Protein Alignment kis and Rad54b

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_001034645.1
• Gene: Rad54b / 623474
• MGIID: 3605986
• Length: 886
• Species: Mus musculus
• Alignment Length: 920
• Identity: 230/920 - (25%)
• Similarity: 396/920 - (43%)
• Gaps: 218/920 - (23%)

  Fly  1767 KTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTD----DSN 1827
            |:.:.::.|...:|:    ||.:||    :.||..|.|.         .:|:::...|    .||
Mouse    13 KSFKKTRFIPPGRSN----ADVSKE----ITKMSPDPKL---------FQGAEQSQNDPGVCSSN 60

  Fly  1828 PEEATTEKNKESLEIEGEKERVKEGEE-----SVKKENDEKTEADMENKPEPVFIDVEEYFVKYR 1887
            |           ...||....|.:|..     .|...:.|.||:..:.         ||.....:
Mouse    61 P-----------CPSEGIPREVGDGTRVDPLPPVHSASKEITESKAQE---------EEASSLLK 105

  Fly  1888 NFSYLHCE-WRTEEELLKGDRRVAAKIRRFQQKQSQQLNI-------FENIEDEPFNQDF----T 1940
            .||.:.|: .:.:.:..:||..:..:.|.|..|..:..:|       |:::|:....|..    .
Mouse   106 YFSVVWCKASKKKHKKWEGDAILIVRGRSFTLKDLEGKDIGRGIGYKFKDLENVEEGQTLIIGGK 170

  Fly  1941 EVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKS 2005
            |:: :|......|..||:..:|    ....|....:....:...|.       |..:.|.::.:.
Mouse   171 EIE-ILGTISSDDFNSGKCFQH----GSGSPAVPSSQAARKCFSNP-------FKSVCQSTQAQG 223

  Fly  2006 KK-------------------RP---HPELWKKLEKTPVYKG------GNSLRPYQLEGLNWLKF 2042
            |:                   ||   |..::.: ..:|:...      .:.|||:|.:|:.:|
Mouse   224 KRWNDCRPRHNPCTPNALVMPRPDENHQRMFNR-HCSPIVDVVIDPHLVHHLRPHQKDGIIFL-- 285

  Fly  2043 SWYNTHNC------------ILADEMGLGKTIQSLTFVHSVYEYGIRGPF---------LVIAPL 2086
                 :.|            |||||||||||:|.::.:.::.   .:||:         |::.|.
Mouse   286 -----YECVMGMRAVGKCGAILADEMGLGKTLQCISLIWTLQ---CQGPYGGKPVIKKTLIVTPG 342

  Fly  2087 STIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIK---FNVLITTFEMI 2148
            |.:.||::||:.|.        ||...|....|.::       || :|.|.   .:|||.::||:
Mouse   343 SLVNNWRKEFQKWL--------GSERIKIFTVDQDH-------KV-EEFINSTFHSVLIISYEML 391

  Fly  2149 VTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLE 2213
            :.....:|...:.|.:.||.|||||.:.|....|..|:.|..|:|:|||:||::.|.|:|::|:.
Mouse   392 LRSLDQIKTIPFGLLICDEGHRLKNSSIKTTTALSSLSCEKTVILTGTPVQNDLQEFFALVDFVN 456

  Fly  2214 P------SQF---------------SSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEK 2257
            |      |.:               ||:||  .|.|..|..|    |..|....:|||.::.:.|
Mouse   457 PGILGSLSSYRKIYEEPIIISREPSSSKEE--RELGERRATE----LTRLTGRFILRRTQEVINK 515

  Fly  2258 SLAPKEETIIEVELTNIQKKYYRGIL-EQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNG 2321
            .|.||.|.::......:|.:.||.:| .|:..|..:|... |..:|: .:..|:|.|.||.||..
Mouse   516 YLPPKIENVVFCRPGALQIELYRKLLRSQSVRFCLQGLLE-NSAHLI-CIGALKKLCNHPCLLFS 578

  Fly  2322 AEEQIQYDFKSQHGEDPESYYKNL---ILS---------------AGKMVLIDKLLP---KLKAN 2365
            :.:..::....:..|:     :||   :||               :||:.::.|||.   :|:..
Mouse   579 SVKGKEFSSSCEENEE-----RNLCQGLLSVFPAGYNPLQFSEEESGKLQVLVKLLAVIHELRPT 638

  Fly  2366 GHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGG 2430
             .:|::.|...:.|::||:......|...|:||:...:.||..:|.::...|..|:|||.:||||
Mouse   639 -EKVILVSNYRQTLNVLEEVCKRHGYACARLDGQTPVSQRQHIVDSFNSKYSTDFIFLLSSKAGG 702

  Fly  2431 LGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLD 2495
            :|:||.....:|:||.||||..|:||.:|..|.||:..|.|||||...|.|.:::.:...|.||.
Mouse   703 VGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQGLS 767

  Fly  2496 KAVLQSMNTQGSKDGNNKQLSKKEIEDL--LKKGAYGA---VMDDDNAGDKFCEEDIDS--ILKR 2553
            .||:..     ::...:.|.|.:|:::|  |.:.::..   ::|.:..|:|...||...  :..|
Mouse   768 GAVVDL-----TRSSEHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGEKGHTEDASEGPVASR 827

  Fly  2554 RTQVITMESE 2563
            :.|....:|:
Mouse   828 QCQFGPQKSD 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	34/165 (21%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	14/72 (19%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	9/61 (15%)
		PLN03142	2029..>2606	CDD:215601	177/609 (29%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
Rad54b	NP_001034645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		24/109 (22%)
		HepA	<274..772	CDD:440319	164/537 (31%)
		DEXHc_RAD54B	274..508	CDD:350824	79/265 (30%)
		DEGH box	409..412		2/2 (100%)