DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kis and chd7

DIOPT Version :9

Sequence 1:	NP_001137761.1	Gene:	kis / 33185	FlyBaseID:	FBgn0266557	Length:	5517	Species:	Drosophila melanogaster
Sequence 2:	XP_002936158.2	Gene:	chd7 / 100379668	XenbaseID:	XB-GENE-877230	Length:	2969	Species:	Xenopus tropicalis

Alignment Length:	4567	Identity:	1252/4567 - (27%)
Similarity:	1717/4567 - (37%)	Gaps:	1800/4567 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 PRMPA-SPQQQQQQHQQWGAAHGAQHLAALQQQQAQQQQQQVQQQQQAPPQQQQQAAMLQAQQQH 590
            |..|. |..||....|.:|......|                   .....|.|.:........|:
Frog    30 PENPVNSMAQQMPMDQGFGTLQSPLH-------------------HSTSNQNQSKLTHFDHYNQY 75

  Fly   591 HQQQLSMYGQPMGQQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQLQHSINDIVGGG 655
            ..|::.|..||......|....:..|              ..|.|....  .|:.|       ||
Frog    76 EPQKMHMIDQPNRMMANTPGNGIASP--------------HSQYHNTPV--PQVPH-------GG 117

  Fly   656 NSSGATGGAQNQHQQQPQL---AAMSSPLHQQNLPNMHHLIQPTMETTQPTQQQQQTSQQQQQPQ 717
            ...|...|.||. :..|..   .:|..|...| :|:.   |:|      |.|||.|  |||..|.
Frog   118 GQMGVYPGMQND-RHGPSFVDNGSMWGPRAVQ-VPDQ---IRP------PYQQQSQ--QQQPAPS 169

  Fly   718 QPQATLTSPHHQQMQH---QSPIHQQQQSPHHQQHLPSYNQSQQ---QFDPFANILGDNQPAASQ 776
            .||......|.|||.:   :.....||..|...|.:..::|.|:   |.:||....|
Frog   170 GPQGPPHPQHVQQMGNYMVRGDFSMQQHGPLQSQRMNQFSQGQEGLNQGNPFLGASG-------- 226

  Fly   777 QTMSPAHVSSPVPAQMQQQQHQTQQQPSQQVPQSQQQQVSQPQQQTQQQ---QPSTPSHHLSSIL 838
                |.|:|           |..||.|:          :....:.|.||   .|.|..|..|...
Frog   227 ----PGHLS-----------HVPQQNPN----------MGSSLRHTVQQFHHHPPTTLHGESVAH 266

  Fly   839 NETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNS 903
            :...:.|.|...||.....|.:|.|.:..|     || :::|...|....|:.||.  |::||
Frog   267 SPRFSPNPSQQGAVRPQSLNFNSRNQTVPS-----PT-LNNSGQYSRYPYSNLNQG--LVNNT-- 321

  Fly   904 HGGNSESAQNAGVDVGLFDNNSMSSNSAAVAAVA--SNAASAAAALLDSNSQSSNAEFEKNQSEG 966
                           |:..|..:::|:....:|.  .||..                |..|.|:|
Frog   322 ---------------GMNQNLGLTNNTPMTPSVPRYPNAVG----------------FPSNSSQG 355

  Fly   967 EGLGVVEGVIANETDLPQDENSVSKTQDITLSTELPTIQDDLQEKPTAEMEQTQLGQSLGDLSKS 1031
                                          |..:.|.       .|:..:.|.
Frog   356 ------------------------------LMHQQPI-------HPSGSLNQM------------ 371

  Fly  1032 LLEEPKTVEESGEDKSQSAPGVAPPADPIIPV-----TQPPQQQMPPIGMPM---------HP-- 1080
               .|:|:..|....:.::|   ||..|:..:     |.|||.:....|:||         ||
Frog   372 ---NPQTMHPSQPQGTYASP---PPMSPLKAMSNPAGTPPPQVRPGSAGIPMDVGSYPNMPHPPP 430

  Fly  1081 --------------IAPGYEAQAQG-----------QGHMPPMMPPYGGAPGMYPPYPMLHQQEI 1120
                          |.|....|:|.           .|||.|     .|.||:....|...|:.:
Frog   431 THQPPGSMGMGQRNIGPRNIQQSQAFMGMSSAPREMGGHMRP-----NGCPGVSHADPQAIQERM 490

