Protein Alignment kis and chd-7

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_491426.2
• Gene: chd-7 / 172079
• WormBaseID: WBGene00007053
• Length: 2967
• Species: Caenorhabditis elegans
• Alignment Length: 4885
• Identity: 1189/4885 - (24%)
• Similarity: 1715/4885 - (35%)
• Gaps: 2069/4885 - (42%)

  Fly   159 YGAQQSMMAGY---GSLAPQQQQQQQPPTPQQ-----QQQAQQVQQQAQQQQQQQQQQSQQQARL 215
            |..|.|.||.|   |...|||.||.|...||:     ....:|.||..|....|||.|.|..|..
 Worm     7 YVPQMSQMADYTMMGGPPPQQSQQSQQGVPQRYPGQPMNPYEQQQQHHQMMMMQQQHQMQHMAPP 71

  Fly   216 PQHYPQAPGQHPLYP--------------GVGAPTVQAGQPPTPQAYAHSPYGSPMQHQPSRGAP 266
            ||..|..|.|.|  |              ...|....|.....|.|...:...:||..|.
 Worm    72 PQQVPPQPAQPP--PAKKARGKSKKAQAEAAAAAAAAAAAQMDPMASMAAMSNNPMMRQG----- 129

  Fly   267 QHVGYGHTGLDQASAYGQHVPGGAPPGHHLSAQQQQAAQQLGAHQQQQLQSQQQQQAQQQQPHVS 331
               ||.    :|.:.|     ||.||.|:.|:                  :...||..:..|..:
 Worm   130 ---GYP----NQMAMY-----GGVPPPHYPSS------------------NGPSQQGYRPGPVTN 164

  Fly   332 -LMQQQQLPGAGLPPPHMGMPPSYGS-HHQQQQQQQQTQQQQQQSAPPYMSSSKHQQAAAQLNSS 394
             ...|.|.|    |||.  .|.:|.. :|||:.||||..|||.|..|.|.......||:......
 Worm   165 GPPPQGQYP----PPPQ--APQNYQQMYHQQRAQQQQAGQQQAQGPPGYGPYGYAPQASTGYPPP 223

  Fly   395 PQYRAPFPQLSPQMSPRPPTM----SPHPQMSPRP---VGVSPAKPPPPQQQQQQTQAQQPQQVV 452
            |..::|:   :||..| ||.|    .||.|....|   .|......|||.|||||..........
 Worm   224 PSQQSPY---APQAGP-PPQMRHQYPPHSQQQAPPGYWDGYQGYGGPPPSQQQQQQGGGPVTAPQ 284

  Fly   453 SNQPSQHSIQGMVGLPSPRPQPPTSGAGGAGA---KGPAPVAAPVNTLQALEQMVMPSQALGLPP 514
            |.|.:|....|.||         |:......|   |..|...|.:..|..::
 Worm   285 SMQMAQQEQWGRVG---------TNDLMNVIAQVEKSSAECKARIQQLYNMQ------------- 327

  Fly   515 MDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLAALQQQ--QAQQQQQQVQQQQQAPPQQ 577
                   |||     .|..:.||.||:          ||..|..  :..||.|.||.|||   ||
 Worm   328 -------RSA-----SADAEVQQLQHK----------LAQFQSDHYRYSQQLQHVQWQQQ---QQ 367

  Fly   578 QQQAAMLQAQQQ-------HHQQQLSMYGQPMGQQPQTAQQQVVPPVTSQPPVVAASQQQQQQQH 635
            |||||...|...       |||      |.|   .|.::|...:|...:..||..  .|...|.|
 Worm   368 QQQAAAAAAAAAAAASAGGHHQ------GPP---PPTSSQSNQIPSNPNSVPVHV--NQPGSQVH 421

  Fly   636 QQQSLNDQLQHSINDIVGG-GNSSGATGGAQNQHQQQPQLAAMSSPLHQQNLPNMHHLIQPTMET 699
            ........|....:|..|| |:.:.:|...::....:|..:...||:  .|.|      |..||.
 Worm   422 ITADKTRTLISVYHDGYGGAGSGASSTESKESIVPPEPTPSMQESPV--PNAP------QVKMEP 478

