Protein Alignment kis and CHR8

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_001324142.1
• Gene: CHR8 / 816391
• AraportID: AT2G18760
• Length: 1246
• Species: Arabidopsis thaliana
• Alignment Length: 1209
• Identity: 300/1209 - (24%)
• Similarity: 469/1209 - (38%)
• Gaps: 364/1209 - (30%)

  Fly  1674 QDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAM-EVDSKEESEPDDSKKSDED 1737
            :|.|:..|||| |.||:.||....|.:|    |..|.|.|.||:. |:.:|..:.
plant    21 EDLEQKILDEA-TKKPDNDEGGSVEEKS----TQLEGTNLLSSSQNELLNKLRAV---------- 70

  Fly  1738 NKDKDKMEVD---------DEVGKSDKESKPEEQSETVKTEENS---KAIEEDKSSTVLTADHAK 1790
                 |.|:|         ||:. ::|..|.:::|:.......|   .|:..|:..::      |
plant    71 -----KFEIDAVASTVENVDEIA-AEKGLKKDDESDLQGLHSGSALQHALATDRLRSL------K 123

  Fly  1791 EPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEES 1855
            :.:..|||            .::...|....|:.|.........|.|.||     |.::||..:.
plant   124 KRKIQLEK------------ELTGLHGQSASSSADHGNLLRDLVKEKPSL-----KRKLKEIRKP 171

  Fly  1856 VKKEND--------EKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAK 1912
            .:::..        |.|:.|      .||......||          |...:|.:.||......|
plant   172 SRRDGKKVKVVSFREDTDFD------AVFDGASAGFV----------ETERDELVRKGILTPFHK 220

  Fly  1913 I----RRFQQK-QSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPY 1972
            :    ||.||. .|...|:.|. :||  |:|.:.:||.: .|:.....:..|||  |:..:.||
plant   221 LDGFERRLQQPGPSNSRNLPEG-DDE--NEDSSIIDRAV-QSMSLAAKARPTTK--LLDAEDLP- 278

  Fly  1973 EDCTWELEEDVDNDKIE----QYLRFNKI------------PQRSEWKSKK-RPHPE-LWKKL-- 2017
                          |:|    .:.|..|:            .:::..|||| ||.|| .|:|.
plant   279 --------------KLEPPTAPFRRLRKLYKTPNSPDNEAKKRKAGKKSKKTRPLPEKKWRKRIS 329

  Fly  2018 ----------------------------------------------------------------- 2017
                                                                             
plant   330 REDSSLQGSDKAVILDLPDVEISHVINAMLLSDKSQQFLPMLSKFFFFPHLSLCKPTSYDVDSCC 394

  Fly  2018 -----------------------------EKTPV-YKGG--------NSLRPYQLEGLNWLKFSW 2044
                                         |::.| .:||        ..|..||..|:.||
plant   395 NVSGDGRRILTTSSCEEEELDDFDDADDNERSSVQLEGGLNIPECIFRKLFDYQRVGVQWL---- 455

  Fly  2045 YNTHNC-----ILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGW-TDMN 2103
            :..| |     |:.||||||||||.|:|:.|::...:..|.::|.|::.:..|:||.:.| .|.:
plant   456 WELH-CQRAGGIIGDEMGLGKTIQVLSFLGSLHFSKMYKPSIIICPVTLLRQWRREAQKWYPDFH 519

  Fly  2104 VVVY--------HGSVTSKQMIQDYEYYYKTES----------------GKVLKEPIKFNVLITT 2144
            |.:.        ||....|....||:.....:|                .:||..  :..:||||
plant   520 VEILHDSAQDSGHGKGQGKASESDYDSESSVDSDHEPKSKNTKKWDSLLNRVLNS--ESGLLITT 582

  Fly  2145 FEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLL 2209
            :|.:......|....|...|:||.||::|.|..:....:||...||::::|.|:||.::||:||.
plant   583 YEQLRLQGEKLLNIEWGYAVLDEGHRIRNPNSDITLVCKQLQTVHRIIMTGAPIQNKLTELWSLF 647

  Fly  2210 NFLEPSQFSSQEEFMSEF------GSLRTEEEVN---------KLQALLKPMMLRRLKDDVEKSL 2259
            :|:.|.:......|.:||      |.......:.         .|:.|:.|.:|||:|.||...|
plant   648 DFVFPGKLGVLPVFEAEFSVPITVGGYANASPLQVSTAYRCAVVLRDLIMPYLLRRMKADVNAHL 712

  Fly  2260 APKEETIIEVELTNIQKKYYRGIL-----EQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLL 2319
            ..|.|.::...||..|:..||..|     ||.|...:......::         :||.|.||.||
plant   713 TKKTEHVLFCSLTVEQRSTYRAFLASSEVEQIFDGNRNSLYGIDV---------MRKICNHPDLL 768

  Fly  2320 NGAEEQIQYDFKSQHGEDPESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILED 2384
            .........|:     .:||        .:|||.::.::|...|..|||||:|||..:.|||||.
plant   769 EREHSHQNPDY-----GNPE--------RSGKMKVVAEVLKVWKQQGHRVLLFSQTQQMLDILES 820

  Fly  2385 YLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWN 2449
            :||..:|.:.|:||......|...||.::. ..|.|||:|.||.||||.|||.|:.|||:|.|||
plant   821 FLVANEYSYRRMDGLTPVKQRMALIDEFNN-SEDMFVFVLTTKVGGLGTNLTGANRVIIFDPDWN 884

  Fly  2450 PQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQ 2514
            |.||:||:.|..||||:|.|.:|||:.|.|.|.:::.:...|..|...:|:  |.|     ..:.
plant   885 PSNDMQARERAWRIGQKKDVTVYRLITRGTIEEKVYHRQIYKHFLTNKILK--NPQ-----QRRF 942

  Fly  2515 LSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITM---------ESEKGSTFSK 2570
            ...::::||.       ::.||  ||.....:..:|..:..:.|.:         ||:......|
plant   943 FKARDMKDLF-------ILKDD--GDSNASTETSNIFSQLAEEINIVGVQSDKKPESDTQLALHK 998

  Fly  2571 ASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG------HE 2629
            .: ..|..::|:.:.|     |..:.:|        :||..|       ::....:|      |:
plant   999 TA-EGSSEQTDVEMTD-----KTGEAMD--------EETNIL-------KSLFDAHGIHSAVNHD 1042

  Fly  2630 DVMELNSEESSNENSDEEGGIGLRSRR--RKEKRDRARE 2666
            .:|..|.||.......:...:..|:..  |:.:..|:||
plant  1043 AIMNANDEEEKMRLEHQASQVAQRAAEALRQSRMLRSRE 1081

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	63/274 (23%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	15/78 (19%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	13/61 (21%)
		PLN03142	2029..>2606	CDD:215601	190/635 (30%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
CHR8	NP_001324142.1	HepA	<435..923	CDD:440319	169/517 (33%)
		CSB_WHD	1179..1245	CDD:439329