  Fly  1121 AALQQ-------QIQELYCM----------PPGHELQHQDKLMRMQERLNL-----LTQHEVNDQ 1163
            .:.||       |.|...|.          ||.|. .||......|...|.     :.||..::.
Frog   491 MSGQQHPGHQSFQQQMANCQPHPAMHHQSSPPSHS-HHQPWTSLHQSPQNTPQKVPVHQHSPSES 554

  Fly  1164 CAGGPQCLLFQNVPPM--YGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQV 1226
                   .|..:||.|  ...|...|:|.:.. .|.:.|.|          |:|.|.||...
Frog   555 -------FLDNSVPDMTRISGPNASLMNTEDF-LPSMQSQT----------PQKKRKKKNNH--- 598

  Fly  1227 GQQQDLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSA 1291
                                          ::.|....|.|          .||....:.|:
Frog   599 ------------------------------IATDKTVGGFG----------LEGFPGENSDL--- 620

  Fly  1292 NELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKAKK-PKDPNDPNSTETPAAVKKRAGASKRR 1355
             .:|.:.||. |||||:..:.||:|      :.||||| ||:|..|...:.|...|::
Frog   621 -LIDGAPDGK-KKKKPKVKKEPKEP------KEPKAKKEPKEPKAPKQPKPPKEPKEK------- 670

  Fly  1356 KQYGEDGAEQTGEGSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNED 1420
                                            :.:||
Frog   671 --------------------------------KVKTT---------------------------- 675

  Fly  1421 EKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRR 1485
                                   ||..:..|:::                 |:......|.||:.
Frog   676 -----------------------TPKPKASKKTS-----------------NKSDAEGSAQKKKV 700

  Fly  1486 NRGRIVPESDGEDDTLDRTPPPS---PPPDSEMDS--NKRRSSRNTQRKKYIDDVMLRFSDDENS 1545
            |  ::.||. .|...||:|||||   |||:.|.||  .||||||..:||:|.:|:..:.||:|..
Frog   701 N--KVKPEG-VEPLDLDKTPPPSSPPPPPEEEDDSGVQKRRSSRQVKRKRYTEDLEFKISDEEPD 762

  Fly  1546 LLVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTS 1610
                           :|...::.|:..::|.|.|.
Frog   763 ---------------DADGRDSPSNTSQSELQDGL------------------------------ 782

  Fly  1611 AVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQD 1675
                                          |.:..||:.:::.|:.|::|
Frog   783 ------------------------------DAEGPVVEKIMSCRLTKKQL--------------- 802

  Fly  1676 EEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKD 1740

Frog   803 ----------------------------------------------------------------- 802

  Fly  1741 KDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKA 1805

Frog   803 ----------------------------------------------------------------- 802

  Fly  1806 NDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMEN 1870
                                                        :.|||
Frog   803 --------------------------------------------ESGEE---------------- 807

  Fly  1871 KPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPF 1935
                  :::||::|||:|:|||||.|.|.|||.| |:|:..||:||:.||.|. .....|||:.|
Frog   808 ------VEIEEFYVKYKNYSYLHCHWATLEELEK-DKRIQQKIKRFKAKQGQN-KFLSEIEDDLF 864

  Fly  1936 NQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQR 2000
            |.|:.||||:||::..||| :||...||||||.||||||.||||::|:|..|||:   |.|:..|
Frog   865 NPDYVEVDRILDVATSTDE-NGEPVCHYLVKWCSLPYEDSTWELKQDLDQAKIEE---FEKLQSR 925

  Fly  2001 S-EWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQS 2064
            . |.:..:||..:.|||.|.:..||..||||.|||||:|||.|:|||..||||||||||||||||
Frog   926 EPETERVERPPADDWKKSESSREYKNNNSLREYQLEGVNWLLFNWYNKRNCILADEMGLGKTIQS 990

  Fly  2065 LTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESG 2129
            :||::.:|..||.|||||||||||||||:|||..||::||||||||..|::.||.||.|:|...|
Frog   991 ITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRKTIQLYEMYFKDPQG 1055

  Fly  2130 KVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLS 2194
            |::|...||:.:|||||||:||..:|:..:||..|||||||||||||||||||:.::|||:|||:
Frog  1056 KIIKGAYKFHAIITTFEMILTDCPELRNIHWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLT 1120

  Fly  2195 GTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSL 2259
            ||||||.:.|||||||||||.:|.|:..||.|||.|:|||:|.|||.:||||||||||:||||:|
Frog  1121 GTPLQNTVEELFSLLNFLEPDRFPSESNFMQEFGDLKTEEQVQKLQGILKPMMLRRLKEDVEKNL 1185

