DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kis and CHD9

DIOPT Version :9

Sequence 1:	NP_001137761.1	Gene:	kis / 33185	FlyBaseID:	FBgn0266557	Length:	5517	Species:	Drosophila melanogaster
Sequence 2:	XP_005256225.1	Gene:	CHD9 / 80205	HGNCID:	25701	Length:	2898	Species:	Homo sapiens

Alignment Length:	4155	Identity:	1197/4155 - (28%)
Similarity:	1664/4155 - (40%)	Gaps:	1446/4155 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   989 VSKTQDITLSTELPTIQDD----LQEKPT----AEMEQT---------QLGQSLGDLSKSLLEEP 1036
            ||...::.|..|...:..|    :|..||    .:.||.         .:.||.|..::.:|
Human    33 VSLVDELNLGAEFEPLHIDSLNHVQGTPTHQKMTDFEQLNQFDSIKFHHVNQSFGSPAEHVL--- 94

  Fly  1037 KTVEESGEDKSQSAPGVAPPADPIIPVTQPPQQQMPPI--GMPM--HPIAP------GYEAQAQG 1091
                         :|.......||.|..| |....|.:  |.||  |..|.      |.....||
Human    95 -------------SPHSQFNCSPIHPQNQ-PNGLFPDVSDGSPMWGHQTATTISNQNGSPFHQQG 145

  Fly  1092 QGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQELYC-----------MPPGHELQHQDKL 1145
            ..|            .|:.....:...:.|..|...|:..|           :.||     |:.|
Human   146 HSH------------SMHQNKSFVAHHDFALFQANEQQTQCTSLRSQQNRNNLNPG-----QNSL 193

  Fly  1146 MRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTT-------- 1202
            .:.:..:|:...|.||            .|.||......|   :||.:...|.|.|:
Human   194 SQSKNFMNVSGPHRVN------------VNHPPQMTNASN---SQQSISMQQFSQTSNPSAHFHK 243

  Fly  1203 ------GRGRGKSANKPRKPRAKKGEKAQVGQQQDLMD--------ISGNVAMGAANAVSSIPTT 1253
                  |...|.|.|.         ....|...|....        ||.|..:.::..::|..|.
Human   244 CSSHQEGNFNGPSPNM---------TSCSVSNSQQFSSHYSFSSNHISPNSLLQSSAVLASNHTN 299

  Fly  1254 QLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDV-HSANELDTSTDGSGKKKKPRKPRTPKDPN 1317
            |      .::...|..|      :|...|...:.. |..|                 |.|..:.|
Human   300 Q------TLSDFTGSNS------FSPHRGIKQESTQHILN-----------------PNTSLNSN 335

  Fly  1318 K--------PPRDRTPKAKKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGEGSEVED 1374
            .        |..:.:.....|...|.|:..:           |..:..:..|..|..| .|.:|:
Human   336 NFQILHSSHPQGNYSNSKLSPVHMNFPDPVD-----------SGTQMGHFNDHVETNG-FSSLEE 388

  Fly  1375 NKPLVPKAGSADGEAETTSGGTGVDGES-------PDYDDIPVSKIPRGSNEDEKEAEAGDETVD 1432
            |  |:.:..|      .|...||:|.|.       |.:|                |:..|.:...
Human   389 N--LLHQVES------QTEPFTGLDPEDLLQEGLLPHFD----------------ESTFGQDNSS 429

  Fly  1433 SVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGE 1497
            .:.|...|...|.....|....|:::..:.:....|:..|...|        .:|..:
Human   430 HILDHDLDRQFTSHLVTRPSDMAQTQLQSQARSWHSSFSNHQHL--------HDRNHL------- 479

  Fly  1498 DDTLDRTPPPSPPPDSE------MDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDK 1556
              .|.|.||.|...|..      .::..|..|...||||                 |.|..|::|
Human   480 --CLQRQPPSSKKSDGSGTYTKLQNTQVRVMSEKKQRKK-----------------VESESKQEK 525

