DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tbc1d15-17 and AT5G53570

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001154777.1	Gene:	AT5G53570 / 835439	AraportID:	AT5G53570	Length:	577	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	139/561 - (24%)
Similarity:	214/561 - (38%)	Gaps:	171/561 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 ILGNIPDYVQPPFQRSPKSRPGVLISGDRQTS---PDNYQIIGLSGSTNSACSSNGQSRGGSAEK 310
            |.|..|.......:||..|..    ||:..:|   |.:......|.|::|..|||..|...|...
plant    19 ITGKFPANQMKALRRSYTSTS----SGNSSSSSSLPSSSSSSLPSSSSSSPPSSNSNSYSNSNSS 79

  Fly   311 SPADSELETLNAQDEKIVNNL--------PDRQRV------ERGHPLTETQWLEFQTPDGRISDS 361
            |.:.|   .::.:....|.||        .||:|.      :|...||..||....||:|::.|.
plant    80 SSSSS---WIHLRSVLFVANLSSPSSVTSSDRRRKSPWSRRKRKWALTPHQWRSLFTPEGKLRDG 141

  Fly   362 --ARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVER--IERRKQKSIEYYNMKAQWLAM--- 419
              ..:|::..| ||..|:|.|||.|||..|..:.|..||  ::.:|:|..|....:.|.|..
plant   142 GVGFLKKVRSR-GVDPSIRAEVWLFLLGVYDLNSTSEEREAVKTQKRKEYEKLQRRCQMLLKCGN 205

  Fly   420 --------TTTQEANF-C-----GYRERKCQIEKDV---KRTDRS-------------LQFFA-- 452
                    ..:.|||. |     .|:.......:||   ..||.|             |..||
plant   206 GSTDNLEELPSDEANSQCVRFVDDYKITGPMTSQDVVSALNTDSSDTDSCEDNEDVLLLSSFAHS 270

  Fly   453 -----GEDNPN------------------------------------------------------ 458
                 .|||.|
plant   271 DEKKPEEDNSNNNSEENSSLLVAAASEVQVEVAVHEDFSTWQRIIRLDALRADSEWANYSPYSTA 335

  Fly   459 ----------------------------LTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVN 495
                                        ...|..||..|.||:.::||.|||||||:|||.:...
plant   336 ITESKARRLAESVGLKDYDHLESCRLYHAARLVAILEAYAMYDPEIGYCQGMSDLLSPILAVISE 400

  Fly   496 EVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLV 560
            :.:.||||||||:....||.:|:||::.|.:.:.::|:..::.|:.::.:..:::..|.:|.:||
plant   401 DHEAFWCFVGFMKKARHNFRLDEAGIQRQLSIVSKIIKNKDSQLYKHLENLQAEDCSFVYRMVLV 465

  Fly   561 WYKRELNSEDVLKLWECLWT-------------------RLPCPNFHLLFSVAILDQETRVIIDS 606
            .::|||:.|..|.|||.:|.                   :.|..:..||:::|.|....::||..
plant   466 MFRRELSFEQTLCLWEVMWADQAAIRAGVGKSPWSRIRQQAPPTDDLLLYAIAALVLRRKLIIQK 530

  Fly   607 QYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGS-ETL 646
            .....||::..|.::|.::|.|.|..|..:.:.|... |||
plant   531 YSSMDEIVEECNSMAGQLNVWKLLDDAHHLVVTLHDKIETL 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	89/371 (24%)
AT5G53570	NP_001154777.1	TBC	<370..486	CDD:214540	46/115 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820