  Fly  2260 APKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTS--ANIPNLMNTMMELRKCCIHPYLLNGA 2322
            |||||||||||||||||||||.|||:||:||.||...  ||:|||:||||||||||.||||:|||
Frog  1186 APKEETIIEVELTNIQKKYYRAILEKNFAFLSKGGGGGHANVPNLLNTMMELRKCCNHPYLINGA 1250

  Fly  2323 EEQIQYDFKSQHGEDPESY-YKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYL 2386
            ||:|..:|:..|..||..: .:.:..:|||:||||||||||||.|||||||||||||||||||||
Frog  1251 EEKILEEFRETHNCDPSDFQLQAMTQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYL 1315

  Fly  2387 VYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQ 2451
            :.|:||:||||||:||||||.||||:|||.||||||||||:|||||||||||||.||:|||||||
Frog  1316 IQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQ 1380

  Fly  2452 NDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLS 2516
            ||||||||||||||.|.||||||:.||:||||||||||:||||||||||||:.:.:.....:|||
Frog  1381 NDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDNATNGVQQLS 1445

  Fly  2517 KKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRS 2580
            ||||||||:||||||:||:::.|.||||||||.||.|||..||:||| |||||:||||.|||||:
Frog  1446 KKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILSRRTHTITIESEGKGSTFAKASFVASGNRT 1510

  Fly  2581 DITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG---HEDVMELNSEESSNE 2642
            ||::|||:||.|||||.::|.|......|  ||:..||.|.|.:.:.   .:::||.:..||.:|
Frog  1511 DISLDDPNFWQKWAKKAELDLDVLNGRNT--LVIDTPRVRKQTRLFSAVKEDELMEFSDLESDSE 1573

  Fly  2643 NSDEEGGIGLRSRRRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLL 2707
            :..     .::.||.::|                      :||        :|:||||:|||.||
Frog  1574 DKP-----SIKPRRPQDK----------------------SLG--------YARSECFRVEKNLL 1603

  Fly  2708 SFGWGRWSELLELGQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKI 2772
            .:|||||:::|..|:|||...:.|||...|.||:|||..|:|||.||.||||||||||||:.:.:
Frog  1604 VYGWGRWTDILSHGRFKRQLSEQDVETICRTILVYCLNHYRGDENIKGFIWDLITPTEDGQTRAL 1668

  Fly  2773 SRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINAS 2837
            . :||||...|||||.|.|                  ..|.|:.|..|.:
Frog  1669 V-NHSGLSAPVPRGRKGKK------------------VKSQNSQPVLKHA--------------- 1699

  Fly  2838 AVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIK 2902
                         .|.:....|. .:.|.:|||||..|.||||||||||||::.|||||...:|.
Frog  1700 -------------DWLQSCNPDT-LFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIGDQADKIL 1750

  Fly  2903 DNTPISELPI-RPPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGA 2966
            :....||:.: .|.|...:||:.||:.. .|||||:|.:|||.|.|..:||||.|||:...|
Frog  1751 EGADSSEVDVWIPEPFHAEVPTDWWDNE-ADKSLLIGVFKHGYEKYNSIRADPALCFLERAG--- 1811

  Fly  2967 AGDDLAVTSLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSS 3031
            ..|..|:.:                  :..||....|       |||
Frog  1812 MPDAKAIAA------------------EQRGTDMLAD-------GGD------------------ 1833

  Fly  3032 SENASGGNDKTESENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKND 3096
                 ||:...|.|       :..||...||.| .|:|             |.||
Frog  1834 -----GGDFDREDE-------DPEYKPARLPFK-DDID-------------EFAN---------- 1862

  Fly  3097 AQVSASVSCDPADSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDS 3161
                           ||                      .|.|:.|.|
Frog  1863 ---------------SP----------------------LEDKEEEME----------------- 1873

  Fly  3162 AAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDE 3226
                                                    |:.|:...:....|
Frog  1874 ----------------------------------------PTGKSGEGSTELGH----------- 1887

  Fly  3227 EESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPP 3291
                               ..||:...|.|||||:||||||:||:::::
Frog  1888 -------------------LYWPNTSSLTTRLRRLITAYQRSYKRQQMR---------------- 1917

  Fly  3292 LSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGS 3356
                     |..||::
Frog  1918 ---------QDAQMKI------------------------------------------------- 1924

