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Protein Alignment Tbc1d15-17 and GYP6

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_012491.3	Gene:	GYP6 / 853406	SGDID:	S000003580	Length:	458	Species:	Saccharomyces cerevisiae

Alignment Length:	490	Identity:	98/490 - (20%)
Similarity:	161/490 - (32%)	Gaps:	167/490 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 MRD--QHLIENAETS----RSG---GEVY----------------AILTTENQK--LKKTFAELD 227
            |:|  |..|::.||.    :.|   ||:|                .:|..||..  |...|..||
Yeast     1 MKDVLQWAIDHYETRDQLVQKGIWKGELYHDSIFKENSRGWLWKALLLCDENNNCLLTDNFKGLD 65

  Fly   228 IGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGS 292
            :.|.....:|                                 :|..||......|..:
Yeast    66 LNQFGLVPVP---------------------------------MLADGDNYDENHNANV------ 91

  Fly   293 TNSACSSNGQSRGGSAEKSPADS-ELETLNAQDEKIVNNLPDRQRVERG---HPLTETQWLEFQT 353
            ......||..|..|....:|.:: |...|:..::|...:|      .:|   .|||..:.||...
Yeast    92 PKRVLHSNVSSSVGIRRLTPVEAVEKHPLSDDNDKTKGSL------SKGSDEKPLTLRETLEIID 150

  Fly   354 PD-GRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWL 417
            .| .||     :.:.||:...|.:   ::.:.|.||.|     :.:.|..:.|.
Yeast   151 LDLSRI-----MLDDIFQEPKVHA---QMRQLLYNYLL-----IHQSEHLQYKQ----------- 191

  Fly   418 AMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGM 482
                       |:.|....|         .||.:.|.|..| |.||.:|:.:
Yeast   192 -----------GFHEILSVI---------YLQLYHGTDLDN-TDLQNVLIIF------------- 222

  Fly   483 SDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHD 547
            :.|:..|..|..||.:    .:.:.:.|||.  |.:..:...|:::     |...|.....:..:
Yeast   223 NKLMNQIEPIFYNEEN----LINWDKRVFTK--IFRICLPDLFSKV-----FYQPPKTGSGKKKN 276

  Fly   548 SD-----NMYFCFRWLLVWYKRELNSEDVLKLWECLWT-------RLPCPNFHLLFSVAILDQET 600
            .|     |:.:..||..:.:.|||..:.||.:|:.:.|       .:.|....||.|  |.|:..
Yeast   277 VDHLIHSNLIWLIRWTRLLFLRELPLKYVLIVWDHVLTFNYPLDIFIACTIITLLLS--IYDELH 339

  Fly   601 RVIIDSQY-------EFTEILKHVNELSGNIDVQK 628
            .::....|       ||.|::.|..::....|..|
Yeast   340 ELVSQGDYEHTNNNDEFVELILHFKKIFEKEDASK 374

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.