Protein Alignment kis and chd7

DIOPT Version :9

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: XP_697956.4
• Gene: chd7 / 569471
• ZFINID: ZDB-GENE-070912-179
• Length: 3140
• Species: Danio rerio
• Alignment Length: 4673
• Identity: 1294/4673 - (27%)
• Similarity: 1792/4673 - (38%)
• Gaps: 1799/4673 - (38%)

  Fly   511 GLPPMDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLA--ALQQQ-----------QAQQ 562
            ||....||.      |...|.| ||...:||.:|....:.||:  |:..|           |.:|
Zfish    23 GLGDCGYPQ------GQTNPMS-QQMPHEHQGYGQLPPSLHLSSPAVPGQAKLGHHFDPFNQYEQ 80

  Fly   563 QQQQVQQQQ------------QAPPQQQQQAAMLQA--QQQHH----------QQQLSMYGQPMG 603
            .:.....||            .:.|..:...|...|  ...||          .|.....|...|
Zfish    81 PKMHPMDQQGGRMMGNGPVNGMSSPHSRYHGAQAGAGGAAGHHVYPGAQGDGRSQSFPDSGNTWG 145

  Fly   604 QQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQ-LQHSINDIVGGGNSSGATGGAQNQ 667
            .||....:|..||...|||        |...||......| ..|.:...:|.|:.  |..| .||
Zfish   146 AQPMQVPEQTRPPFQQQPP--------QASSHQHGPAGPQGHAHQMGPFIGRGDY--AIQG-HNQ 199

  Fly   668 HQQQPQLAAMSSPLHQQ----------------NLPNMHHLIQPTMETTQPTQQ---------QQ 707
            .|..|::......|.|:                :.|.:.||.||:.:..||.||         ..
Zfish   200 TQTPPRMNHFPQGLPQEANHFLGHVGMTQNPGMSGPPIRHLAQPSQQHQQPNQQFLHRPGQGPVH 264

  Fly   708 QTSQQQQQPQQPQATLTSPHHQQMQHQSPI----HQQQQSPHHQQHLPSYN-QSQQQFDPFANIL 767
            ..|.....||.||    ||..||.|.|..:    ||......|.|.:||.. .|..|:.|:::..
Zfish   265 PDSVASHNPQFPQ----SPSRQQQQQQQVMGGRPHQNMGFNMHNQQVPSNTVNSSGQYPPYSSYG 325

  Fly   768 GDNQPAASQQTMSP---------AHVSSPV------PAQMQQQQHQT---QQQPSQQVPQSQQQQ 814
            ..||..|:...|||         ::.::||      ||....|::.|   ||.|..|.|....|.
Zfish   326 NLNQGLANTSGMSPNLSLTTSSNSNPNAPVTQVQRYPAPAGPQRYPTPGGQQGPLHQQPIHVNQI 390

  Fly   815 VSQPQQQTQQQQPSTP--SHHLSSILNETANSNDSST----LAVAA-----NDSNNSSSNSSTNS 868
            .:||....|.|..:.|  ..||......:.:|..|.:    ||..|     ......|:..:|:
Zfish   391 NTQPMHPAQNQATAQPKLQQHLPPPPQGSYSSPPSMSPMRNLATPAGTPPPQQVRPPSAGLATD- 454

  Fly   869 IVNNQPTSVHDS-----NSQSSINSSSNNQ----QQLLMDNTNSHGGNSESAQNAGVDVGLFDNN 924
             |...|...|.|     ::|......:..|    |||...:|:.|...::...
Zfish   455 -VGGYPGVPHQSQGPMAHAQRGAGPMNAAQPLPHQQLPSHSTHPHPPTTQMYA------------ 506

  Fly   925 SMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSV 989
            ::|.|..|.||...::.:...                |.:|..|              |||:
Zfish   507 ALSPNHRATAAQGRSSTTPGG----------------NHTEPPG--------------PQDQ--- 538

  Fly   990 SKTQDITLSTELPTIQDDLQ--EKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPG 1052
                      .|...|...|  :||....:|.||.|         :..|.::
Zfish   539 ----------RLHAQQAQCQQLQKPPLPFQQQQLQQ---------VHTPPSI------------- 571

  Fly  1053 VAPPADPIIPV---TQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMMPPYGGAPGMYPPYPM 1114
              ||:...:..   :.||.|                  ||....|..|  ||....|      .|
Zfish   572 --PPSQTHLAAHHQSSPPSQ------------------QAWAPTHQSP--PPMQKVP------HM 608