  Fly  3357 CSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKME 3421
                                                                   ::..|:.:.|
Frog  1925 -------------------------------------------------------DRRRRRPREE 1934

  Fly  3422 LAAKERESQRLQLIPK--KWNRREEYEFLRVLTGYGVDLHVSTPMASSNGSSLSPDWTKFKQMAH 3484
            :.|.|.|.:.: :..|  ||.||||.:|.||::.:||..         :.:....||.:|:..|.
Frog  1935 VRALEAEREAI-ITEKRQKWTRREEADFYRVVSTFGVIF---------DNAKQKFDWNQFRAYAR 1989

  Fly  3485 LERKSDETLTDYYKVFVAMCKR--QAGLKLSESERGLEGIIEEIEKEHAKLILDRLEVLAKLRE- 3546
            |::||||:|..|:..|||||:|  ..|.|..|....|..:||.|.:|.|...|.|:|:|.|:||
Frog  1990 LDKKSDESLEKYFSCFVAMCRRVCHMGTKPDEDICDLSMLIEPITEERASRTLYRIELLRKIREQ 2054

  Fly  3547 VARNPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFI 3611
            |..:|.|.||||||..:.|.|:||:.|:||::|:....|||:.|::..|.|||..||.|:.:.|
Frog  2055 VLNHPQLNERLKLCQPSIDLPEWWDCGKHDRDLLVGAAKHGVSRTDYHILNDPELSFLEAHRSF- 2118

  Fly  3612 RELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNE 3676
                                                      |..|.:|
Frog  2119 ------------------------------------------AQNKGSS---------------- 2125

  Fly  3677 SVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTN 3741

Frog  2126 ----------------------------------------------------------------- 2125

  Fly  3742 LNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKCSDAEDKKFSEEKPSSPAVPD 3806
               ..|:...|:|      |...                             :|:..|..|
Frog  2126 ---QPSNLPILIP------PGPG-----------------------------YSDTPPIMP---- 2148

  Fly  3807 GKVSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSI 3871
                      :.||.:|..||:.|:..::.||.|:::..|.|.|.:.:.||:..::...||...:
Frog  2149 ----------STPNPDEKGSGNEEAITEKVEDPVIKEEAEVKEEQAEDTAEKSIKQESDLEAIPV 2203

  Fly  3872 ESEPSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEV-MKEKEKAVEEECKKQAAELKA 3935
            :.|.....||.:.|:....|.|..|.:.||......:....|| :..::|..:||.....:..:.
Frog  2204 KDEIKMTEETPVGPKSISEKGSEEDDEKLDYDDKSEESSQAEVGIASQDKNFDEESNASLSTARD 2268

  Fly  3936 RFPDLEVIQPATVKQQKLEKPKLEMCMIR------WFKDFALERRIAHIVACVESGNWPVDSK-- 3992
            ...|...::..       |:..|.|...|      |.||..:..|:.:|...|..|.|||:.:
Frog  2269 ETRDGFYLEDG-------EQSGLHMLRERTFSFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQM 2326

  Fly  3993 YSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVA-SSASAA 4056
            :.......|.|..::.        |.|::||                   .:.:..|| .|.|.:
Frog  2327 FDFPGLLPGYTPTAVD--------SPLQKRS-------------------FAELSMVAQGSYSGS 2364

  Fly  4057 STSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSA 4121
            ...|..|||:|.                                 |:||
Frog  2365 EDISASPQVSQE---------------------------------TALS---------------- 2380

  Fly  4122 GGVSGLSVPSAGSGVGKKRKRHIAIDVETERA-------KLHALLNSSTMAPKDWESEIANMEAL 4179
                 ||||.      ::|:|...::||.|||       ::.|.|..|.|..::.:.::.::
Frog  2381 -----LSVPR------QRRRRRRKVEVEAERAAKRRNLMEMVAQLRGSQMGAENGQEKVVDL--- 2431

  Fly  4180 SGSSGRGRGGNSSASSGMQPPPAHQHASLSRQ-SSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPK 4243
               |...|...||.||         ..||:.| .....|.|...|.||....:.|.:..:.:...
Frog  2432 ---SNASREATSSTSS---------FPSLTSQFLLNNSSTPVSDAFKTQMERLQAGLSCTPTRHL 2484

  Fly  4244 MNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLD--DTLNKLMKKNNC 4306
            :|                ..:.|...|.|:            ..|.:..::  |.|....|:.:.
Frog  2485 LN----------------GSLIDGEPPMKR------------RRGRRKNVEGLDLLFMSNKRTSL 2521

