Protein Alignment Tbc1d15-17 and tbc1d17

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_005164004.1
• Gene: tbc1d17 / 554092
• ZFINID: ZDB-GENE-050522-79
• Length: 639
• Species: Danio rerio
• Alignment Length: 669
• Identity: 225/669 - (33%)
• Similarity: 328/669 - (49%)
• Gaps: 122/669 - (18%)

  Fly    41 ILFTHDGVLLKKASAEHIADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQPNDSIMIADDSQ---- 101
            ::|..:||.|...:.....|....|.:.:||.....|        |||.|     :.||.:
Zfish    10 LIFEKEGVYLHTNAKRSNQDTTIPGFIRIVERDGEPA--------LEWSP-----VEDDGRNAPA 61

  Fly   102 -----------------DQG---DWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQ 146
                             |.|   |||::.       |..:.|.....|:..:|..::.|    ..
Zfish    62 VFYTKKDGEGGEEETKFDPGYEPDWAVIS-------TVKQDRRQEQPPVRETGHWSSFS----LP 115

  Fly   147 LEDLSSVEVRHR---GQTIRFM-RKGANGVHSEFFFQHGNADLFVRSMRDQHLIENAETSRSGGE 207
            |.:|.|:. |.|   |:....: .:|.:.:....|.:.|..:| :::|  |..|..| .|...|.
Zfish   116 LSELYSLR-RARFSLGRNFLVLTTRGGDPLPPLHFHRGGTREL-LKAM--QRYIRLA-PSPMDGR 175

  Fly   208 VYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPGVL 272
            ::.....::..|.::|.||.:....::.|                :..::|.|:..:
Zfish   176 LFLAYPHDSGALSQSFDELHLFDDTSADL----------------VSRFIQDPYATT-------- 216

  Fly   273 ISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADS------------ELETLNAQDE 325
                         ..|.|..||....:..........:||.|.            ||.|..|:
Zfish   217 -------------FGGFSKVTNFFRGALRNPESPLNNRSPQDPHFPHSADEEPGFELITCGAE-- 266

  Fly   326 KIVNNLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYL 390
                 |..|..|:||.||  ..|.:|..|:||::|..::|||:||||:|..||.|||||||.:|.
Zfish   267 -----LGPRPEVKRGKPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIVPYLRKEVWKFLLGFYP 324

  Fly   391 WSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEAN---FCGYRERKCQIEKDVKRTDRSLQFFA 452
            |:.|..||.:....|:.||:.||.||.:::..||..   |.|||.   .||:||.||||...||:
Zfish   325 WNSTTKEREDILMVKTDEYFRMKVQWKSVSEEQEMRNSLFRGYRS---LIERDVNRTDRHNSFFS 386

  Fly   453 GEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDID 517
            |.:||.||||..:||||.||||||||||||||||:|:|.:..|||::|||..|||:||..||:..
Zfish   387 GNENPGLTLLHDVLMTYCMYNFDLGYVQGMSDLLSPLLFVTQNEVESFWCLTGFMDLVHQNFEES 451

  Fly   518 QAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRL 582
            |..||.|..|:..|:...:..|.:|:.|.||.::.|||||||:|:|||.:.||:|.|||.|||||
Zfish   452 QEAMKQQLLQLSLLLRALDPELCDYLDSQDSGSLCFCFRWLLIWFKREFSFEDILSLWEVLWTRL 516

  Fly   583 PCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLP 647
            ||.|||||.:.:||:.:...:|.|.::|..||||:|||:..:|:|..|..||.|||||...:.|.
Zfish   517 PCENFHLLMACSILESQKEELIGSNHDFNSILKHINELTMKLDLQSVLCGAEAIYLQLTHCKELS 581

  Fly   648 NDIRSIIGEPLLPAAAGEE 666
            ..::.::| ..:|:.:.|:
Zfish   582 PKVQEVLG-LRIPSGSSEQ 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	35/177 (20%)
		TBC	369..598	CDD:214540	126/231 (55%)
tbc1d17	XP_005164004.1	DUF3548	5..211	CDD:192931	46/245 (19%)
		TBC	303..538	CDD:214540	126/237 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	260	1.000	Domainoid score	I1930
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2348
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	1	1.000	-	-		FOG0002107
OrthoInspector	1	1.000	-	-		otm24835
orthoMCL	1	0.900	-	-		OOG6_101355
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2140
SonicParanoid	1	1.000	-	-		X1395
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.860