  Fly  1557 KPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQIST 1621
               ||...|.|   :.|           |:|.||.  |:|...|.:...::|.....||:
Human   526 ---ANRIISEA---IAK-----------AKERGER--NIPRVMSPENFPTASVEGKEEKK----- 566

  Fly  1622 DAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDE--A 1684
               ...|.|||.                             ||..:|.....:.:||:::.:  .
Human   567 ---GRRMKSKPK-----------------------------DKDSKKTKTCSKLKEKTKIGKLII 599

  Fly  1685 TTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDE 1749
            |..|     |.|.:.||..:::|:|:.                |..:.| |:|::.:
Human   600 TLGK-----KQKRKNESSDEISDAEQM----------------PQHTLK-DQDSQKR-------- 634

  Fly  1750 VGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSK 1814
              :|:::.|.::.:|.:   |..::.||.|.|..:..:.|..|.....::.|:..:.:|.:.|.|
Human   635 --RSNRQIKRKKYAEDI---EGKQSEEEVKGSMKIKKNSAPLPGEQPLQLFVENPSEEDAAIVDK 694

  Fly  1815 AEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDV 1879
            ...|                                   .:||||..           ..|.||.
Human   695 ILSS-----------------------------------RTVKKEIS-----------PGVMIDT 713

  Fly  1880 EEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDR 1944
            ||:||||:|:|||||||.|||:||| |:|:..||:||:.:|:|:.:.|.::|:||||.|:.||||
Human   714 EEFFVKYKNYSYLHCEWATEEQLLK-DKRIQQKIKRFKLRQAQRAHFFADMEEEPFNPDYVEVDR 777

  Fly  1945 VLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRP 2009
            ||::|...|:.:||...:|||||.||||||.||||:||||..|||::.:..  ..|.:.:...||
Human   778 VLEVSFCEDKDTGEPVIYYLVKWCSLPYEDSTWELKEDVDLAKIEEFEQLQ--ASRPDTRRLDRP 840

  Fly  2010 HPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEY 2074
            ...:|||::::..||.||.||.|||||||||.|:|||..||||||||||||||||:||::.:...
Human   841 PSNIWKKIDQSRDYKNGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEILLT 905

  Fly  2075 GIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFN 2139
            |||||||:|||||||.||:|||..|||:||||||||:.|:||||.||.|::...|::::...:|.
Human   906 GIRGPFLIIAPLSTIANWEREFRTWTDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQ 970

  Fly  2140 VLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISE 2204
            .:|||||||:....:|.|..||..:|||||||||:||||||||:.:||||:|||:||||||.:.|
Human   971 AIITTFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEE 1035

  Fly  2205 LFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEV 2269
            |||||:||||.:|.|:..||.|||.|:|||:|.||||:||||||||||:||||.|||||||||||
Human  1036 LFSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEETIIEV 1100

  Fly  2270 ELTNIQKKYYRGILEQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQH 2334
            |||||||||||.|||:|||||.||....|:|||:||||||||||.||||:.||||:|..:|:..:
Human  1101 ELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIKGAEEKILGEFRDTY 1165

  Fly  2335 GEDPESYY-KNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDG 2398
            ......:: :.:|.||||:|||||||||:||.||:||||||||||||||||||::::|.:|||||
Human  1166 NPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDG 1230

  Fly  2399 RIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRI 2463
            |:||||||.||||:|||.||||||||||:|||||||||||||.||:|||||||||||||||||||
Human  1231 RVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRI 1295

  Fly  2464 GQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGA 2528
            ||.|.||:|||:.||:|||||||:||:||||||||||||:.:.|..|..:|||||||||||::||
Human  1296 GQNKAVKVYRLVTRNSYEREMFDRASLKLGLDKAVLQSMSGRESNVGGIQQLSKKEIEDLLRRGA 1360

  Fly  2529 YGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTK 2592
            |||:|::::.|.||||||||.||.|||:.||:||| :||||:||||.|||||:||::|||:||.|
Human  1361 YGAIMEEEDEGSKFCEEDIDQILLRRTKTITIESEGRGSTFAKASFVASGNRTDISLDDPNFWQK 1425