  Fly  4307 TIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSN 4371
            :::|..:     .|..||.:         :|.|..::||  ..|:.|...:...||:..:.....
Frog  2522 SVDENDV-----TKAYDEDI---------ETPPTRNIPS--PGQLEPETRIPVINLEDGTRLVGE 2570

  Fly  4372 QKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNAL-LA 4435
            :.|                                                  .:||.:..| |.
Frog  2571 EAP--------------------------------------------------KNKDLVEWLKLH 2585

  Fly  4436 QTMATDPQTFLKQQQKMM--QFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDM 4498
            .|...|..:::.:...|:  .|..|.|:                  :....:|:.:.:|
Frog  2586 PTYTVDMPSYVPKTADMLFSHFQKPKQK------------------RHRCRNPNKLDIN------ 2626

  Fly  4499 TSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMP 4563

Frog  2627 ----------------------------------------------------------------- 2626

  Fly  4564 GPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPR-- 4626
               .|||:|.|||:||:.||::||..||.::.|.:||.|||.:.|.|.|.:.::.....|...
Frog  2627 ---TLTGDERVPVVNKRNGKKMGGAMAPPMRDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFD 2688

  Fly  4627 -----PASMESGYGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTA 4686
                 |...|.|     ....|.||.|.::           .:||.:.....||.   |.....:
Frog  2689 RLLTGPVVREEG-----ASRRGRRPKSEIA-----------KAAAAAAVASTSGI---NPLLMNS 2734

  Fly  4687 ASAALDQAALQFGSLAGLNPSLLANL----PGLGAF-----DPKNPLAAFDPKNPLLSMSFGGMP 4742
            ..|.:|.|:||  :|..|....||.|    |||.|.     |.|||.|..    ||:      :|
Frog  2735 LFAGMDLASLQ--NLQNLQSLQLAGLMGFPPGLAAAAAAGGDSKNPAAML----PLM------LP 2787

  Fly  4743 GMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQA 4807
            ||..:|        |:|    |:|||.|      ..|||                  ..|..:.|
Frog  2788 GMAGLP--------NMF----GLGGLLN------NPLAA------------------GSSNSTTA 2816

  Fly  4808 QSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPFL 4872
            .||......:|.|.:||.:.::....:|.....:| :.|.|.:..:.|    .|.:.||.. |||
Frog  2817 SSQGETEDGTSKADEKKTETEEDAKDSEKTDNVSA-TDSVGAATTTAG----LSTNPLAFS-PFL 2875

  Fly  4873 FPN--PSLLYP----PMGLGGLN-PYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSH 4930
            ...  |.|.||    |.|||||. |.....:||.||.               |:|...:.....:
Frog  2876 LSTMAPGLFYPSMFLPPGLGGLTLPGFPSLAGLQSAV---------------SSSEEKAADDCEN 2925

  Fly  4931 QSQSKSSQSRNTTASAN 4947
            |..|.:.:|.:.||.::
Frog  2926 QEPSDAEESMDKTADSS 2942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	BASP1	1554..1786	CDD:283191	11/231 (5%)
		HepA	1676..2527	CDD:223627	445/854 (52%)
		SDA1	<1693..>1854	CDD:283052	1/160 (1%)
		CHROMO	<1879..1919	CDD:237991	23/39 (59%)
		Chromo	1941..1996	CDD:278797	33/54 (61%)
		DEXDc	2048..2197	CDD:238005	99/148 (67%)
		Helicase_C	2350..2464	CDD:278689	100/113 (88%)
		RR_TM4-6	3728..>3877	CDD:283990	24/148 (16%)
		BRK	4569..4613	CDD:197800	22/43 (51%)
chd7	XP_002936158.2	Med15	15..>469	CDD:312941	125/622 (20%)
		Med15	351..>598	CDD:312941	65/325 (20%)
		CD1_tandem_CHD5-9_like	783..848	CDD:349315	32/276 (12%)
		CD2_tandem_CHD5-9_like	866..923	CDD:349310	35/60 (58%)
		PLN03142	955..>1482	CDD:215601	383/526 (73%)
		BRK	2550..2591	CDD:369408	9/90 (10%)
		BRK	2629..2673	CDD:197800	22/43 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	564	1.000	Domainoid score	I232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1491	1.000	Inparanoid score	I105
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001075
OrthoInspector	1	1.000	-	-		otm47615
Panther	1	1.100	-	-	O	PTHR45623
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3575
SonicParanoid	1	1.000	-	-		X648
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.090