Protein Alignment Tbc1d15-17 and tbc1d16

DIOPT Version :10

• Sequence 1: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_012814267.2
• Gene: tbc1d16 / 448159
• XenbaseID: XB-GENE-986691
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 179/715 - (25%)
• Similarity: 289/715 - (40%)
• Gaps: 143/715 - (20%)

  Fly    24 SSVEEDVQNLPQQG------TGNILFTHDGVLLKKASAEHIADLNTSGSLSLVEYSRSIAEMPRR 82
            ||...|...|...|      .|.|:|:.:.|.:.  ..|.:.|:.:.....|..|... .|....
 Frog    11 SSKASDFLTLSSGGGSSSILDGEIIFSKNNVCVH--PPELLQDVGSHHPGYLCVYMEK-DEFLGT 72

  Fly    83 RLLLEWQPNDSIMIADDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQL 147
            .|:|.|.||..|    ..||:.....:...|...|.....|  |.:|  |....||||:......
 Frog    73 TLILAWVPNSRI----QRQDEEALRYITPESSPIRKNPRKR--NRQP--PGSAPTTRSKPAIISK 129

  Fly   148 EDLSS------------------VEVRHRGQTIRFMRKGANGV---------------------- 172
            ||:..                  .|...:|:..|.:...::.|
 Frog   130 EDVGREVNSPTERDPSYGSAEGVEEGTEQGEDERSLDLSSDEVSKDSTLDSDSDAFSSPFCLSPI 194

  Fly   173 -------HSEFFFQHGNADLFVRSMRD--QHLIENAETSRSGGEVYAILTTENQK---LKKTFA- 224
                   .|..|.::.|.|.....|..  ..|..|::.....|:.......|.||   |::|..
 Frog   195 SEALGESSSSVFLENENRDESNSHMSSYASSLNANSQLPEINGQGVPAKWEEQQKLLALEQTCGV 259

  Fly   225 -ELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIG 288
             .:|:||:::.:.                        |........|.|:...|::   .|::..
 Frog   260 FRVDLGQMRSLRF------------------------FFSDEACTSGQLVVASRES---QYKVFH 297

  Fly   289 LSGSTNSACSSNGQSRGGSAEKSPA--------DSELETLNAQDEKIV-------NNLPDRQRVE 338
            .             ..||..:.|..        :::|:.....::|..       .|||..:
 Frog   298 F-------------HHGGLGKLSEVFQQWKYCRETQLKEQQVTEDKTCLHFSIQRPNLPSSE--- 346

  Fly   339 RGHP-------LTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHV 396
             .||       |..|.|||.....|::.:..::::|||.||:..|||.|||.|||.||.|..|..
 Frog   347 -SHPEEGMYRRLDVTSWLEHLNEVGQVEEEYKLRKLIFFGGIDPSLRGEVWPFLLGYYPWEITSE 410

  Fly   397 ERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTL 461
            :|...|..:..||..::.:.::|:.|.:..|  ::..:..::|||.|||||.|||.||||||:..
 Frog   411 DREALRVHRREEYSQIQKKRVSMSPTAQKEF--WKNVQFTVDKDVVRTDRSNQFFRGEDNPNVES 473

  Fly   462 LQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFME-LVFTNFDIDQAGMKTQF 525
            ::.||:.|.:|:..:||.||||||:||||...::|.||||||||.|: .:|.:...|:. |:.|.
 Frog   474 MRRILLNYAVYSPGVGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEY-MEKQL 537

  Fly   526 AQIRRLIEFANAPLFNYMRS--HDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFH 588
            ..:|.|:...:...:.::.|  .|...|.||.||:|:.:|||....:.|::||..|.......||
 Frog   538 LYLRELLRLVHPRFYQHLYSLGEDGLQMLFCHRWILLCFKREFPDSEALRMWEACWAHYQTDYFH 602

  Fly   589 LLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSI 653
            |...|||:......:|:.|....::|.|.:.|:.:::.:..|:.|..:..|.:....:|..:..:
 Frog   603 LFLCVAIIVLYGDDVIEQQLPTDQMLLHFSNLAMHMNGELVLRKARSLLYQFRLLPRIPCSLHDL 667

  Fly   654  653
             Frog   668  667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	93/231 (40%)
tbc1d16	XP_012814267.2	TBC	385..613	CDD:214540	92/230 (40%)