  Fly  2593 WAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG--HEDVMELNSEESSNENSDEEGGIGLRSR 2655
            ||||.:||.:|.  .....||:..||.|.|.:.:.  .:::.||:..||..:
Human  1426 WAKKAEIDIEAI--SGRNSLVIDTPRIRKQTRPFSATKDELAELSEAESEGD------------- 1475

  Fly  2656 RRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLEL 2720
             .|.|..|           |.:|.            ..:.::|||:|||.||.:|||||.|:|..
Human  1476 -EKPKLRR-----------PCDRS------------NGYGRTECFRVEKNLLVYGWGRWREILSH 1516

  Fly  2721 GQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPR 2785
            |:|||...:.|||...|.:|.|||..|:||||||.||||||||||||:.::: ::|.||...|||
Human  1517 GRFKRQLNEHDVEIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTREL-QNHLGLSAPVPR 1580

  Fly  2786 GRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPN 2850
            ||.|.|       |.|                  ::|:.|....:
Human  1581 GRKGKK-------VKT------------------QTSSFDIQKAE-------------------- 1600

  Fly  2851 HWSKKEKYDADAYLEG-AYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPI-R 2913
             |.:  ||:.:..|:. .||||:..|.||||||||||||::.||||:..|::.|....|::.: .
Human  1601 -WLR--KYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLYYLKQEVIGNECQKVFDGVDASDIDVWV 1662

  Fly  2914 PPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPI 2978
            |.|...:||:.||: ...|||||:|.:|||.|.|..:||||.|||:..||   ..|:.||.:
Human  1663 PEPDHSEVPAEWWD-FDADKSLLIGVFKHGYEKYNTIRADPALCFLERVG---KPDEKAVAA--- 1720

  Fly  2979 NEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTE 3043
             |..||. :.|||                          :.|||
Human  1721 -EQRAND-YMDGD--------------------------VEDPE--------------------- 1736

  Fly  3044 SENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPA 3108
                        ||..                              |.:.|:|.:         .
Human  1737 ------------YKPA------------------------------PAIFKDDIE---------D 1750

  Fly  3109 DSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTE 3173
            |.|||                |:|.|             :.||...:            ||||
Human  1751 DVSSP----------------GDLVI-------------ADGDGQLM------------EGDK-- 1772

  Fly  3174 SCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTV 3238

Human  1773 ----------------------------------------------------------------- 1772

  Fly  3239 AAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSM 3303
                   ..||:...|.|||||:||||||..|..:::..|           |..||||
Human  1773 -------VYWPTQSALTTRLRRLITAYQRTNKNRQIQQIQ-----------PTFSVPT------- 1812

  Fly  3304 QMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGA 3368

Human  1813 ----------------------------------------------------------------- 1812

  Fly  3369 GVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQ 3433
                        |:|..|.....:|.              .|..|:|||
Human  1813 ------------SVMQPIYEEATLNP--------------KMAAKIERQ---------------- 1835

  Fly  3434 LIPKKWNRREEYEFLRVLTGYGVDLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDYYK 3498
               ::|.||||.:|.||::.:||   |..|   ..|..   |||||:.||.|.:|:|::|..|..
Human  1836 ---QRWTRREEADFYRVVSTFGV---VFDP---DRGQF---DWTKFRAMARLHKKTDDSLEKYLY 1888

  Fly  3499 VFVAMCKRQAGLKLSESERGLEGIIEEIEKEHAKLILDRLEVLAKLREVA-RNPMLEERLKLCTK 3562
            .|::||:|...|...|........|:.|.:|.|...|.|:|:|.|:||.| |:|.|.||||||..
Human  1889 AFMSMCRRVCRLPSKEELVDPNIFIQPITEERASRTLYRIELLRKVREQALRHPQLFERLKLCHP 1953

  Fly  3563 NADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAF 3627
            |.|.|.|||.|.||::|:....|||:.|::..|..||..||
Human  1954 NPDLPVWWECGPHDRDLLIGAAKHGVSRTDYHILRDPELSF------------------------ 1994

