|
Fly 813 QQVSQPQQQTQQQQPSTP--------SHHLSSILNETANSNDSSTLAVAANDS--------NNSS 861
|||:..|:.:..:.||.. .:::|..::..::..|......|...: |...
Mouse 175 QQVNHFQKDSIYRHPSLKVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC 239
Fly 862 SNSSTNSIVNNQPTSVHDSNSQ---------------SSINSSSNNQQQLLMDNTNSHGGNSESA 911
......::...:.:::.|.|:| ::.||...|.:|||..|......:||..
Mouse 240 KKCILRNLGRKELSTIMDENNQWYCYICQPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKT 304
Fly 912 QNAGVDVGLFDNNSMSSN------------SAAVAAVASNAA--------SAAAALLD--SNSQS 954
.........|.....||: |.:|::..|::| .....|:: ||..|
Mouse 305 SKVCDQTSKFSPKKSSSSCNGEEKKLEESCSGSVSSTYSHSALSVPKEMIKKTTKLIETTSNMNS 369
Fly 955 SNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDI---------TLSTELPTIQDDLQE 1010
|..:|.|..::...: .:...|.|.::..|...|| .|::|:..:.|..:|
Mouse 370 SYIKFLKQAADNSEM-------TSAMKLCQLKSFKSVLDDIKKAHLALEEDLNSEIQALDDVHKE 427
Fly 1011 KPTAEME------QTQLGQSLGDLSKSL-------LEEPKTV-----EE-------SGEDKSQSA 1050
|.|.::: :|:||: |:.|.|. |:...:| || |||.|...
Mouse 428 KNTKDLKSTDAKSETKLGK--GEKSYSTEKREFLKLDARSSVKAIDGEEQRAHKSTSGEHKGSG- 489
Fly 1051 PGVAPPADPIIPVTQPPQQQMPPIGMP-------MHPIAPGYEAQA----QGQGHMPPMMPPYGG 1104
........|...|....|..:.:| ...:....|.|: ||.|:. |.
Mouse 490 ---RKDGSQYEPTNTPEDLDMDIVSVPSSVPEDIFDSLESAMEVQSSADYQGDGNS-------GT 544
Fly 1105 APGMYPPYPMLH----------QQEIAALQQQIQELYC-MPP---------GHELQH--QDK--- 1144
.|.:......|: :.::.|..: :||:. :.| |.:.|. |:|
Mouse 545 EPELESSSVKLNVSSKDSRGNIKSKVTAKVR--KELFVKLTPVSLSNSPIKGVDCQEVSQEKNGR 607
Fly 1145 ----LMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRG 1205
:.|..|:.. .:.|::|. ..||..: |.:..:..||:|.:|..|.
Mouse 608 KSSGVARSSEKCR--PREEISDH---------ENNVTIL-------LEDSDLRRSPRVKTTPLRR 654
Fly 1206 RGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNV----AMGAANAVS------SIPTTQLPVSED 1260
:.:| .|.....::...|..::...:||.: ...:|:..: .:|..:.||..|
Mouse 655 QTES-----NPAMSNSDEESNGTMKEKQKMSGPIRKKDKRNSADCATDNPKPHKVPKAKQPVIGD 714
Fly 1261 CVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELD------TSTDGSGKKKKPRKPRTPK---DP 1316
|.:....::.:|:.:..||..|......||.. |..|.:||:| ||..|.. |.
Mouse 715 ---QNSDSDEMLAVLKEASQMGHSSSSDTDINEPQMNHKGKTGKDDNGKRK--RKNSTSGSDFDT 774
Fly 1317 NKPPRDRTPKAKKPKDPNDPNSTETPAAVKK------RAGASKR----RKQYGEDGAEQTGEGSE 1371
.|.....|....|.|..|...|:...:.::: |.||::: :|: ||.:|...:|.:
Mouse 775 KKGKSTETSIISKKKRQNYSESSNYDSELEREIKTMSRIGAARKSVPEKKE--EDSSEDEKQGKK 837
Fly 1372 VEDN-----KPLVPKAGSAD--GEAETTSGGT-GVDGESPDYDDIPVSKIPRG------------ 1416
|.|| .....:..||| |:.|...||: .:.|.| :.|:..|
Mouse 838 VVDNGGHERAKTTQEGSSADDTGDTEGRQGGSCSIAGGS-------IEKVRSGVEFREMLCKPGV 895
Fly 1417 SNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGS------ARKNRGS 1475
|::..::....:|.|:|..| ...|:...|....|||::...:.|.| .:|.:..
