDTSEWNKYCKQSEKHRISELVFSST 1084

  Fly  2503 NTQGSKDGNNKQLSKKEIED 2522
            | :..|..||:.:||..|.|
plant  1085 N-EKDKPINNEVVSKDRILD 1103

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171	18/78 (23%)
		PTZ00121	<1419..1923	CDD:173412	122/545 (22%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	11/67 (16%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	10/64 (16%)
		PLN03142	2029..>2606	CDD:215601	141/573 (25%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
CHR40	NP_189077.1	HepA	<571..1082	CDD:440319	133/555 (24%)
		DEXHc_ATRX-like	577..830	CDD:350765	59/270 (22%)