  Fly  1115 LHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPM 1179
            ||.                ||...|:                              ::..:..|.
Zfish   609 LHS----------------PPDPSLE------------------------------IITSSKTPA 627

  Fly  1180 YGP---PGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNVAM 1241
            .||   |.|..|.|:..|                   .||:.||.:||:|.:.|:..:||
Zfish   628 MGPNLQPANCDLQQKESE-------------------LKPKKKKKKKAKVSEGQECNNIS----- 668

  Fly  1242 GAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKK 1306
                                                ||..|:::..::..:.|.|..:...:||.
Zfish   669 ------------------------------------SEAGGEVTALMNEGDSLITPVEKPAEKKS 697

  Fly  1307 PRKP--RTPKDPNKPPRDRTPKA-KKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGE 1368
            .:||  :.||:|.:|...:|||. |.||:|.:|...:...|..|
Zfish   698 KKKPKEKEPKEPKEPKTPKTPKTPKTPKEPKEPKEKKVKTATPK--------------------- 741

  Fly  1369 GSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDS 1433
                       ||:                            ||.|
Zfish   742 -----------PKS----------------------------SKKP------------------- 748

  Fly  1434 VPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGED 1498
                                   |.:.::||.|.|.:|.         .||:....:..:
Zfish   749 -----------------------SAKKSDSESGNSTKKE---------AKRKREPSVTSD----- 776

  Fly  1499 DTLDRTPPPSPPPDSEMDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANAS 1563
              :::|||.||..:.:....||||||..:||:|.:|:..|.|||::....|.|    |.|:.:
Zfish   777 --VEKTPPQSPEEEDDDGVQKRRSSRQVKRKRYTEDLEFRISDDDDGDDSAGP----KSPTTS-- 833

  Fly  1564 NSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAM 1628
                                       |:..||
Zfish   834 ---------------------------EQQELP-------------------------------- 839

  Fly  1629 SSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDE 1693
                        |.:..||:.::.|||||:||
Zfish   840 ------------DAEGPVVEKIMGMRMGKKEL--------------------------------- 859

  Fly  1694 KFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESK 1758
                                                                             
Zfish   860 ----------------------------------------------------------------- 859

  Fly  1759 PEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKST 1823
                                                                             
Zfish   860 ----------------------------------------------------------------- 859

  Fly  1824 DDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRN 1888
                                      ..|||                      |:|||::||::.
Zfish   860 --------------------------ASGEE----------------------IEVEEFYVKFKG 876

  Fly  1889 FSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTD 1953
            ||||||.|...|||.| |:|:..||:||:.||:....:.| ::|||||.|:.|||||||:|..||
Zfish   877 FSYLHCRWADIEELEK-DKRIQQKIKRFRAKQALSTFVTE-MDDEPFNPDYVEVDRVLDVSESTD 939

  Fly  1954 ETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLE 2018
            | :||....|||||.||||||.||||:.|:|..|||::.|.  :.:..:.|..:||....|:|.|
Zfish   940 E-NGELVTLYLVKWCSLPYEDSTWELKADIDQVKIEEFERV--MAREPQLKRVERPPTSDWQKSE 1001

  Fly  2019 KTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVI 2083
            .:..||..|:||.|||||:|||.|:||||.||||||||||||||||:||::.:|..||.||||||
Zfish  1002 SSREYKNANALREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVI 1066

  Fly  2084 APLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMI 2148
            |||||||||:|||..||::||||||||..|::.||.||.||:...|:::|...||:.:|||||||
Zfish  1067 APLSTIPNWEREFRTWTELNVVVYHGSQASRKTIQAYEMYYRDTQGRIIKGAYKFHAVITTFEMI 1131

  Fly  2149 VTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLE 2213
            :||..:|:...||..:||||||||||||||||||:.:::||:|||:||||||.:.||||||||||
Zfish  1132 LTDCPELRNVPWRCVIIDEAHRLKNRNCKLLEGLKMMDMEHKVLLTGTPLQNTVEELFSLLNFLE 1196

  Fly  2214 PSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKY 2278
            |.:|.|:..||.|||.|:|||:|.|||.:||||||||||:||||:|||||||||||||||:||||
Zfish  1197 PDRFPSESTFMQEFGDLKTEEQVQKLQGILKPMMLRRLKEDVEKNLAPKEETIIEVELTNVQKKY 1261

  Fly  2279 YRGILEQNFSFLKK--------GTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHG 2335
            ||.|||:||:||.|        |...:|:|||:||||||||||.||||:|||||:|..:|:..|.
Zfish  1262 YRAILEKNFAFLSKSGAGGGSGGGGGSNVPNLLNTMMELRKCCNHPYLINGAEEKIMEEFRETHP 1326