  Fly   700 TQPTQQQQQTSQQQQQPQQPQATLTSPHHQQMQHQSPIHQQQQSPHHQQHLPSYNQSQQQFDPFA 764
            .:|:..|||.:..:.....|.|.....|....|:|   .||||...|||::..|.|.||
 Worm   479 EKPSPYQQQYNGMENGSGNPYAQQQQQHPMYAQYQ---QQQQQHAQHQQNMSGYPQQQQ------ 534

  Fly   765 NILGDNQPAASQQTMSPAHVSSPVPAQMQQQQHQTQQQPSQQVPQSQQQQVSQPQQQTQQQQPST 829
                  ||....|...||    .||.|...|||.:|.|             :||.|| |||.||
 Worm   535 ------QPQHPHQHQQPA----SVPMQHHPQQHPSQHQ-------------TQPNQQ-QQQHPS- 574

  Fly   830 PSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQ 894
             .:.:.                                  |:..|.|:..  |||...|:..:|.
 Worm   575 -GYGIG----------------------------------VSTAPASMEP--SQSVDQSAPPSQA 602

  Fly   895 QLLMDNTNSHGGNSESAQNAGVDVGLFDNNSMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEF 959
            |:...:|.|   .|...|||..:...|.::| ......||..|..:.|.:..::..:||:.
 Worm   603 QIPATSTPS---TSSQQQNAYPEFPDFPSSS-GYQEPTVAPEAIPSPSVSDPIMPQSSQND---- 659

  Fly   960 EKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDITLSTELPTIQDDLQEKPTAEMEQTQLGQS 1024
            ::.|:..:...::|.|...|..:.:||.....:|: |:..|  .::|:::.|   |.:|:
 Worm   660 QELQAISDQQEILEDVPKEEPIIEEDEPKYEYSQE-TIPVE--ELKDEVEFK---EDQQS----- 713

  Fly  1025 LGDLSKSLLEEPKTVEE--SGEDKSQSAPGVAPPADPIIPVTQPPQQQMPPIGMPMHPIAPGYEA 1087
                :.:|||:...::.  ..|:.:::                                  ||.
 Worm   714 ----TSNLLEDDTGIDNFVKNEEGAEA----------------------------------GYS- 739

  Fly  1088 QAQGQGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERL 1152
                           .|.|
 Worm   740 ---------------NGTP---------------------------------------------- 743

  Fly  1153 NLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPR 1217
              |.|.|.||          ::|:..               |.||||...
 Worm   744 --LDQVEQND----------YENIEK---------------EEPQVSVDP--------------- 766

  Fly  1218 AKKGEKAQVGQQQDLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMG 1282
                |..:|..||:..|                 |.:.|:..            ||.:|
 Worm   767 ----EPVEVEAQQEPAD-----------------TEEYPIPS------------VGTIE------ 792

  Fly  1283 DLSQDVHSANELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKAKKPKDPNDPNSTETPAAVKK 1347
                                            :|.:.|.:...:..:|.|.:.|....||  ||
 Worm   793 --------------------------------EPAEEPAEEPVEEPEPMDDSSPVDQSTP--VK- 822

  Fly  1348 RAGASKRRKQYGED-----GAEQT-GEGSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYD 1406
                       .:|     |.|:| ||..||:|
 Worm   823 -----------ADDIENFAGVEETFGEEEEVQD-------------------------------- 844

  Fly  1407 DIPVSKIPRGSNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARK 1471
                        ||:.||.:...:.|.:.:...|..||.::
 Worm   845 ------------EDDDEASSAKSSKDDIKEEEDDDTSTITK------------------------ 873

  Fly  1472 NRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSPP--PDSEMDSNKRRSSR-------NTQ 1527
                                ..|:...:|.|....||.|  |.....|:|::|.|       .::
 Worm   874 --------------------DMSEAPSETNDGFTEPSTPATPLMGATSSKKKSYRRPAVVVAKSR 918

