Protein Alignment Tbc1d15-17 and plx

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001163511.1
• Gene: plx / 40704
• FlyBaseID: FBgn0261261
• Length: 1572
• Species: Drosophila melanogaster
• Alignment Length: 668
• Identity: 127/668 - (19%)
• Similarity: 249/668 - (37%)
• Gaps: 154/668 - (23%)

  Fly    96 IADDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQLEDLSSVEVRHRGQ 160
            ::||.|:. .||   :..|..:|.|.....|          .....::||..|   |.:.||
  Fly   652 LSDDEQEI-VWA---KFCGSEKTNSPVAEQN----------QFLMMLLRAHCE---SRQQRH--- 696

  Fly   161 TIRFMRKGANGVH------SEFFFQH-GNADLFVRSMRD-QHLIENAETSRSGGEVYAILTTENQ 217
                       ||      |||..|: |.:.:|:::.|. .:..:|....:...:..|:.:...:
  Fly   697 -----------VHDTAENRSEFLNQYLGGSTIFMKAKRSLTNSFDNLLKRKPSKDDIAVPSHNLR 750

  Fly   218 KLKKTFAE-----------------------------------LDIGQIKASQLPRE------SW 241
            .:::..||                                   :|| .||....|:|      ||
  Fly   751 DIREGSAEPLGTQSPPEGFRSRSNTVGASPSSKPTAEQLKSPMMDI-FIKVGNSPKEAETHQGSW 814

  Fly   242 ---------LPNKLAGILGNIP-DYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSA 296
                     .|:|  |:...:| :::.|  .|.|..|      |.|..:  ..:.:..:....:.
  Fly   815 RQAILNSVVTPSK--GLDSEVPTEFLSP--MRKPAKR------GKRDAA--ELRELWRTAIRQTI 867

  Fly   297 CSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLP-DRQRVERGHPLTETQWLEFQTPDGRISD 360
            ..:..::.....:....::||:.:....|:||   | |:|.:||...:.|..    .|..|...|
  Fly   868 MLNRMETENAMLQARQNENELKRIKLDYEEIV---PCDKQLIERWEQIIERN----STQIGNKKD 925

  Fly   361 SARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLA--MTTTQ 423
            ...:...| |.||.:|.|.:||.||...:..:...|:      .|....:|.....|.  :|..|
  Fly   926 PKVLGHAI-RTGVPRSKRGDVWTFLAEQHSMNTAPVD------TKRFPNFNTPYHMLLKHLTEHQ 983

  Fly   424 EANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAP 488
            .|.|.           |:.||..:.||:..........|..:|..|.:.:.:|||.||:. .:..
  Fly   984 HAIFI-----------DLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLG-FICG 1036

  Fly   489 ILEIQVNEVDTFWCF--VGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNM 551
            :|.:..:|.::|...  :.|...:.|.:..|....:.|..|:.||::.....|:.::..:|....
  Fly  1037 VLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPT 1101

  Fly   552 YFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKH 616
            .:...|:|..:..:.....|.::::.|:  |...:....|::|:|....:.:: ::..|.||:.:
  Fly  1102 LYAAPWILTVFSSQFPLGFVARVFDLLF--LESSDVIFKFAIALLSVHKQQLL-AKDNFEEIMDY 1163

  Fly   617 VNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSIIGEPLLPAAAGEEIDGGMVDEEPTYSDD 681
            :..:...::.....|:.:.::             ...||:.|    |..:::..::.||.|.::.
  Fly  1164 LKTVVPKMEHTCMEQIMKLVF-------------SMDIGKQL----AEYKVEYNVLQEEITTTNH 1211

  Fly   682 GFDELVKELTPEEKVRQQ 699
            ..:.|.:|.|..:.:.||
  Fly  1212 HLEMLNREKTQNQHLEQQ 1229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	23/101 (23%)
		TBC	369..598	CDD:214540	50/232 (22%)
plx	NP_001163511.1	PTB_TBC1D1_like	301..601	CDD:269967
		DUF3350	835..880	CDD:288663	6/54 (11%)
		TBC	933..1152	CDD:214540	51/239 (21%)
		RILP-like	<1176..1267	CDD:304877	13/71 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940