  Fly  2336 ED-PESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGR 2399
            .| ||.:.:.:|.:|||:||||||||||||.|||||||||||||||||||||:.|:||:||||||
Zfish  1327 LDQPEFHLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGR 1391

  Fly  2400 IRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIG 2464
            :||||||.||||:|:|.||||||||||:|||||||||||||.||:||||||||||||||||||||
Zfish  1392 VRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIG 1456

  Fly  2465 QRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAY 2529
            |.|.||||||:.||:||||||||||:||||||||||||:.:.:.....:|||||||||||:||||
Zfish  1457 QSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENAANGVQQLSKKEIEDLLRKGAY 1521

  Fly  2530 GAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTKW 2593
            ||:|::::.|.||||||||.||:||||.||:||| |||||:||||.::|||:||:::|||||.||
Zfish  1522 GALMEEEDEGSKFCEEDIDQILQRRTQTITIESEGKGSTFAKASFVSAGNRTDISLEDPDFWQKW 1586

  Fly  2594 AKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG---HEDVMELNSEESSNENSDEEGGIGLRSR 2655
            |||.::|.||.  :...:||:..||.|.|.:.|.   .:|:||.:..||.:|:..      ::..
Zfish  1587 AKKAELDLDAI--NGRNNLVIDTPRVRKQTRHYSSMKEDDLMEYSELESDSEDKP------IQKP 1643

  Fly  2656 RRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLEL 2720
            ||.:.|.:                             .:.:||||:|||.||.:|||||.::|..
Zfish  1644 RRPQDRTQ-----------------------------GYPRSECFRVEKNLLVYGWGRWGDILSH 1679

  Fly  2721 GQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPR 2785
            |:|||..|:.|||...|.:|.|||..|:|||.||.||||||||||||:.:.:: :||||...|||
Zfish  1680 GRFKRPLRERDVETICRALLAYCLLHYRGDENIKGFIWDLITPTEDGQSRTLT-NHSGLSAPVPR 1743

  Fly  2786 GRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPN 2850
            ||.|.|..........|.....:..|
Zfish  1744 GRKGKKGKLPVAQTRMPQADWLADCN--------------------------------------- 1769

  Fly  2851 HWSKKEKYDADAYL-EGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPI-R 2913
                     .|..| |.:||:||..|.||||||||||||::.|||||...:|.:.|..|||.| .
Zfish  1770 ---------PDLLLQEDSYKRHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGTDSSELDIWI 1825

  Fly  2914 PPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPI 2978
            |.|....||:.||: :..|||||:|.:|||.|.|..|||||.|||:..||            :|
Zfish  1826 PQPFHADVPTDWWD-LDADKSLLIGVFKHGYEKYNSMRADPTLCFLERVG------------MP- 1876

  Fly  2979 NEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTE 3043
             :..|.:....|.::..||..            |:.:|....|.|
Zfish  1877 -DAKAIAAEQRGADMMADGVE------------GEEEDPEYKPLR-------------------- 1908

  Fly  3044 SENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPA 3108
                      .|:|        .|||               ..|:.|..:.||
Zfish  1909 ----------MSFK--------DDLD---------------DFTNSPLDDNND------------ 1928

  Fly  3109 DSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTE 3173
                              |..||                 ||:||.:
Zfish  1929 ------------------GMDGE-----------------TGEAPKL------------------ 1940

  Fly  3174 SCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTV 3238
                                       ..:.|..|
Zfish  1941 ---------------------------GENGKPGN------------------------------ 1948

  Fly  3239 AAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSM 3303
                   ..||....|..||||:||||||.:|:|:|:.:..||                |..:..
Zfish  1949 -------LYWPPASALTARLRRLITAYQRTHKREQLRQEAMAK----------------PDRRRR 1990

  Fly  3304 QMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGA 3368
            :                       .|.....|.::|.:.....|.|..:.||:....|.
Zfish  1991 R-----------------------PRDDILAMVTEGGAYVPDGAVAFMADGGAFMAKGS------ 2026

  Fly  3369 GVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQ 3433
               |.:|.:|.:              ||:     .|.|.                 |||.
Zfish  2027 ---PFIPDSAAL--------------LAD-----SAAYF-----------------KERR----- 2047