  Fly  1528 RKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNSNAGSDVEKTEP--QSGAEGDAAQEVGE 1590
            :||.:||     |||:           |..|.........|...:|.:|  ::|.||
 Worm   919 KKKSVDD-----SDDD-----------DFYPQRGRGKKKGGGGKKKADPTDEAGVEG-------- 959

  Fly  1591 EKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRM 1655
            .||:   ||..:......|.|                            .|.::|||:.:|.|||
 Worm   960 AKSD---DEDDEFLMKIDTPA----------------------------PDPNAMVVEKILNMRM 993

  Fly  1656 GKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEV 1720
            ||.|
 Worm   994 GKVE------------------------------------------------------------- 997

  Fly  1721 DSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLT 1785
                                                                             
 Worm   998 ----------------------------------------------------------------- 997

  Fly  1786 ADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEK-ERV 1849
               .|.|||     ||             ||||:|      |.||.:.||.|:..:..||. |.|
 Worm   998 ---KKVPET-----EV-------------AEGSEE------NGEEKSEEKVKKEPKENGENGESV 1035

  Fly  1850 KEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIR 1914
            ..||.|..|...|..|.:.|        :||::.:|::..||:||||:|..|||:.|:||.|||:
 Worm  1036 GNGESSKSKTESETNEIEEE--------EVEQFLIKWKGRSYVHCEWKTAAELLEIDKRVEAKIK 1092

  Fly  1915 RFQ-QKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWE 1978
            ||: :|.|..:.     :||.||.||..||||:|:....|   |:  :..|:|||||.||:.|||
 Worm  1093 RFKVKKMSSYIE-----DDEDFNSDFVIVDRVVDLITEDD---GQ--EFVLIKWKSLGYEEVTWE 1147

  Fly  1979 LEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFS 2043
            ..|.:..||:|.: |..::...::.:.|:||.||.|||:..:.|:|.|||||.||.||::||.:.
 Worm  1148 PIEMIPADKVELW-RERQVIDPAKIREKQRPEPEEWKKMSTSKVWKNGNSLREYQFEGVDWLLYC 1211

  Fly  2044 WYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYH 2108
            :||..|||||||||||||:|::||:..:|:|||.|||||:.|||||.||.||||.|||||.:|||
 Worm  1212 YYNAQNCILADEMGLGKTVQTITFLSRIYDYGIHGPFLVVVPLSTIQNWVREFETWTDMNAIVYH 1276

  Fly  2109 GSVTSKQMIQDYEYYY-KTESG--KVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHR 2170
            ||..:::::|.||.:| |...|  ...|..:|.:.||||||.:|:|...||...||:||||||||
 Worm  1277 GSAYAREVLQQYEVFYDKRHCGAKNWKKNFVKIDALITTFETVVSDVEFLKKIPWRVCVIDEAHR 1341

  Fly  2171 LKNRNCKLL-EGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEE 2234
            ||||||||| .||....:||||||:||||||||.|||||||||.|.||.:...|:.:|||.:|::
 Worm  1342 LKNRNCKLLVNGLLAFRMEHRVLLTGTPLQNNIDELFSLLNFLHPQQFDNSATFLEQFGSCQTDD 1406

  Fly  2235 EVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANI 2299
            :|.|||.:||||||||||:||||||.|||||||||:|:::|||:||.|||:|||.|.|||::
 Worm  1407 QVQKLQEILKPMMLRRLKEDVEKSLGPKEETIIEVQLSDMQKKFYRAILERNFSHLCKGTSA--- 1468

  Fly  2300 PNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHGE-DPESY-YKNLILSAGKMVLIDKLLPKL 2362
            |:|||.||||||||.||:|:|||||.|..||:..|.: |.|:. :|.||.::||:|||:||||||
 Worm  1469 PSLMNVMMELRKCCNHPFLINGAEEAIMNDFRLAHPDWDEETLAHKALIQASGKVVLIEKLLPKL 1533

  Fly  2363 KANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTK 2427
            :.:||:||||||||:.||:||::|:...||||||||.:||:|||.||||:||..||||||||||:
 Worm  1534 RKDGHKVLIFSQMVKVLDLLEEFLISMSYPFERIDGNVRGDLRQAAIDRFSKENSDRFVFLLCTR 1598