Mouse 896 SSDGAEKPSVKEENVNSPED------KRVSKTKEKTKHLRSRQSRKGKGGSSDGTDRFPKKEQSD 954
Fly 1476 LSAKALKKRR-----NRGRIVPESDGE-------------------------------------- 1497
.|::..||:. .:|:..|:..||
Mouse 955 ESSEGEKKQSRQRPGTKGKKAPDLKGETLKREQEWDSSSDGTERLPEEEEIGPFSKGIKQSKTDT 1019
Fly 1498 ---------------------DDTLDRTPPPSPPPDSEMDSNKRRSSRNTQRKKYIDDVMLRF-- 1539
.|::|:.|......||..| .|.|:..:.:.|| ||
Mouse 1020 AGGEKKGKKWKDKSCEKKEELSDSVDKLPGKGDSCDSSED-KKTRNRVSLREKK-------RFSL 1076
Fly 1540 -------------SDDENSL-------LVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEG-- 1582
||.|.|| ....|.:.|.:...|:|:.....:|:.....|.|||
Mouse 1077 PAKSPGKRPECSSSDTEKSLKGQCCDSTEKRPKRIDLRERRNSSSKRNTKEVKSASSSSDAEGSS 1141
Fly 1583 -----------DAAQEVG---EEKSN--LPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSK 1631
.|.::.| |:|.| ....:..|::.:||:|.:.:.::..:.:.::.....|
Mouse 1142 EDNKKQKKQRTSAKKKTGNTKEKKRNSLRATPKRKQVDITSSSSDIGDDDQNSAGEESSDEQKIK 1206
Fly 1632 P---NYVY-------INTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPK------QDEEKSE 1680
| |.|. .::||| |:.......:.|...:..||.: .:|.|:.
Mouse 1207 PVTENLVLPSHTGFCQSSGDE---------ALSKSVPATVDDDDDDNDPENRIAKKMLLEEIKAN 1262
Fly 1681 L----DEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAM-EVDSKEESEPDDSKK------- 1733
| |.::.|:|:|..|.:...:|::...|..|.:.|..|: :|:|:.:|:.::|||
Mouse 1263 LSSDEDGSSDDEPDGGGKKRIGKQSEESPADDGELRREQLAVNQVNSESDSDSEESKKPRYRHRL 1327
Fly 1734 ----------------------------------SDEDNKDKDKME--VDDEVGKSDKESKPEEQ 1762
|.||::|.|..| |.:||.:|:.|.:|..:
Mouse 1328 LRHKLTLSDGESGEEKPTKPKEHKEAKGRNRRKVSSEDSEDTDFQESGVSEEVSESEDEQRPRTR 1392
Fly 1763 S-ETVKTEENSKA-----------IEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKA 1815
| :..:.|||.:: ::||.||. ...|::| :|.|.||:..:|:....:.
Mouse 1393 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSE--NKSHSEE-----DKKEGDEEDEEDEDEDEED 1450
Fly 1816 EGSDEKS------------------TDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDE 1862
|..|.|| |:..|..:...|:.|...|.|.|:|::: |.::.|:..