  Fly  3434 LIPKKWNRREEYEFLRVLTGYGV--DLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDY 3496
               ::|.||||.:|.||::.:||  |:|           ....||::|:..|.|::|:||:|..|
Zfish  2048 ---QRWTRREEADFYRVVSTFGVVYDVH-----------RQCFDWSQFRAFARLDKKTDESLEKY 2098

  Fly  3497 YKVFVAMCKRQAGLKLSESERGLEG---IIEEIEKEHAKLILDRLEVLAKLRE-VARNPMLEERL 3557
            |..|||||||...:.| :||..|..   ||:.|.:|.|...|.|:|:|.::|| |..:|:|||||
Zfish  2099 YCSFVAMCKRVCRMPL-KSETELPDPTIIIDPITEERASRTLYRIELLRRIREQVLPHPLLEERL 2162

  Fly  3558 KLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTI 3622
            .||..:.|.|.||||||||::|:....|||:.|::..|.|||..||.|:.::|.:
Zfish  2163 SLCQPSPDLPAWWEPGRHDRDLLRGAAKHGVSRTDYHILNDPELSFLEAYRKFTQ---------- 2217

  Fly  3623 KLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVT- 3686
                   .|..:|.....|..|                                       |:|
Zfish  2218 -------GKGVELPVIVSDPLT---------------------------------------PLTL 2236

  Fly  3687 PIKEEIKSEESP------EKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKD 3745
            |..||:|.|:..      |.....|..|:|:.......::|.:||.|
Zfish  2237 PKDEEVKEEQGDVTLPKVENGSIEDVKEEKSEALSPKKEVKNEEDEN------------------ 2283

  Fly  3746 KSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKC--SDAEDKKFSEEKPSSPAVPDGK 3808
                 .|.|:.|   |.|:||||||..|.|  .|....:.|  ....:||..:::|:. .:|..:
Zfish  2284 -----GLGPKQE---PKEEKMEVEEKDVTE--FKTDVEQVCPVDGMVEKKPMDQEPTD-TLPSSE 2337

  Fly  3809 VSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIES 3873
                  |:.|.:.:|..:|:..|.||..||:                 ||:.:|.:|.|||| ::
Zfish  2338 ------DKNAQDEKELPTGNKLSTEKASEDE-----------------EEKMDEDDKSEKSS-QA 2378

  Fly  3874 EPSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFP 3938
            |....||          :|:                     ..|:..|.....:.:..|.:..|
Zfish  2379 EVGALSE----------RKN---------------------FDEESNASLSTARDETNETRDCF- 2411

  Fly  3939 DLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSK----------- 3992
            .::.::| :..|...|:.....    |.||..:..|:.:|...|..|.||.:.:
Zfish  2412 SVDDVEP-SASQMFSERSLFSF----WPKDRVMINRMDNICEAVMKGKWPSNRRQFFDFPGLLPG 2471

  Fly  3993 YSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAAS 4057
            ||:.||                 .|.|:|||..                ..|.:.|.:.|.|...
Zfish  2472 YSSMAT-----------------ESPLQRRSLG----------------DLSLVGQTSYSGSEDL 2503

  Fly  4058 TSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAG 4122
            |.|  |||.:.           ||.|
Zfish  2504 TMS--PQVNKD-----------DALS--------------------------------------- 2516

  Fly  4123 GVSGLSVPSAGSGVGKKRKRHIAIDVETER-AKLHALLNSSTMAPKDWESEIANMEALSGSSGRG 4186
                ||||.      ::|:|...|::|.|| ||...|:..              :..|..|...|
Zfish  2517 ----LSVPR------QRRRRRRKIEIEAERAAKRRNLMEM--------------VAQLRESHAEG 2557

  Fly  4187 RGGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLK 4251
            :......:..:       |:..|..|:..|           |.:|.:...|.:.:      |:|:
Zfish  2558 QAQAIDLTKAL-------HSVSSSSSASAF-----------PGAMASSATLKAQM------ELLQ 2598

  Fly  4252 SASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKE 4316
            ..:||                            ....|.|.||..|....|:          |:.
Zfish  2599 PGASS----------------------------RPRANGSLLDTELPNRRKR----------GRR 2625

  Fly  4317 KKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTT 4381
            |..:.|:.:.:|                 :|:.|:             |:......|.|
Zfish  2626 KNVEGLELLFMG-----------------NKRGQL-------------SAELSDGTKAF------ 2654

  Fly  4382 VPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLAQ--TMATDPQT 4444
            |.|:           |..:..:....|.|.||.........|.|:|| |...|.|  |...|...
Zfish  2655 VDGR-----------THLAMPSPAQKASGEGLDEGSLQGEDGSSTKD-LREWLRQHPTYTMDMPG 2707

