Protein Alignment kis and rad54b

DIOPT Version :10

• Sequence 1: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Sequence 2: NP_001121509.1
• Gene: rad54b / 100158622
• XenbaseID: XB-GENE-5839240
• Length: 897
• Species: Xenopus tropicalis
• Alignment Length: 849
• Identity: 220/849 - (25%)
• Similarity: 368/849 - (43%)
• Gaps: 173/849 - (20%)

  Fly  1784 LTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKER 1848
            |:.:.||:|. .:...:|:....|.::..|..:.:|:|.......||..           |....
 Frog    10 LSGNPAKKPR-FIPPGKVNAACPDTETKHSITDSTDKKQLSSRAFEERC-----------GLNTV 62

  Fly  1849 VKEGEESVKKENDEKTE-------------ADMENKPEPVFIDVEEYFVKYRNFSYLHCE-WRTE 1899
            :...|.|.:..:..||.             |..|:|.|   ::....|.||  ||.:.|: .:.:
 Frog    63 LPRAEGSAQPLSSNKTAIMTSVPVCRSVAGAIKEHKNE---VEESSSFAKY--FSVVWCKASKKK 122

  Fly  1900 EELLKGDRRVAAKIRRFQQKQSQQLNIFE----NIED-EPFNQDFT------EVDRVLDMSVHTD 1953
            .:..:||..:.||.|....|..:..:|.:    .|:| |...:..|      |:: |:.:....|
 Frog   123 HKKWEGDAVLIAKGRAVTLKDMEGKDIGKGTGYKIKDLESLEEGHTLMIGGKEIE-VMSIMSPED 186

  Fly  1954 ETSGETTKHYLVKWKSLPYEDC-----TWELEEDVDNDKIEQYLR------------------FN 1995
            ..||......:....|.|.|..     |..|..|......|...:                  ..
 Frog   187 YNSGRCFHSVVTSPASTPSESIQMKPFTNPLRNDRKGASKENMFKELQNIKPRHDPCAPNAFVMP 251

  Fly  1996 KIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNC---------- 2050
            |..|..:|...|...|.:...::.   |...: |||:|.||:.:|       :.|
 Frog   252 KPTQHHQWAYNKTGLPIVDVVVDP---YLAVH-LRPHQKEGILFL-------YECVMGMRVNERF 305

  Fly  2051 --ILADEMGLGKTIQSLTFVHSVYEYGIRGPF---------LVIAPLSTIPNWQREFEGWTDMNV 2104
              |||||||||||:|.::.:.::..   :||:         |::.|.|.:.||::||:.|..
 Frog   306 GAILADEMGLGKTLQCISLIWTLIR---QGPYGGKPVIKKALIVTPGSLVKNWRKEFQKWLG--- 364

  Fly  2105 VVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAH 2169
                   |.:..:...:..:|.|  :.:|.|: ::|||.::||::.....:::.::.:.:.||.|
 Frog   365 -------TERIRVFAVDQDHKVE--EFMKSPL-YSVLIISYEMLLRCLEQIQSLDFDVVICDEGH 419

  Fly  2170 RLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGS--LRT 2232
            ||||.:.|....|..|....|::|||||:||::.|.|:|:.|:.|:...|...:...|..  :|:
 Frog   420 RLKNTSIKTTSALASLTCSKRIILSGTPVQNDLQEFFALIEFVNPAALGSLSTYRKIFEEPIIRS 484

  Fly  2233 -------------EEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILE 2284
                         ||...:|..|....:|||.::.:.|.|.||.|:|:....:..|...||.:|.
 Frog   485 REPTATTEEKNLGEERAAELARLTGLFILRRTQEVINKFLPPKIESIVFCRPSQFQLDLYRKLLN 549

  Fly  2285 Q---NFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHGE--DPESYYKN 2344
            .   ....|..|.:|   |:|: .:..|:|.|.||:||          |::..|:  :|:....|
 Frog   550 SRTVKSCLLGSGESS---PHLV-CIGALKKLCNHPFLL----------FRTIQGKSTNPDQDEHN 600

  Fly  2345 LILS------------------AGKMVLIDKLLPKLK--ANGHRVLIFSQMVRCLDILEDYLVYR 2389
            |..|                  :||::::..||.:::  :...||::.|...:.|:||:|.....
 Frog   601 LYESVAEVFPQDYDGAKISESESGKLLVLSNLLSRIRELSPSERVVLVSNYTQTLNILQDLCNQH 665

  Fly  2390 KYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDL 2454
            .|...|:||:.....||..:|.::...|..|:|||.:||||:|:||..|..:|:||.||||.||:
 Frog   666 GYSCTRLDGQTPVTQRQHIVDGFNSKYSTDFIFLLSSKAGGVGLNLIGASHLILYDLDWNPANDI 730

  Fly  2455 QAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKE 2519
            ||.||..|.|||..|.|||||...:.|.:::.:...|.||..||:..     :|...:.:.|..|
 Frog   731 QAMARVWRDGQRHTVHIYRLLTTGSLEEKIYQRQISKQGLSGAVVDL-----TKKSEHIRFSLDE 790

  Fly  2520 IEDL 2523
            :.:|
 Frog   791 LRNL 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kis	NP_001137761.1	Atrophin-1	221..>533	CDD:460830
		Med15	<1056..>1265	CDD:312941
		PRK12678	1319..>1500	CDD:237171
		PTZ00121	<1419..1923	CDD:173412	32/152 (21%)
		CD1_tandem_CHD5-9_like	1851..1918	CDD:349315	19/80 (24%)
		CD2_tandem_CHD5-9_like	1937..1995	CDD:349310	13/86 (15%)
		PLN03142	2029..>2606	CDD:215601	165/556 (30%)
		PTZ00341	<3662..3887	CDD:173534
		BRK	4568..4611	CDD:462196
rad54b	NP_001121509.1	HepA	<277..776	CDD:440319	161/536 (30%)
		DEXHc_RAD54B	281..515	CDD:350824	71/256 (28%)