Protein Alignment kis and ATCHR12

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_187252.2
• Gene: ATCHR12 / 819772
• AraportID: AT3G06010
• Length: 1102
• Species: Arabidopsis thaliana
• Alignment Length: 1248
• Identity: 326/1248 - (26%)
• Similarity: 520/1248 - (41%)
• Gaps: 323/1248 - (25%)

  Fly  1502 DRTPP-PSPPPDSEMDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNS 1565
            |.:|| |:.||     :||         ..|..|:|..|   |::||...|            :.
plant    62 DVSPPLPTSPP-----ANK---------APYGADLMGEF---EDALLKQRP------------DC 97

  Fly  1566 NAGSD-VEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMS 1629
            .:||. ::..:.::.:.   .|....|...||......|:|.........|.|::......|.
plant    98 ESGSRLIQLLDNRNKSH---IQRRLSELEELPSTRGEDLQAKCLLELYGLKLRELQGKVRTAV-- 157

  Fly  1630 SKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEK 1694
            |...::.:|..|..|.|               .|....:.|.|
plant   158 SSEFWLRLNCADVSSQV---------------FDWGMMRLPRP---------------------- 185

  Fly  1695 FKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDD-----EVGKSD 1754
            |...|              :..|||.|.:...:.|..:.|..:.::|:.:|...     ||..:.
plant   186 FYGVG--------------DPFAMEADDQFRKKRDAERLSRLEEEEKNLIETAKRKFFAEVLNAV 236

  Fly  1755 KESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPE--TVLEKMEVDEKANDDQSAVSKAEG 1817
            :|.:.:.|:...:..:.:..::         |.|.::.:  |..||:.:....:|||.|..|.
plant   237 REFQLQIQATQKRRRQRNDGVQ---------AWHGRQRQRATRAEKLRLMALKSDDQEAYMKL-- 290

  Fly  1818 SDEKSTDDSNPEEATT---EKNKESLEIEGEKERVK-----EGEESVKKENDEKTEADMENKPEP 1874
                 ..:|..|..||   |.||....:....:|.|     ||.:.:|....:.:|.|.. :.||
plant   291 -----VKESKNERLTTLLEETNKLLANLGAAVQRQKDAKLPEGIDLLKDSESDLSELDAP-RSEP 349

  Fly  1875 VFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDF 1939
            :                        ::||                ..|.::|.|:..::..| |.
plant   350 L------------------------QDLL----------------PDQDIDITESDNNDDSN-DL 373

  Fly  1940 TEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWK 2004
            .|..|..:.::|:
plant   374 LEGQRQYNSAIHS---------------------------------------------------- 386

  Fly  2005 SKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVH 2069
                    :.:|:.:.|....|..||.||||||.|:...:.|..|.|||||||||||||:::.:.
plant   387 --------IQEKVTEQPSLLEGGELRSYQLEGLQWMVSLFNNNLNGILADEMGLGKTIQTISLIA 443

  Fly  2070 SVYE-YGIRGPFLVIAPLSTIPNWQREFEGWT-DMNVVVYHGSVTSKQMIQDYEYYYKTESGKVL 2132
            .:.| .|:.||:|::||.:.:|||..||..|. .:...:|.|               :.|..|.:
plant   444 YLLENKGVPGPYLIVAPKAVLPNWVNEFATWVPSIAAFLYDG---------------RLEERKAI 493

  Fly  2133 KEPI----KFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNC----KLLEGLRQLNLEH 2189
            :|.|    |||||||.:::|:.|...||...|...::||.|||||...    .||.|.|   ::.
plant   494 REKIAGEGKFNVLITHYDLIMRDKAFLKKIEWYYMIVDEGHRLKNHESALAKTLLTGYR---IKR 555

  Fly  2190 RVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFG---------SLRTEEE---VNKLQAL 2242
            |:||:|||:||::.||:||||||.|..|:|.:.|...|.         ||..|||   :::|..:
plant   556 RLLLTGTPIQNSLQELWSLLNFLLPHIFNSVQNFEEWFNAPFADRGNVSLTDEEELLIIHRLHHV 620

  Fly  2243 LKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANIPNLMNTMM 2307
            ::|.:|||.||:|||.|..|.:.|::.:::..||.||:.:.:.....|:.|  |....:|.|..|
plant   621 IRPFILRRKKDEVEKFLPGKTQVILKCDMSAWQKVYYKQVTDMGRVGLQTG--SGKSKSLQNLTM 683

  Fly  2308 ELRKCCIHPYLLNGAEEQIQYDFKSQHGEDPESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIF 2372
            :|||||.||||..|.:..:        .:.||     ::.::||..|:|:|||||:..|||:|:|
plant   684 QLRKCCNHPYLFVGGDYNM--------WKKPE-----IVRASGKFELLDRLLPKLRKAGHRILLF 735

  Fly  2373 SQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTA 2437
            |||.|.:|:||.||....|.:.|:||..:.:.|...:.::::|.|..|:|||.|:|||||:||..
plant   736 SQMTRLIDVLEIYLTLNDYKYLRLDGTTKTDQRGLLLKQFNEPDSPYFMFLLSTRAGGLGLNLQT 800

  Fly  2438 ADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQS- 2501
            ||||||:|||||||.|.||:.|.|||||:|.|:::.|:...:.|..:.::|..|:|:|..|:|:
plant   801 ADTVIIFDSDWNPQMDQQAEDRAHRIGQKKEVRVFVLVSVGSVEEVILERAKQKMGIDAKVIQAG 865

  Fly  2502 -MNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDN----------AGDKF-CEEDIDSILKRR 2554
             .||..:.....:.|     |::::||......|..:          :.|:| ..|.:|...:|:
plant   866 LFNTTSTAQDRREML-----EEIMRKGTSSLGTDVPSEREINRLAARSEDEFWMFERMDEERRRK 925

  Fly  2555 ------------------TQVITMESEKGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDP 2601
                              |.....|......|...|......|.:|...|.....:|.|.|:...
plant   926 ENYRARLMQEQEVPEWAYTTQTQEEKLNNGKFHFGSVTGKRKRKEIVYSDTLSELQWLKAVESGE 990

  Fly  2602 DACE-------RDETEDLVLSEPRRRTQIKRYGHEDVMELNSEESSNENSDEEGGIGLRSRRRKE 2659
            |..:       |:|.    .|..:..|..|.......:...:.|...|..:||....:..::|.:
plant   991 DLSKLSMRYNRREEN----ASNTKTSTSKKVIESIQTVSDGTSEEDEEEQEEERAKEMSGKQRVD 1051

  Fly  2660 KRDRAREKKGNDE 2672
            |.:. .|::|.:|
plant  1052 KSEE-EEEEGEEE 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	77/437 (18%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	9/66 (14%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	4/57 (7%)
		PLN03142	2029..>2606	CDD:215601	224/636 (35%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
ATCHR12	NP_187252.2	PLN03142	390..>911	CDD:215601	211/558 (38%)
		SnAC	916..983	CDD:464219	10/66 (15%)