  Fly  4445 FLKQQQKMM--QFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLS 4507
            ::.:.:.::  ||..|.|:                  :....:|:.:.:|
Zfish  2708 YVPKNEDLLLSQFAKPKQK------------------RHRCRNPNKIDIN--------------- 2739

  Fly  4508 IDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEE 4572
                                                                       .|||||
Zfish  2740 -----------------------------------------------------------TLTGEE 2745

  Fly  4573 PVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPR-------PASM 4630
            .|||:|.:.|:::||..||.:|.|.:||.|||.|.:.|.|.:.::.....|...       |...
Zfish  2746 RVPVVNIRNGRKMGGAMAPPMKDLPRWLVENPEYAIAPDWTDIVKQSGFLPESMFDRLLTGPVVR 2810

  Fly  4631 ESGYGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAA 4695
            |.|     |:..|.||.:.::         :.::|||:.|               ||:||
Zfish  2811 EEG-----VRRRGRRPKAEIA---------KATAAAQAAA---------------AAAAA----- 2841

  Fly  4696 LQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFA 4760
               .:.:|:||.|:..|                         ||.| .:.::.||.||.::.|.|
Zfish  2842 ---ATTSGVNPLLMNGL-------------------------FGSM-DLTSLQGLQNLQSLQLAA 2877

  Fly  4761 SLAG----MGGLGNLAGMDTQSLAALMAAAGPTLGGLTG-----------------ASGGAGSGK 4804
            .|.|    :||     |.|.:..||::....|.:|||..                 |:.|| |..
Zfish  2878 GLMGFPTALGG-----GADAKHAAAMLPLMLPGMGGLPNMFSLGSLFGGNLAAAATATNGA-SST 2936

  Fly  4805 SQAQSQSSATSSSSSASK-KKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAG 4868
            .||:|:.::...:...:| :..:::::||:..:..:.   ||...|..|:....|||:|:.::.|
Zfish  2937 EQAESEENSKPKTDEETKGEGDEKEEKQAEKSSETVE---SADATGDAAALNAAAAAAAAGMSTG 2998

  Fly  4869 F----PFLFPN--PSLLYPPMGLGGLNPYSLGSSGL-GSAYDQLAQQYNLLNGA----------- 4915
            .    |||...  |.|.||.|.|    |.|||...: |.....||...:.::||
Zfish  2999 TLAFNPFLLSTMAPGLFYPSMFL----PPSLGGLAIPGFPQASLADLQSAVSGALGATGEDKESD 3059

  Fly  4916 ---------TSSASNTSSTQSKSHQSQSKSSQSRNTTASA--NSAASLMNAMASMGGG 4962
                     .:|.::..:..:....|.|:.||::...:|.  :..|.....|.||.||
Zfish  3060 KGPRTNQDPNASVADVETADNTLEDSDSEESQNKTADSSVLDDDLAGPAEEMDSMEGG 3117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	BASP1	1554..1786	CDD:283191	15/231 (6%)
		HepA	1676..2527	CDD:223627	439/859 (51%)
		SDA1	<1693..>1854	CDD:283052	1/160 (1%)
		CHROMO	<1879..1919	CDD:237991	22/39 (56%)
		Chromo	1941..1996	CDD:278797	34/54 (63%)
		DEXDc	2048..2197	CDD:238005	96/148 (65%)
		Helicase_C	2350..2464	CDD:278689	99/113 (88%)
		RR_TM4-6	3728..>3877	CDD:283990	37/150 (25%)
		BRK	4569..4613	CDD:197800	22/43 (51%)
chd7	XP_697956.4	Pro-rich	322..491	CDD:291893	40/170 (24%)
		CHROMO	845..906	CDD:237991	35/272 (13%)
		Chromo	927..978	CDD:278797	33/51 (65%)
		SNF2_N	1015..1310	CDD:278600	201/294 (68%)
		DEXDc	1031..1180	CDD:238005	96/148 (65%)
		Helicase_C	1342..1456	CDD:278689	99/113 (88%)
		BRK	2742..2786	CDD:197800	22/43 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	594	1.000	Domainoid score	I195
eggNOG	1	0.900	-	-		E2759_KOG0384
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1569	1.000	Inparanoid score	I83
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001075
OrthoInspector	1	1.000	-	-		otm24668
orthoMCL	1	0.900	-	-		OOG6_100621
Panther	1	1.100	-	-	LDO	PTHR45623
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3575
SonicParanoid	1	1.000	-	-		X648
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.850