  Fly  3628 NAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEI 3692
                    .||:::.:..|.|.:..:.                .|:....|....||:|.:
Human  1995 --------MAAQRNYSQSKMAHSRTST----------------PLLQQYQVALSASPLTSL---- 2031

  Fly  3693 KSEESPEKHDTADNLEDKNSDAEESTKIKG---KEDFNPETTEKEALDESTNLNKDKSSTETLVP 3754
                        ..|.|......|..|:|.   ||:  |:::|:|::          ||.||..
Human  2032 ------------PRLLDAKGIILEEMKVKSENLKEE--PQSSEEESM----------SSVETRT- 2071

  Fly  3755 EIEDSKPSEDKMEVEELPVAENGEKEGSPEKCSDAEDKKF----SEEKPSSPAVPDGKV----SE 3811
             :..|:|...|..|  ||.|...:|.|.  ||.  .|::.    :|....:||....:|    ||
Human  2072 -LIKSEPVSPKNGV--LPQATGDQKSGG--KCE--TDRRMVAARTEPLTPNPASKKPRVHKRGSE 2129

  Fly  3812 MEADEAAPNTEENCS--GDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIESE 3874
            ..:|..:.:...:||  ..|.|....|               |:.::......:.....:|..|.
Human  2130 SSSDSDSDSERSSCSSRSSSSSSSSSC---------------SHSRSGSSSSSSSSCSSASSSSS 2179

  Fly  3875 PSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKE-----KAVEEECKKQAAELK 3934
            .|..|.:        ...|:..::        ||.|::|..|..|     ||.:||.....:..:
Human  2180 SSTSSSS--------SSSSSSSEE--------SDSDEEEAQKRAESTTHMKAYDEESVASLSTTQ 2228

  Fly  3935 ARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSKYSAFATC 3999
            ....|...:...|.:...:.:....:....|.||..:..|:..|...|..|.||     ||
Human  2229 DETQDSFQMNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGKWP-----SA---- 2284

  Fly  4000 KGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQ 4064
                                 |||...:.:                       ||..:|..
Human  2285 ---------------------RRSYDANTV-----------------------ASFYTTKL---- 2301

  Fly  4065 VTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSV 4129
                          ||:                           ||    |||     ..|..||
Human  2302 --------------LDS---------------------------PG----AAT-----EYSDPSV 2316

  Fly  4130 PS-AGSGVGKKRKRHIAIDVETERAKL--HALLNSSTMAPKDWESEIANMEALSGSSGRGRGGNS 4191
            |: .|:||   ::.|   |..|:.:|:  |......|:..||                  .||
Human  2317 PTPPGAGV---KEEH---DQSTQMSKVKKHVREKEFTVKIKD------------------EGG-- 2355

  Fly  4192 SASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSS 4256
                          ..|:.|..|.       |.|.|.......:.....|.::   ..|:|||.:
Human  2356 --------------LKLTFQKQGL-------AQKRPFDGEDGALGQQQYLTRL---RELQSASET 2396

  Fly  4257 GAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKK 4321
            ..::..:    |:|...:|:.       |::|....:.|             .:|::.|.:.|:|
Human  2397 SLVNFPK----SIPVSGTSIQ-------PTLGANGVILD-------------NQPIVKKRRGRRK 2437

  Fly  4322 LDE---------------IVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPA-NLQSSSNQQS 4370
            ..|               :.|||::: :..|..:|:|..::...||.:.|..|. ||
Human  2438 NVEGVDIFFFNRNKPPNHVSLGLTSS-QISTGINPALSYTQPQGIPDTESPVPVINL-------- 2493

  Fly  4371 NQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLA 4435
                            |.|:..:|.
Human  2494 ----------------KDGTRLAGD---------------------------------------- 2502

  Fly  4436 QTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTS 4500
                                                            ::|....:.|||.:...
Human  2503 ------------------------------------------------DAPKRKDLEKWLKEHPG 2519