  Fly  2428 AGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKL 2492
            ||||||||||||||||:|||||||||||||||||||||:|:||:|||:..||||||||||||:||
 Worm  1599 AGGLGINLTAADTVIIFDSDWNPQNDLQAQARCHRIGQKKLVKVYRLITSNTYEREMFDKASLKL 1663

  Fly  2493 GLDKAVLQS---MNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRR 2554
            |||||||||   :..:|:      .||||::|:||||||||::||::|...||.||||::||:||
 Worm  1664 GLDKAVLQSTTALKAEGT------ALSKKDVEELLKKGAYGSIMDEENESSKFNEEDIETILQRR 1722

  Fly  2555 TQVITMES-EKGSTFSKASFAASGNR-SDITIDDPDFWTKWAKKVDIDPD-ACERDETEDLVLSE 2616
            ||.||:|: :|||.|:||:|.:|.|: .||.||||:||||||:|..:|.: |....:..:|::.|
 Worm  1723 TQTITLEAGQKGSLFAKATFNSSHNKGDDIDIDDPEFWTKWAEKAQVDVEKATATPDGRELIIEE 1787

  Fly  2617 PRRRTQIKRYGHEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRAREKKGNDE-------YI 2674
            ||:||  ||:      |.|.:|..::.|:|.|.   |.|...|||.|   ::||||       |.
 Worm  1788 PRKRT--KRF------EENKDEGDSDGSEESGN---RKRGAAEKRKR---RRGNDEDGDYSGSYR 1838

  Fly  2675 PRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDVDVEDCARII 2739
            |   |.||.           :|:|.|||||.|..:|||||:|:.:.|:.:..  :.|:|..:|.:
 Worm  1839 P---DELAT-----------SKAEYFKVEKVLAQYGWGRWAEIKKYGELEIS--EQDIEHMSRTL 1887

  Fly  2740 LLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAP 2804
            ||:|::.::||::|:.|:::||.|....|.||:
 Worm  1888 LLHCIREFRGDDRIRQFVFNLIRPQGIQENQKL-------------------------------- 1920

  Fly  2805 GSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAY-LEGAY 2868
            |:.|..|.|                                      |:...:::..:: |:.|:
 Worm  1921 GAGSMYNQG--------------------------------------WAGLPEFNPPSFALDSAF 1947

  Fly  2869 KKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKD-NTPISELPIRPPPTPDQVPSSWWNPICCD 2932
            ::|:.|||||:::::.||.:::..:|||....::| |...:::.:...||..:.....|:. .||
 Worm  1948 QRHVHRHANKLMVKIDMLKHLEIHLIGDERALVEDFNVKWTDIKLPEMPTISETFIEGWDS-DCD 2011

  Fly  2933 KSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPINEDDANSKHDDGDEVDDDG 2997
            |..|:|.::||.:.:..:|.|.||||
 Worm  2012 KCFLIGCWRHGLDNFDAIRVDENLCF--------------------------------------- 2037

  Fly  2998 TTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTESENDATTVSESSYKSEVLP 3062
                                                                             
 Worm  2038 ----------------------------------------------------------------- 2037

  Fly  3063 GKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAGKAQGTGVQTG 3127
                                                                             
 Worm  2038 ----------------------------------------------------------------- 2037

  Fly  3128 DAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTI 3192
                                         |:|:.|
 Worm  2038 -----------------------------AEKNLA------------------------------ 2043

  Fly  3193 TNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTR 3257
                                                                  :||...|...|
 Worm  2044 ------------------------------------------------------VWPGQTDFWLR 2054

  Fly  3258 LRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSA 3322
            .||::|:.|::.
 Worm  2055 FRRLLTSSQKSV----------------------------------------------------- 2066

  Fly  3323 QHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSIL 3387
             ||                                                 |.
 Worm  2067 -HD-------------------------------------------------PV----------- 2070

  Fly  3388 NTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLT 3452
                        .|||                                  .|.:|||.||:||:.
 Worm  2071 ------------YNKL----------------------------------NWTKREEQEFIRVVR 2089

