DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbc1d15-17 and AT3G59570

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_001325779.1	Gene:	AT3G59570 / 825126	AraportID:	AT3G59570	Length:	744	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	119/504 - (23%)
Similarity:	191/504 - (37%)	Gaps:	138/504 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 TTSECRAFNTRPIEPSGGATTRSRVMRAQL--EDLSSVEVRHR-----------GQTIRFMRKG- 168
            :|||.|              |:.||.|.:.  |.|...::.|.           |..:..|||.
plant   100 STSEYR--------------TQLRVARRERYNELLKQCQMMHSTVGTGSLAYVVGSKVMDMRKSY 150

  Fly   169 ANGVHSEFFFQHGNADLFVRSMRDQH------LIENAETSRSGGEVYAI-LTTENQKLKKTFAEL 226
            .|.|..|...:...|.|......|.|      ..|.:...|||....:: |.:.:..:.:|
plant   151 KNEVVKEDIDESREACLDGHENTDNHGDWSNNDTEKSPVRRSGSSSESVDLVSPDSTIYET---- 211

  Fly   227 DIGQIKASQLPRESWL----PNKLAGILGNIPDY-VQPPFQRSPKSRPGVLISGDRQTS------ 280
                  :|.:|..|..    |...|..:.:.|.. |...|.||...:.| |.:.|.:||
plant   212 ------SSFVPPSSPYGFPSPGPFADDIFDFPSLPVTDLFGRSSLGKKG-LSTPDEETSTQSDLR 269

  Fly   281 --PDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQD-EKIVNNLPDRQRVERGHP 342
              .:......:..:.:.....:|.|.....  :..:||:|.::.|. ||:.:::...:.|
plant   270 SEDERMHSFRIDKNADLVIEPHGSSYNDVT--ASINSEIEVVHLQSVEKLSHSVCTSEIV----- 327

  Fly   343 LTETQWLEFQTPDG-RISD-----SARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIER 401
                        || ||||     |||  |...|||.|:..|...|       ||: .|
plant   328 ------------DGLRISDVPETPSAR--ETHTRGGTVKEDRVSEW-------LWT-LH------ 364

  Fly   402 RKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGIL 466
                                              :|..||.|||..|:|:  ||..||..:..||
plant   365 ----------------------------------RIVVDVVRTDSHLEFY--EDPGNLGRMSDIL 393

  Fly   467 MTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDID-QAGMKTQFAQIRR 530
            ..|...:...||.||||||::|.:.:..:..|.||||...:.....||.:: ..|:..|...:.|
plant   394 AVYAWVDPATGYCQGMSDLVSPFVFLFEDNADAFWCFEMLIRRTRANFQMEGPTGVMDQLQSLWR 458

  Fly   531 LIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLW 579
            :::..:..:|:::....:::::|.||.|||.::|||:....|::||.:|
plant   459 ILQLTDKEMFSHLSRIGAESLHFAFRMLLVLFRRELSFNKALRMWEMMW 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	20/86 (23%)
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	57/212 (27%)
AT3G59570	NP_001325779.1	TBC	<362..512	CDD:214540	49/189 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820