  Fly  4501 PLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGP 4565
                     ||...||.                           ..:.|..:.:.:|::|....|
Human  2520 ---------YVEDLGAF---------------------------IPRMQLHEGRPKQKRHRCRNP 2548

  Fly  4566 -----QNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSP 4625
                 .:|||||.|.:||::..:::||..||.||.|.::|.||..|.|.|:|.:.::.....|
Human  2549 NKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKDLCRFLKENSEYGVAPEWGDVVKQSGFLP-- 2611

  Fly  4626 RPASMESGYG--------SSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSR 4682
                 ||.|.        ...|...|.||.|.::
Human  2612 -----ESMYERILTGPVVREEVSRRGRRPKSGIA------------------------------- 2640

  Fly  4683 QQTAASAALDQAALQFGSLAGLNPSLLAN--LPGLGAFDPKNPLAAFDPKNPLLSMSF-GGMPGM 4744
            :.|||:||....     |::| || ||||  |||:   |.....|.......|.|:.. .|:.||
Human  2641 KATAAAAAASAT-----SVSG-NP-LLANGLLPGV---DLTTLQALQQNLQNLQSLQVTAGLMGM 2695

  Fly  4745 -GNIPGLGNLNNM-NLFAS-LAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQ 4806
             ..:|..|...|| .:|.. |:||.||.||.||                |||......:|:
Human  2696 PTGLPSGGEAKNMAAMFPMLLSGMAGLPNLLGM----------------GGLLTKPTESGT---- 2740

  Fly  4807 AQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPF 4871
                .....|.|..|:.|.::.:.|:.....:.:.:.|.||..:.|   .|.||:|:.||.. |.
Human  2741 ----EDKKGSDSKESEGKTERTESQSSENGGENSVSSSPSTSSTAA---LNTAAAANPLALN-PL 2797

  Fly  4872 LFPNPSLLYPPMGL-GGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQ--------S 4927
            |..|  :|||.|.| .|||                      |:..|.|.|||...|        |
Human  2798 LLSN--ILYPGMLLTPGLN----------------------LHIPTLSQSNTFDVQNKNSDLGSS 2838

  Fly  4928 KSHQSQSKSSQSRNTTASANSAASLMNAMASMGGGASTVTTPSTSASGSGRGRQSSSRNQ 4987
            ||.:.:.:.|:.::......:..|.:|. .|...|:......|.|.|.|.....|.|.|:
Human  2839 KSVEVKEEDSRIKDQEDKGGTEPSPLNE-NSTDEGSEKADASSGSDSTSSSSEDSDSSNE 2897

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	BASP1	1554..1786	CDD:283191	45/233 (19%)
		HepA	1676..2527	CDD:223627	467/853 (55%)
		SDA1	<1693..>1854	CDD:283052	25/160 (16%)
		CHROMO	<1879..1919	CDD:237991	26/39 (67%)
		Chromo	1941..1996	CDD:278797	32/54 (59%)
		DEXDc	2048..2197	CDD:238005	94/148 (64%)
		Helicase_C	2350..2464	CDD:278689	96/113 (85%)
		RR_TM4-6	3728..>3877	CDD:283990	34/158 (22%)
		BRK	4569..4613	CDD:197800	20/43 (47%)
CHD9	XP_005256225.1	COG5048	80..479	CDD:227381	94/529 (18%)
		ETAA1	<164..355	CDD:317720	42/248 (17%)
		CHROMO	692..752	CDD:237991	36/106 (34%)
		Chromo	773..827	CDD:306815	32/53 (60%)
		SNF2_N	811..>1480	CDD:331286	437/686 (64%)
		BRK	2483..2532	CDD:197800	15/196 (8%)
		BRK	2557..2601	CDD:197800	20/43 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	556	1.000	Domainoid score	I240
eggNOG	1	0.900	-	-		E2759_KOG0384
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1539	1.000	Inparanoid score	I94
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001075
OrthoInspector	1	1.000	-	-		oto88594
orthoMCL	1	0.900	-	-		OOG6_100621
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3575
SonicParanoid	1	1.000	-	-		X648
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.750