  Fly  3453 GYGVDLHVSTPMASSNGSSLSPDWTKFKQMAH-LERKSDETLTDYYKVFVAMCKRQAG---LKLS 3513
            .|||..::        |...:.|||.||.::. ||:|:||...:.....:|||:|..|   ||..
 Worm  2090 SYGVKTNI--------GEGGNEDWTIFKTLSPILEKKTDEDCHEQLMCVLAMCQRAQGSNDLKPI 2146

  Fly  3514 ESERGLEGIIEEIEKEHAKLILDRLEVLAKLREVARNPMLEERLKLCTKNADTPDWWEPGRHDKE 3578
            :.:|.:.  |:.:....|..:::|:.::.|:..:.:. :.|..|:|| :....|..| ..:||||
 Worm  2147 DLKRAMS--IDPMPTRKAIKMMNRISLMRKVHTMVQT-LSELNLELC-ETTGMPSGW-CMQHDKE 2206

  Fly  3579 LITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAA 3643
            |:....:.||.:....:.|.|.|:      :.:|..|..:.|.:
 Worm  2207 LMEICDQCGLDQLAANVLNKPAFT------KIVRPSETTLLRRL--------------------- 2244

  Fly  3644 TEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLE 3708
                       .|..|::
 Worm  2245 -----------LEIVATI----------------------------------------------- 2251

  Fly  3709 DKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPV 3773
                   ||.|..|..|                           |..:.|
 Worm  2252 -------ESGKWCGVAD---------------------------VETVND--------------- 2267

  Fly  3774 AENGEKEGSPEKCSDAEDKKFSEEKPSSPAVPDGKVSEMEADEAAPNTEENCSGDSESPEKECED 3838
                         ||:||||                 :|.|..||
 Worm  2268 -------------SDSEDKK-----------------DMAAVAAA-------------------- 2282

  Fly  3839 KVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIESEPSEKSETVLEPEVAVPKKSTGDQDILDLV 3903
                       :..:.:.::|:::.::....:..|..|.|         |..|:...|.|
 Worm  2283 -----------QAQFLRLQQQQQQQQQAAAVAASSSASRK---------ASRKRPNNDND----- 2322

  Fly  3904 AGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVI------------QPATVKQQKLEKP 3956
                         .|.:|:::....|.....|.:..:..:            |..|..||:
 Worm  2323 -------------AKMRAMQQMLMGQGGSGAAEYASMIALMLMPQMMAASGGQNMTAAQQQ---- 2370

  Fly  3957 KLEMCMIRWFKDFALERRIAHIVA-CVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLE 4020
                         ||.:.:..::| .|:      ..:.:..:|.|||:...          ||.:
 Worm  2371 -------------ALNQMLTMLIAGAVQ------QQQQAQPSTSKGASSSQ----------SSAQ 2406

  Fly  4021 RRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSIN 4085
                        .:|..........:.|||::|||:::|:....|.|.:    ..|..|.|.|:|
 Worm  2407 ------------ANQAAQAQAAAVALAQVAAAASASTSSADAQAVAQQQ----QVLEALLAMSMN 2455

  Fly  4086 AAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVET 4150
            .|                        :|:|.||:|:.  :|.|.|||    .||.|
 Worm  2456 PA------------------------ALAALTGTSSS--TGTSTPSA----PKKSK--------- 2481

  Fly  4151 ERAKLHALLNSSTMAPKDWESEIANMEALSGSSGRGRGGNSSASSGMQPPPAHQHASLSRQSSGQ 4215
                         .||:        .|:.|.::......::.|::........|.|..::|::.|
 Worm  2482 -------------PAPQ--------KESTSSATAAAAAASAQAAALAAAQQQQQQAQQAQQAAQQ 2525

  Fly  4216 FSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAAL 4280
                 ..:.||           ...|..:.:.|:       ..:.:.|:...:..||.:.|
 Worm  2526 -----AQSAKT-----------QEELLILRLLEL-------AGVGMQELAKLNTMSKDARV---- 2563

