Protein Alignment Tbc1d15-17 and TBC1D13

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_060671.3
• Gene: TBC1D13 / 54662
• HGNCID: 25571
• Length: 400
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 83/383 - (21%)
• Similarity: 129/383 - (33%)
• Gaps: 136/383 - (35%)

  Fly   363 RIKELIFRGGVVQ-SLRPEVWKFLLNYYLWSDTHVERIERRKQKSI-----EYYNMKAQWLAMTT 421
            :::||.|.|...: .||...||.||||.        .:||....||     |.|   ||:|....
Human    25 KLRELSFSGIPCEGGLRCLCWKILLNYL--------PLERASWTSILAKQRELY---AQFLREMI 78

  Fly   422 TQ----EANFCGYRER-------------------------KCQIEKDVKRTDRSLQFF-AGEDN 456
            .|    :||....||.                         ..||:|||:|....:.|| ...|.
Human    79 IQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATDY 143

  Fly   457 PNLTLL----------------------------------------------------------- 462
            |.|.:|
Human   144 PCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHW 208

  Fly   463 ---QGILMTYVMYNFDLGYVQGMSDLLAPILEI----------QVNEVDTFWCFVGFMELVFTNF 514
               :.||..|...|..:.|||||::::.|:...          :..|.|||:||...|..:..||
Human   209 EVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNF 273

  Fly   515 ----DIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLW 575
                |..|.|:..:..::...::..:..|:..::..:....:|.||||.:...:|....||:::|
Human   274 IKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIW 338

  Fly   576 ECLWTRLPCPNFHLLFSVAIL----------DQETRVIIDSQYEFT---EILKHVNEL 620
            :.|:......:|.||...|:|          |....:.:...|..|   :||:...||
Human   339 DSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKEL 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
		TBC	369..598	CDD:214540	74/350 (21%)
TBC1D13	NP_060671.3	TBC	32..367	CDD:214540	73/345 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810