Mouse 1451 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLR---EVIEIEDAS 1512
Fly 1863 KTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIF 1927
.|:..:..| :.:|..| .|:|.|::..|.:..|::..|
Mouse 1513 PTKCPITTK---LVLDENE---------------ETKEPLVQVHRNMVIKLKPHQ---------- 1549
Fly 1928 ENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYL 1992
||.|..| | ||..|..|
Mouse 1550 --------------VDGVQFM------------------W------DCCCESVE----------- 1565
Fly 1993 RFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMG 2057
|:||.| |: .||||..||
Mouse 1566 -----------KTKKSP----------------GS---------------------GCILAHCMG 1582
Fly 2058 LGKTIQSLTFVHSV-----YEYGIRGPFLVIAPLSTIPNWQREFEGW----TDMNVVVYHGSVTS 2113
||||:|.::|:|:| .::... ||:.||:|..||..|||.| .|...:......|.
Mouse 1583 LGKTLQVVSFLHTVLLCDKLDFSTA---LVVCPLNTALNWMNEFEKWQEGLNDNEKLEVSELATV 1644
Fly 2114 KQ-----------------MIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWR 2161
|: ||..||.|.....|: .:|...|...|...:.| ...::.
Mouse 1645 KRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGR----NVKSRKLKDIFNKALVD----PGPDFV 1701
Fly 2162 LCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSE 2226
:| ||.|.|||....:.:.:..:....|::|:|||||||:.|...::||::.:...|.:||.:.
Mouse 1702 VC--DEGHILKNEASAVSKAMNSIKSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNR 1764
Fly 2227 F----------GSLRTEEEVNKLQA-----LLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQK 2276
| .|...:..|.|.:| :|...:.|:....:.|.|.||.|.::.|.:|.||.
Mouse 1765 FINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTAIQC 1829
Fly 2277 KYYRGILEQ-----NFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLL----------------- 2319
|.|:..|:. |.:...:|...| .|......|.:...||:.|
Mouse 1830 KLYQYYLDHLTGVGNSTEGGRGKAGA---KLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDS 1891
Fly 2320 -------------------------------------NGAEEQIQ----YDFKSQHGED------ 2337
:|::..:: ::.:|:.|.|
Mouse 1892 MDEFIASDSDETSKSLSSDEKKKPKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGDGNVDDT 1956
Fly 2338 --------------------PES----YYKNLILS--------AGKMVLIDKLLPKLKANGHRVL 2370
|.| :||:.:.. :|||||:.::|...:..|.:||
Mouse 1957 GNNPSVSLKLDESKTTSTSNPSSPAPDWYKDFVTDTDAEVLEHSGKMVLLFEILRMAEEIGDKVL 2021
Fly 2371 IFSQMVRCLDILEDY---------------LVY-------RKYPFERIDGRIRGNLRQEAIDRYS 2413
:|||.:..||::||: |:| |...:.|:||......|::..:.::
Mouse 2022 VFSQSLISLDLIEDFLELASREKTEDKEKPLIYKGEGKWIRNIDYYRLDGSTNAQSRKKWAEEFN 2086
Fly 2414 KPGSDR-FVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCR 2477
...:.| .:|::.||||.|||||.||:.|||:|:.|||..|:|:..|.:|.||.|.|.:||.|.:
Mouse 2087 DETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQ 2151
Fly 2478 NTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKF 2542
.|.|.:::|:...| ||::.: |:|.......|
Mouse 2152 GTMEDKIYDRQVTK--------QSLSFR--------------------------VVDQQQVERHF 2182
Fly 2543 CEEDIDSILKRRTQVITMESEKGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERD 2607
...:: |::.|.|.: .:|||:...|..:...:.|
Mouse 2183 TMNEL-------TELYTFEPD-------------------LLDDPNSEKKKKRDTPMLP------ 2215
Fly 2608 ETEDLVLSEPRRRTQIKR------YGHEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRARE 2666
:|.:|:| ..||.: :.|:.:::...|| |.::|| |:....:...|
Mouse 2216 --KDTILAE---LLQIHKEHIVGYHEHDSLLDHKEEE---ELTEEE--------RKAAWAEYEAE 2264
Fly 2667 KKG--------------------NDEYIPRERDALAALGLEEIQ 2690
||| ...|||....||:|:..::::
Mouse 2265 KKGLTMRFNIPTGTNLPPVTFTSQTPYIPFNLGALSAMSNQQLE 2308
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