  Fly  4281 SSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPS 4345
                                          |:|.|:.:.                      |||.
 Worm  2564 ------------------------------PMIHKQTRE----------------------SLPV 2576

  Fly  4346 SKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKS---KSGSSNSGSGTGGSSSASGGG 4407
            ||:|.|                     :..|:.|.:.|..|   ...:..||:|||..::.|...
 Worm  2577 SKRPPI---------------------RDLTVFVMSNPEWSIDIPLFNEMSGNGTGSGAAPSSKA 2620

  Fly  4408 AGGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQKMMQFLPPAQRKAYENMLAEME 4472
            |......|...:|:
 Worm  2621 ASSRPTPAATPLAV--------------------------------------------------- 2634

  Fly  4473 QAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQS 4537
                     :|..|...||.|..:..::|                 .....|...|.:.|.|.|.
 Worm  2635 ---------ATPKPSTPKVEKSSATPSAP-----------------ETPSASATCNIKIGESLQF 2673

  Fly  4538 SSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTE 4602
                                             ::.:.|.|::||:.|..:|.|:...|..||..
 Worm  2674 ---------------------------------DDMISVFNRKTGELLAASKWPKATELSAWLDA 2705

  Fly  4603 NPNYEVDPKWLEQMQNPMSTPSPRPASMESGYGSSAVKSH---GGR----------------PLS 4648
            ||:|.|                         :.:||:.:|   ||.                |.:
 Worm  2706 NPDYNV-------------------------HANSALFAHLSLGGAHSDRIGDATPAVTASVPST 2745

  Fly  4649 NLSSTSSSSHTQQQSSAA------QSQAGGNSGSSKKNSRQQTAA--SAALDQAALQFGSLAGLN 4705
            ...|||:|:...|..:.|      |:|...::.:|.| ||..|||  :||...||.|..::....
 Worm  2746 PTPSTSASAANAQLMALALAQQVQQAQQTPSTPTSSK-SRSATAAAQAAAAQAAASQQDAITKQQ 2809

  Fly  4706 PSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFG--GMPGMGNIPGLGNLNNMNLFASLAGMGGL 4768
            ..:|         ..:..|..:.....|.||.:|  |||.........:..|:   ||:|.|.
 Worm  2810 LEML---------QMQMMLQQYQQAAALQSMLYGGYGMPTTSTAASSSSTANV---ASMAAMA-- 2860

  Fly  4769 GNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQ 4833
                       ||..||:.||......||....|..:.|.:|:.:||..|::|:
 Worm  2861 -----------AAAQAASTPTTSKQASASTSTPSTSAVASAQTPSTSVPSTSSQ----------- 2903

  Fly  4834 NEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGL 4898
                  |||.:||:..||..      .:...|.|    |..||::|...|    |:..|: .:.|
 Worm  2904 ------AAAAAASSANSGED------INPLLLTA----LMQNPAILQSMM----LSDPSI-LAAL 2947

  Fly  4899 GSAYDQLAQQ 4908
            .:|..|..||
 Worm  2948 AAAQQQQQQQ 2957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830	84/337 (25%)
		Med15	<1056..>1265	CDD:312941	22/208 (11%)
		PRK12678	1319..>1500	CDD:237171	26/186 (14%)
		PTZ00121	<1419..1923	CDD:173412	102/516 (20%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	28/67 (42%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	25/57 (44%)
		PLN03142	2029..>2606	CDD:215601	377/588 (64%)
		PTZ00341	<3662..3887	CDD:173534	21/224 (9%)
		BRK	4568..4611	CDD:462196	14/42 (33%)
chd-7	NP_491426.2	Atrophin-1	<387..>666	CDD:460830	93/376 (25%)
		PRK12323	<582..732	CDD:481241	38/174 (22%)
		CD1_tandem_CHD5-9_like	979..1095	CDD:349315	59/276 (21%)
		CD2_tandem	1112..1162	CDD:349306	24/55 (44%)
		PLN03142	1197..>1803	CDD:215601	388/622 (62%)
		SANT	2073..2133	CDD:197842	24/101 (24%)
		BRK	2672..2716	CDD:197800	15/101 (15%)